Catalog No.
YHC12801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro59-Ala150
Predicted molecular weight
12.70 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P05091
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ALDH-E2, Aldehyde dehydrogenase, mitochondrial, ALDM, ALDH2, ALDH class 2, ALDHI
L-Theanine Mitigates Chronic Alcoholic Intestinal Injury by Regulating Intestinal Alcohol and Linoleic-Arachidonic Acid Metabolism in Rats., PMID:40507212
The Pathological Role and Therapeutic potential of ALDH2 in acrolein detoxification Following Spinal Cord Injury in Mice., PMID:40501858
Emerging mechanisms underlying formaldehyde toxicity and response., PMID:40480196
Multi-omics unveils BCAA metabolism markers L-leucine and HMGCS1 as prognostic marker for immunotherapy efficacy in non-small cell lung cancer., PMID:40457349
Inhibition of mitochondrial protein import and proteostasis by a pro-apoptotic lipid., PMID:40445107
Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures., PMID:40436827
Liver Receptor Homolog-1 Deficiency Impairs Alcohol-Associated Liver Disease Owing to Decrease of Aldehyde Dehydrogenase 1 Family Member B1 Gene Expression., PMID:40415444
GSNOR plays roles in growth, pathogenicity, and stress resistance by modulating mitochondrial protein COX6B S-nitrosylation in Colletotrichum gloeosporioides., PMID:40407326
Mitochondrial aldehyde dehydrogenase restores the migratory capacity inhibited by high glucose-induced hyperosmolality., PMID:40404697
Diethyldithiocarbamate-Cu4O3 nanocomplex induced mitochondrial and telomerase dysfunction in non-small cell lung cancer., PMID:40377424
Comprehensive analysis of chronic hepatitis B concurrent with non-alcoholic fatty liver disease: a proteomics report based on clinical liver samples., PMID:40361009
From aldehyde metabolism to delay aging: targeting ALDH2 as a novel strategy., PMID:40349798
Impact of the aldehyde dehydrogenase 2 (ALDH2) gene testing on alcohol drinking behaviors among the Chinese Han population: study protocol of a single-center, open-label, randomized, controlled clinical trial., PMID:40336132
TBC1D15 protects alcohol-induced liver injury in female mice through PLIN5-mediated mitochondrial and lipid droplet contacting., PMID:40334909
Proteome-Wide Genetic Study in East Asians and Europeans Identified Multiple Therapeutic Targets for Ischemic Stroke., PMID:40304040
Sex- and ALDH2-dependent differences in alcohol metabolism and psychomotor performance: a study in Han Chinese adults after binge drinking., PMID:40289679
Identification of mitophagy-related genes in patients with acute myocardial infarction., PMID:40287718
Targeting metabolic vulnerability by combining NAMPT inhibitors and disulfiram for treatment of recurrent ovarian cancer., PMID:40280967
Loss of ALDH2 accelerates the progression of pulmonary arterial hypertension through the 4-HNE/ERK1/2-p16INK4a signaling pathway., PMID:40274079
ALDH2 delays ventricular pressure overload-induced heart failure by promoting cardiomyocyte proliferation in mice., PMID:40273968
Acetaldehyde-driven mRNA methylation and expression changes in ethanol-metabolizing enzyme genes., PMID:40252050
Identification and Validation of Ferritinophagy-Related Biomarkers in Periodontitis., PMID:40233623
Hydrogen peroxide-induced oxidative stress alters protein expression in two rat salivary acinar cell lines., PMID:40233540
Conversion of glutamate into proline by the leucine analog BCH enhances biphasic insulin secretion in pancreatic β-cells., PMID:40154614
Transcriptomics-based identification of biomarkers associated with mast cell activation during ischemia-reperfusion injury in kidney transplantation., PMID:40147738
History of mental comorbidities and their relationships with drinking milestones, hazardous drug use, suicide attempts, and the ADH1B and ALDH2 genotypes in 4116 Japanese men with alcohol dependence: An exploratory study., PMID:40146027
Identification of ALDH2 as a novel target for the treatment of acute kidney injury in kidney transplantation based on WGCNA and machine learning algorithms and exploration of its potential mechanism of action using animal experiments., PMID:40103812
Comparative analysis of translatomics and transcriptomics in the longissimus dorsi muscle of Luchuan and Duroc pigs., PMID:40100799
ALDH2 Deficiency and Alcohol Intake in the United States: Opportunity for Precision Cancer Prevention., PMID:40063522
The carcinogenic metabolite acetaldehyde impairs cGAS activity to negatively regulate antiviral and antitumor immunity., PMID:40056967
Acetaldehyde dehydrogenase 2 attenuates lipopolysaccharide -induced endothelial barrier damage by inhibiting mitochondrial fission in sepsis-associated encephalopathy., PMID:40054720
[Research progress of aldehyde dehydrogenase type 2 in head and neck malignant tumors]., PMID:40049649
Understanding the link between ALDH2 genotypes and diabetes., PMID:40046877
CE-MS Metabolomic and LC-MS Proteomic Analyses of Breast Cancer Exosomes Reveal Alterations in Purine and Carnitine Metabolism., PMID:40036676
The combined effect between environmental exposure and oxidative stress-related susceptible gene polymorphisms on human semen quality., PMID:40032748
Exploring Potential Drug Targets in Multiple Cardiovascular Diseases: A Study Based on Proteome-Wide Mendelian Randomization and Colocalization Analysis., PMID:40026415
Mechanisms and preventive measures of ALDH2 in ischemia‑reperfusion injury: Ferroptosis as a novel target (Review)., PMID:40017132
Alda-1 mediates cell senescence and counteracts bone loss in weightlessness through regulating mitophagy., PMID:39983821
ALDH2 Overexpression Improves the Blood-brain Barrier and Represses Mitochondrial Dysfunction in Chronic Cerebral Hypoperfusion Through the SIRT1/ROS Axis., PMID:39964551
Nitroglycerin-responsive gene switch for the on-demand production of therapeutic proteins., PMID:39953326
Integrative Multi-omics Analysis and Mendelian Randomization Reveal Potential Therapeutic Targets and their Stratification in Lung Squamous Cell Carcinoma., PMID:39936431
Hepatic and extra-hepatic metabolism of propylene glycol ethers in the context of central nervous system toxicity., PMID:39929342
Relationship Between Aldehyde Dehydrogenase 2 Gene Polymorphism and Vasodilative Effect of Nitroglycerin on Coronary Arteries., PMID:39928694
Aldh2 and the tumor suppressor Trp53 play important roles in alcohol-induced squamous field cancerization., PMID:39909947
Alda‑1 restores ALDH2‑mediated alcohol metabolism to inhibit the NF‑κB/VEGFC axis in head and neck cancer., PMID:39886980
Characterization of human alcohol dehydrogenase 4 and aldehyde dehydrogenase 2 as enzymes involved in the formation of 5-carboxylpirfenidone, a major metabolite of pirfenidone., PMID:39884816
Urolithin A attenuates apoptosis and ferroptosis in hyperlipidemic tenocytes through PPARδ/ALDH2-mediated antioxidative signaling., PMID:39865940
Oxidative and Excitatory Neurotoxic Stresses in CRISPR/Cas9-Induced Kynurenine Aminotransferase Knockout Mice: A Novel Model for Despair-Based Depression and Post-Traumatic Stress Disorder., PMID:39862084
Potential Mechanisms and Effects of Dai Bai Jie Ethanol Extract in Preventing Acute Alcoholic Liver Injury., PMID:39852118
(E)-2-Octenal inhibits Neofusicoccum parvum growth by disrupting mitochondrial energy metabolism and is a potential preservative for postharvest mango., PMID:39849732
For research use only. Not for human or drug use.
