Catalog No.
YHC13901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly21-Pro402
Predicted molecular weight
45.27 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P05121
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PLANH1, Endothelial plasminogen activator inhibitor, SERPINE1, Plasminogen activator inhibitor 1, PAI1, PAI, PAI-1, Serpin E1
Elevated cerebrospinal fluid levels of SERPIN E1 in participants with lewy body diseases., PMID:40514404
NFATC2/SERPINE1/JAK3/STAT3 signaling feedback loop in gastric cancer: immune evasion and anti-PD-1 resistance., PMID:40512406
A network toxicology approach to decipher paraben-induced molecular dysregulation in breast cancer pathogenesis., PMID:40512387
Prothrombotic fibrin clot phenotype as a risk factor for persistent left ventricular thrombus following acute myocardial infarction., PMID:40505869
PAI1 regulating CHRNA1 contributes to primary focal hyperhidrosis: Clinical and experimental studies., PMID:40503176
Thermodynamics and selection of the plasminogen activator inhibitor-1 latency transition., PMID:40501902
Plasminogen supplementation improves lysis of inflammatory retained traumatic hemothorax., PMID:40497789
Simvastatin inhibits proliferation and migration, promotes oxidative stress and ferroptosis in colon cancer., PMID:40487942
Single-cell transcriptome sequencing reveals new epithelial-stromal associated mesenchymal-like subsets in recurrent gliomas., PMID:40483536
The Human Myometrial Transcriptome and the DNA Methylome of Testosterone-treated Patients Resemble the Myometria from Fibroid Patients., PMID:40474053
Identification of a Novel Mutation in the SERPINE1 Gene Causing Clinical Hyperfibrinolysis in English Springer Spaniel Dogs., PMID:40470612
New horizons in the pharmacological management of venous thromboembolism., PMID:40469483
Therapeutic efficacy of budesonide suspension combined with poractant alfa injection for neonatal respiratory distress syndrome and its effect on serum ferritin and PAI-1 expressions., PMID:40469168
Regulatory effects of lncRNA PVT1 on transcriptome in human breast cancer MDA-MB-231 cell line determined by in silico analyses., PMID:40464801
Association between adiposity distribution and high-sensitivity C-reactive protein, adipokines, interleukins and plasminogen activator inhibitor-1., PMID:40461792
[Effects of total extract of Anthriscus sylvestris on immune inflammation and thrombosis in rats with pulmonary arterial hypertension based on TGF-β1/Smad3 signaling pathway]., PMID:40461203
Restoration of NOX4 signalling reverses endothelial colony-forming cell angiogenic dysfunction associated with experimental and clinical diabetes., PMID:40457435
Vascular Assessment in Adult Survivors of Childhood Cancer: A St. Jude Lifetime Cohort Study Report., PMID:40446733
BRD4 regulates PAI-1 expression in tumor-associated macrophages to drive chemoresistance in colorectal cancer., PMID:40437184
Leptin and PAI-1 Levels Are Decreased After a Dietary Intervention in Patients with Irritable Bowel Syndrome., PMID:40429752
Inflammation-induced TET3/mir-3942 axis impedes the proliferation and invasion ability of trophoblast cells through destabilization of SERPINE1 in preeclampsia., PMID:40424676
Association between PAI-1 gene - 657 4G/5G polymorphism and preeclampsia in Egyptian women: a case-control study., PMID:40420039
Blood-Brain Barrier Integrity and Transport of Major Hormones are Unchanged in Mice With Euglycemic Hyperinsulinemia., PMID:40418654
Overview: PAI-1 inhibitors and clinical applications., PMID:40403845
Peripheral Blood Plasminogen Activator Inhibitor 1 and Tissue-Type Plasminogen Activator-Inhibitor Complex Levels for the Diagnosis and Prediction Value of Venous Thromboembolism in Malignant Tumors., PMID:40401695
Sustained Expression of Plasminogen Activator Inhibitor-1 in Patients Recovered From COVID-19 Disease., PMID:40398396
LNCAROD was stabilized through N6-methyladenosine methylation and exerted its anticancer effects in lung squamous cell carcinoma by inhibiting SIRT1 activity via CCAR2., PMID:40386722
Combined effects and potential mechanisms of volatile organic compounds on thyroid disease in the US population: An integrated epidemiological and computational toxicology study., PMID:40378728
Quercetin Reduces Vascular Senescence and Inflammation in Symptomatic Male but Not Female Coronary Artery Disease Patients., PMID:40375481
Dogs with sepsis are more hypercoagulable and have higher fibrinolysis inhibitor activities than dogs with non-septic systemic inflammation., PMID:40370829
Phosphatase-independent activity of smooth-muscle calcineurin orchestrates a gene expression program leading to hypertension., PMID:40367288
Hemostatic parameters in transgender women receiving gender-affirming hormone therapy: A shift to a cisgender female pattern?, PMID:40367073
Differential associations between kidney and vascular health biomarkers in young adults stratified by blood pressure status: The African Prospective study on the Early Detection and Identification of Cardiovascular disease and Hypertension study., PMID:40366098
Tumor microenvironment modulation by SERPINE1 increases radioimmunotherapy in murine model of gastric cancer., PMID:40355586
Targeting neutrophil extracellular traps: SERPINE1 and THBS1 as non-invasive biomarkers for early detection of liver fibrosis in metabolic dysfunction-associated Steatotic liver disease., PMID:40349409
GEO combined with quantitative protein trait loci identify causative proteins in hypertrophic cardiomyopathy., PMID:40348582
Environmental Aromatic Amine Induces Pulmonary Arterial Hypertension Associated With Estrogen Signaling and Serpine1., PMID:40344275
Assessment of Blood Endothelial Cell Biomarkers in Women and Men with Abnormal Body Mass and Paroxysmal Atrial Fibrillation Based on CHA2DS2-VASC Score: A Retrospective Study., PMID:40332159
How Does a Porcine Herpesvirus, PCMV/PRV, Induce a Xenozoonosis., PMID:40332048
Causal associations between epigenetic age and thromboembolism: a bi-directional two-sample Mendelian randomization study., PMID:40325450
Plasminogen Activator Inhibitor 1 Controls Abdominal Aortic Aneurism Formation via the Modulation of TGF-β/Smad2/3 Signaling in Mice., PMID:40323694
Quercetin ameliorates ox-LDL-induced cellular senescence of aortic endothelial cells and macrophages by p16/p21, p53/SERPINE1, and AMPK/mTOR pathways., PMID:40319296
Decoding per- and polyfluoroalkyl substances (PFAS) in hepatocellular carcinoma: a multi-omics and computational toxicology approach., PMID:40317014
Identification of PANoptosis related biomarkers to predict hepatic ischemia‒reperfusion injury after liver transplantation., PMID:40316717
Effect of Plasminogen Activator Inhibitor-1 on extracellular matrix homeostasis in scaffold-free spheroids from human chondrocytes., PMID:40316399
In situ protein corona-camouflaged supramolecular assemblies remodel thrombotic microenvironment for improved arterial homeostasis., PMID:40315315
CircMYO9A inhibits influenza A virus replication by dampening haemagglutinin cleavage via increasing SERPINE1/PAI-1 expression., PMID:40314425
SARS-COV-2 causes significant abnormalities in the fibrinolysis system of patients: correlation between viral mutations, variants and thrombosis., PMID:40302923
Liver steatosis is positively associated with plasminogen activator inhibitor-1 in apparently healthy individuals with overweight and obesity: A FibroScan-Based Cross-Sectional study., PMID:40301952
Plasminogen activator inhibitor 1 is a novel predictor in human serum/follicular fluid for diminished ovarian reserve., PMID:40301911
For research use only. Not for human or drug use.
