Catalog No.
YHC11801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala10-Ala163
Predicted molecular weight
19.92 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P05014
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
IFN-alpha-4, Interferon alpha-M1, Interferon alpha-76, Interferon alpha-4B, IFNA4, Interferon alpha-4
SESN1 negatively regulates STING1 to maintain innate immune homeostasis., PMID:39945079
Structural analysis of Spi-B DNA-binding Ets domain recognizing 5'-AGAA-3' and 5'-GGAA-3' sequences., PMID:39892964
CSNK1A1/CK1α suppresses autoimmunity by restraining the CGAS-STING1 signaling., PMID:37723657
Demystifying the impact of prenatal tobacco exposure on the placental immune microenvironment: Avoiding the tragedy of mending the fold after death., PMID:37700485
A Transcriptome Array-Based Approach Links Proteinuria and Distinct Molecular Signatures to Intrarenal Expression of Type I Interferon IFNA5 in Lupus Nephritis., PMID:37445814
Machine learning identifies ferroptosis-related genes as potential diagnostic biomarkers for osteoarthritis., PMID:37378023
Identification of key immune genes of osteoporosis based on bioinformatics and machine learning., PMID:37361541
UXT attenuates the CGAS-STING1 signaling by targeting STING1 for autophagic degradation., PMID:35543189
Identification and validation of the prognostic value of cyclic GMP-AMP synthase-stimulator of interferon (cGAS-STING) related genes in gastric cancer., PMID:33843442
Nuclear cGAS Functions Non-canonically to Enhance Antiviral Immunity via Recruiting Methyltransferase Prmt5., PMID:33296647
The mechanism of action of Spi-B in the transcriptional activation of the interferon-α4 gene., PMID:32111355
Altered molecular signatures during kidney development after intrauterine growth restriction of different origins., PMID:32008055
PA-X antagonises MAVS-dependent accumulation of early type I interferon messenger RNAs during influenza A virus infection., PMID:31076606
Expression Pattern of Individual IFNA Subtypes in Chronic HIV Infection., PMID:29252127
Rb selectively inhibits innate IFN-β production by enhancing deacetylation of IFN-β promoter through HDAC1 and HDAC8., PMID:27267461
BANK1 Regulates IgG Production in a Lupus Model by Controlling TLR7-Dependent STAT1 Activation., PMID:27228057
Formula diet alters small intestine morphology, microbial abundance and reduces VE-cadherin and IL-10 expression in neonatal porcine model., PMID:27005303
Therapeutic Antiviral Effect of the Nucleic Acid Polymer REP 2055 against Persistent Duck Hepatitis B Virus Infection., PMID:26560490
Exome sequencing identifies novel compound heterozygous IFNA4 and IFNA10 mutations as a cause of impaired function in Crohn's disease patients., PMID:26000985
Toll-like receptor 7-mediated type I interferon signaling prevents cholestasis- and hepatotoxin-induced liver fibrosis., PMID:24375615
Posttranscriptional control of type I interferon genes by KSRP in the innate immune response against viral infection., PMID:21690298
Promoter organization of the interferon-A genes differentially affects virus-induced expression and responsiveness to TBK1 and IKKepsilon., PMID:16380379
Repression by homeoprotein pitx1 of virus-induced interferon a promoters is mediated by physical interaction and trans repression of IRF3 and IRF7., PMID:12242290
Preferential binding sites for interferon regulatory factors 3 and 7 involved in interferon-A gene transcription., PMID:11884139
The virus-induced factor VIF differentially recognizes the virus-responsive modules of the mouse IFNA4 gene promoter., PMID:11846978
HHV-8 encoded vIRF-1 represses the interferon antiviral response by blocking IRF-3 recruitment of the CBP/p300 coactivators., PMID:11314014
Selective DNA binding and association with the CREB binding protein coactivator contribute to differential activation of alpha/beta interferon genes by interferon regulatory factors 3 and 7., PMID:10938111
Primary activation of interferon A and interferon B gene transcription by interferon regulatory factor 3., PMID:9707562
Regulation of type I interferon gene expression by interferon regulatory factor-3., PMID:9446577
Silencer activity in the interferon-A gene promoters., PMID:9278440
Synergism between multiple virus-induced factor-binding elements involved in the differential expression of interferon A genes., PMID:9268360
Identification of a member of the interferon regulatory factor family that binds to the interferon-stimulated response element and activates expression of interferon-induced genes., PMID:8524823
Virus-mediated induction of interferon A gene requires cooperation between multiple binding factors in the interferon alpha promoter region., PMID:8226947
Priming does not change promoter sequence requirements for IFN induction or correlate with the expression of IFN regulatory factor-1., PMID:7687628
Detection of human interferon-alpha-encoding gene expression., PMID:8388843
For research use only. Not for human or drug use.
