Catalog No.
YHC13001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu134-Glu384
Predicted molecular weight
30.43 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P05106
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
GPIIIa, Integrin beta-3, CD61, ITGB3, Platelet membrane glycoprotein IIIa, GP3A
Carbon-Encapsulated Iron Nanoparticles Seeking Integrins in Murine Glioma., PMID:40321805
The Reactive Oxygen Species Scavenger N-Acetyl-L-Cysteine Reduces Storage-Dependent Decline in Integrin α IIb β 3-Mediated Platelet Function, Inhibiting Pre-Activation of Integrin and Its β 3 Subunit Cleavage., PMID:40321407
Integrin β3-mediated platelet extracellular vesicle adhesion facilitates vascular smooth muscle cell dysfunction in postinjury intimal hyperplasia., PMID:40303298
Glanzmann thrombasthenia: a multi-center study of demographics, clinical spectrum, and treatment efficacy., PMID:40301132
Novel homozygous frameshift mutation of ITGB3 in the Glanzmann thrombasthenia patient with abnormal bone metabolism and congenital bone defects., PMID:40251671
Qilong capsule regulates microglial function and inhibits platelet activation after multiple cerebral infarctions by regulating the P2Y12/AC/cAMP signalling pathway., PMID:40054638
c-Rel drives pancreatic cancer metastasis through Fibronectin-Integrin signaling-induced isolation stress resistance and EMT activation., PMID:39975057
Clinicopathological analysis of anti-VEGF drug-associated renal thrombotic microangiopathy: A case series and review of the literature., PMID:39879682
Nootkatone Derivative Nootkatone-(E)-2-iodobenzoyl hydrazone Promotes Megakaryocytic Differentiation in Erythroleukemia by Targeting JAK2 and Enhancing JAK2/STAT3 and PKCδ/MAPK Crosstalk., PMID:39791711
Modeling the Impact of Extracellular Vesicle Cargoes in the Diagnosis of Coronary Artery Disease., PMID:39767589
Dengue infection changes the expressions of CD154 and CD148 in human platelets., PMID:39710119
Platelets as key cells in endometriosis patients: Insights from small extracellular vesicles in peritoneal fluid and endometriotic lesions analysis., PMID:39698929
Targeted delivery of rapamycin and inhibition of platelet adhesion with multifunctional peptide nanoparticles for atherosclerosis treatment., PMID:39490419
Compound K Promotes Megakaryocytic Differentiation by NLRP3 Inflammasome Activation., PMID:39456190
A loss of tuning of both pro-coagulant and inflammatory responses in monocytes in patients with preeclampsia., PMID:39332076
Size and fluorescence calibrated imaging flow cytometry: From arbitrary to standard units., PMID:39238272
Evaluation of circulating microvesicles and their procoagulant activity in patients with COVID-19., PMID:39175048
[Pedigree Analysis and Molecular Mechanism Study of Hereditary Glanzmann Thrombasthenia Caused by Compound Heterozygous Mutation of the ITGA2B Gene]., PMID:38951065
Xuefu Zhuyu decoction alleviates deep vein thrombosis through inhibiting the activation of platelets and neutrophils via sirtuin 1/nuclear factor kappa-B pathway., PMID:38908490
Platelet mass cytometry reveals dysregulation of prothrombotic pathways in essential thrombocythemia., PMID:38845541
The Role of TLR-2 in Lethal COVID-19 Disease Involving Medullary and Resident Lung Megakaryocyte Up-Regulation in the Microthrombosis Mechanism., PMID:38786077
Role of CD61+ low-density neutrophils in promoting hepatocellular carcinoma metastasis through CCDC25 upregulation., PMID:38761780
Transient synaptic CD61 pairing with CD103 increases the cytotoxicity of antigen-specific T cells., PMID:38671324
Role of NuMA1 in breast cancer stem cells with implications for combination therapy of PIM1 and autophagy inhibition in triple negative breast cancer., PMID:38645153
Platelet-derived TGF-β1 induces functional reprogramming of myeloid-derived suppressor cells in immune thrombocytopenia., PMID:38574321
Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity., PMID:38561495
Platelet Microparticle-Derived MiR-320b Inhibits Hypertension with Atherosclerosis Development by Targeting ETFA., PMID:38556340
Myeloid sarcoma with RBM15::MRTFA (MKL1) mimicking vascular neoplasm., PMID:38374236
Platelet Proteome Reveals Novel Targets for Hypercoagulation in Pseudoexfoliation Syndrome., PMID:38338682
Lipoprotein apheresis affects the concentration of extracellular vesicles in patients with elevated lipoprotein (a)., PMID:38307884
Platelet derived exosomes disrupt endothelial cell monolayer integrity and enhance vascular inflammation in dengue patients., PMID:38235130
Exploring thrombus composition in cerebral venous thrombosis: the first case report with initial insights and implications for treatment advancements., PMID:38221542
Platelet Analysis in the Thrombus Plus Serum BNP for Detecting Clot-Related Atrial Fibrillation. Results From the ITACAT Multicentric Registry., PMID:38091189
Differential Expression of the hTERT Gene in Umbilical Cord-Derived Mesenchymal Stem Cells Cocultured with B Cell Precursor Leukemia Cell Microparticles or CD41+/CD61+ Platelet Microparticles., PMID:38019337
[Comparative study of the effects of intramedullary nail fixation and minimally invasive percutaneous plate internal fixation technique on platelet activation and serum transforming growth factor-β1(TGF-β) 1 and bone morphogenetic protein-2 (BMP-2) in patients with tibial and fibular fracture]., PMID:38012883
Monoclonal antibody-navigated carbon-encapsulated iron nanoparticles used for MRI-based tracking integrin receptors in murine melanoma., PMID:38007065
CD61 identifies a superior population of aged murine HSCs and is required to preserve quiescence and self-renewal., PMID:37939263
Extracellular vesicles in plasma and cerebrospinal fluid in patients with COVID-19 and neurological symptoms., PMID:37795549
OMIP-097: High-parameter phenotyping of human platelets by spectral flow cytometry., PMID:37786346
Comprehensive cell surface protein profiling of human mesenchymal stromal cells from peritoneal dialysis effluent and comparison with those from human bone marrow and adipose tissue., PMID:37603218
Platelet-derived extracellular vesicles promote endothelial dysfunction in sepsis by enhancing neutrophil extracellular traps., PMID:37559007
Plasma extracellular vesicle test sample to standardize flow cytometry measurements., PMID:37538497
Platelet activation and endothelial dysfunction biomarkers in acute coronary syndrome: the impact of PCSK9 inhibition., PMID:37468450
Blockage of Osteopontin-Integrin β3 Signaling in Infrapatellar Fat Pad Attenuates Osteoarthritis in Mice., PMID:37218542
The phenotype of cryopreserved platelets influences the formation of platelet-leukocyte aggregates in an in vitro model., PMID:37143347
Hemostatic In Vitro Properties of Novel Plasma Supernatants Produced from Late-storage Low-titer Type O Whole Blood., PMID:37027803
Modulation of low-dose ozone and LPS exposed acute mouse lung inflammation by IF1 mediated ATP hydrolysis inhibitor, BTB06584., PMID:36993977
Rapid isolation of mature murine primary megakaryocytes by size exclusion via filtration., PMID:36992536
OxLDL sensitizes platelets for increased formation of extracellular vesicles capable of finetuning macrophage gene expression., PMID:36963245
Ormeloxifene, a nonsteroidal antifertility drug promotes megakaryocyte differentiation in leukemia cell line K562., PMID:36950830
For research use only. Not for human or drug use.
