Catalog No.
YHC15701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Asp155
Predicted molecular weight
20.96 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P05230
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Endothelial cell growth factor, HBGF-1, Fibroblast growth factor 1, FGF1, ECGF, Acidic fibroblast growth factor, aFGF, Heparin-binding growth factor 1, FGF-1, FGFA
Engineering overexpressing SYNGR1 inhibited the progression of GBM cells by suppressing the intracellular FGF1-mediated LDs accumulation and cytoskeleton remodeling., PMID:40478501
Reprogramming FGF1 from the natural growth factor to the engineered heparan sulphate biosensor., PMID:40437501
In Silico Analysis of Novel circRNA-miRNA-mRNA Axis in BRAFV600E Melanoma: Implications for Primary to Metastasis Transformation and TIME Modulation., PMID:40436810
Investigating the Mechanisms of Pazopanib-induced Hepatotoxicity: Insights from Network Toxicology, Microarray Analysis, and Machine Learning., PMID:40417760
AgRP neuron hyperactivity drives hyperglycemia in a mouse model of type 2 diabetes., PMID:40371641
Mitochondrial NNT Promotes Diastolic Dysfunction in Cardiometabolic HFpEF., PMID:40340422
Temporal mineralocorticoid receptor activation regulates the molecular clock and transcription of cardiovascular disease modulators in myeloid cells., PMID:40272082
FGF1ΔHBS ameliorates DSS-induced ulcerative colitis by reducing neutrophil recruitment through the MAPK pathway., PMID:40258390
Loss of NgBR causes neuronal damage through decreasing KAT7-mediated RFX1 acetylation and FGF1 expression., PMID:40192836
A key role for parabrachial nucleus CGRP neurons in FGF1-Induced anorexia., PMID:40189100
Colonic epithelial-derived FGF1 drives intestinal stem cell commitment toward goblet cells to suppress inflammatory bowel disease., PMID:40188210
CAUSAL ASSOCIATION BETWEEN SEPSIS AND FIBROBLAST GROWTH FACTORS AS WELL AS THEIR RECEPTORS LEVELS: A TWO-SAMPLE MENDELIAN RANDOMIZATION STUDY., PMID:40138723
Thauvin-Robinet-Faivre Syndrome: A FIBP Variant in an Adolescent with Segmental Overgrowth and Thyroid Carcinoma., PMID:40099975
Potential therapeutic targets for Alzheimer's disease: Fibroblast growth factors and their regulation of ferroptosis, pyroptosis and autophagy., PMID:40096963
Identifcation of the FGF family as therapeutic targets and prognostic biomarkers in the microenvironment of head and neck squamous cell carcinoma., PMID:40086631
KLF5 enhances CXCL12 transcription in adipose-derived stem cells to promote endothelial progenitor cells neovascularization and accelerate diabetic wound healing., PMID:40038579
Novel Approach to Overcome Osimertinib Resistance Using Bromodomain and Extra-Terminal Domain Inhibitors., PMID:40036147
Prefrontal FGF1 Signaling is Required for Accumbal Deep Brain Stimulation Treatment of Addiction., PMID:40013979
aFGF gene-modified adipose-derived mesenchymal stem cells promote healing of full-thickness skin defects in diabetic rats., PMID:40001190
Identification and Co-expression Analysis of Differentially Expressed LncRNAs and mRNAs Regulate Intramuscular Fat Deposition in Yaks at Two Developmental Stages., PMID:39971835
Environmental high temperature induced cartilage damage through triggering programmed necrosis mediated by producing left-handed DNA., PMID:39955869
Influence of Simulated Altitude Exposure (2500 m) on Patients with Fontan Palliation Based on Circulating Hypoxia-Associated Factors., PMID:39940657
Effects of FGF-related gene polymorphisms on cerebral infarction in patients treated with direct oral anticoagulants., PMID:39924006
FGF1 alleviates polystyrene nanoplastics-induced neuroinflammation through the suppression of lipophagy., PMID:39892539
Genes related to neural tube defects and glioblastoma., PMID:39885289
β-eudesmol inhibits cell growth and enhances cell chemosensitivity of NPC through targeting FGF1/FGFR signaling., PMID:39864398
Single-cell transcriptome analysis revealing mechanotransduction via the Hippo/YAP pathway in promoting fibroblast-to-myofibroblast transition and idiopathic pulmonary fibrosis development., PMID:39855369
Exploration and verification of the therapeutic mechanism of shenfu injection in sepsis-induced myocardial injury., PMID:39823512
Recombinant Porcine FGF1 Promotes Muscle Stem Cell Proliferation and Mitochondrial Function for Cultured Meat Production., PMID:39772551
Hepatocyte-Derived FGF1 Alleviates Isoniazid and Rifampicin-Induced Liver Injury by Regulating HNF4α-Mediated Bile Acids Synthesis., PMID:39731358
Transcriptomic integration and ligand-receptor crosstalk reveal the underlying molecular mechanisms between hip cartilage and subchondral bone in osteonecrosis of femoral head., PMID:39708930
May dental implant macro and microgeometry modifications influence peri-implant bone repair in smokers? A randomized clinical trial., PMID:39633324
Characterization of Serratia marcescens (OK482790)' prodigiosin along with in vitro and in silico validation for its medicinal bioactivities., PMID:39587466
Spatial transcriptomics reveals molecular cues underlying the site specificity of the adult mouse oral mucosa and its stem cell niches., PMID:39547226
Clinical efficacy and mechanism of the combination of autologous platelet-rich gel and recombinant human acidic fibroblast growth factor in the management of refractory diabetic foot., PMID:39539934
FNDC4 alleviates cardiac ischemia/reperfusion injury through facilitating HIF1α-dependent cardiomyocyte survival and angiogenesis in male mice., PMID:39516487
The role of lipase maturation factor 1 in hypertriglyceridaemia and atherosclerosis: An update., PMID:39483624
Low-energy extracorporeal shockwave therapy improves locomotor functions, tissue regeneration, and modulating the inflammation induced FGF1 and FGF2 signaling to protect damaged tissue in spinal cord injury of rat model: an experimental animal study., PMID:39453843
Stromal reprogramming overcomes resistance to RAS-MAPK inhibition to improve pancreas cancer responses to cytotoxic and immune therapy., PMID:39441902
Early intervention using long-term rhythmic pulsed magnetic stimulation alleviates cognitive decline in a 5xFAD mouse model of Alzheimer's disease., PMID:39419435
Exploring common pathogenic association between Epstein Barr virus infection and long-COVID by integrating RNA-Seq and molecular dynamics simulations., PMID:39391317
Comprehensive in silico analysis of prognostic and immune infiltrates for FGFs in human ovarian cancer., PMID:39385288
Fibroblast growth factor 1 (FGF1) improves glucose homeostasis, modulates gut microbial composition, and reduces inflammatory responses in rainbow trout (Oncorhynchus mykiss) fed a high-fat diet., PMID:39383919
Differential chromatin accessibility and Gene Expression Associated with Backfat Deposition in pigs., PMID:39349998
Sodium Alginate/Poly (Acrylicacid) Hydrogel Composite, Potential Carrier for Fibroblast Growth Factor1 (FGF1) Delivery., PMID:39340197
Flavonoid chrysin activates both TrkB and FGFR1 receptors while upregulates their endogenous ligands such as brain derived neurotrophic factor to promote human neurogenesis., PMID:39331585
Overcoming drug resistance of cancer cells by targeting the FGF1/FGFR1 axis with honokiol or FGF ligand trap., PMID:39329123
Placenta-derived SOD3 deletion impairs maternal behavior via alterations in FGF/FGFR-prolactin signaling axis., PMID:39325622
Paracrine FGF1 signaling directs pituitary architecture and size., PMID:39320918
Exploring angiogenic pathways in breast cancer: Clinicopathologic correlations and prognostic implications based on gene expression profiles from a large-scale genomic dataset., PMID:39302921