Catalog No.
YHC11001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala24-Ser179
Predicted molecular weight
19.48 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P04843
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
RPN1, RPN-I, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit, Ribophorin I, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1, Ribophorin-1
Structural insights into the ubiquitin-independent midnolin-proteasome pathway., PMID:40339123
Ubiquitin-proteasome Pathway-linked Gene Signatures as Prognostic Indicators in Prostate Cancer., PMID:40295064
Causal roles of lipids and mediating proteins in diabetic retinopathy: insights from metabolomic and proteomic Mendelian randomization., PMID:40287778
NUB1 traps unfolded FAT10 for ubiquitin-independent degradation by the 26S proteasome., PMID:40217121
Neuronal CDK5RAP3 deficiency leads to encephalo-dysplasia via upregulation of N-glycosylases and glycogen deposition., PMID:40188151
A multi-omics target study for glioblastoma multiforme (GBM) based on Mendelian randomization analysis., PMID:40124114
Dysregulation of N-glycosylation by Rpn1 knockout in spermatocytes induces male infertility via endoplasmic reticulum stress in mice., PMID:40083683
Structural basis for the midnolin-proteasome pathway and its role in suppressing myeloma., PMID:40027645
Global Identification of Anti-Melanoma Cellular Targets by Photochemically Induced Coupling of L-Shikonin Reactions on the Surface of Magnetic Particles., PMID:39771522
Disulfidptosis and Its Hub Gene Slc3a2 Involved in Ulcerative Colitis Pathogenesis, Disease Progression, and Patient Responses to Biologic Therapies., PMID:39769269
Loss of RPN1 promotes antitumor immunity via PD-L1 checkpoint blockade in triple-negative breast cancer - experimental studies., PMID:39705151
The SLE-associated TREX1-P212fs mutation disrupts ER association leading to type I interferonopathy., PMID:39621297
Integrated analysis of disulfidptosis-related genes SLC7A11, SLC3A2, RPN1 and NCKAP1 across cancers., PMID:39612126
Transmembrane E3 ligase RNF128 regulates N-glycosylation by promoting ribophorin I ubiquitination and degradation., PMID:39567208
Matrix stiffness regulates the protein profile of extracellular vesicles of pancreatic cancer cell lines., PMID:39279557
Nub1 traps unfolded FAT10 for ubiquitin-independent degradation by the 26S proteasome., PMID:38915702
Pan-cancer analysis of the disulfidptosis-related gene RPN1 and its potential biological function and prognostic significance in gliomas., PMID:38845861
Proteasome regulation of petite-negativity in fission yeast., PMID:38798546
VCP/p97 UFMylation stabilizes BECN1 and facilitates the initiation of autophagy., PMID:38762759
Transient interdomain interactions in free USP14 shape its conformational ensemble., PMID:38588275
Insight into telomere regulation: road to discovery and intervention in plasma drug-protein targets., PMID:38431573
Proteasome condensate formation is driven by multivalent interactions with shuttle factors and ubiquitin chains., PMID:38408252
Cell surface expression of Ribophorin I, an endoplasmic reticulum protein, over different cell types., PMID:38373565
Intracellular Protein Adsorption Behavior and Biological Effects of Polystyrene Nanoplastics in THP-1 Cells., PMID:38294362
Disulfidptosis-related Protein RPN1 may be a Novel Anti-osteoporosis Target of Kaempferol., PMID:38213143
Bik promotes proteasomal degradation to control low-grade inflammation., PMID:38113109
Downregulation of SLC3A2 mediates immune evasion and accelerates metastasis in oral squamous cell carcinoma., PMID:37927242
MiR-375 promotes cisplatin sensitivity of lung adenocarcinoma., PMID:37625279
Molecular mechanism for activation of the 26S proteasome by ZFAND5., PMID:37595557
Identification of potential drug targets for varicose veins: a Mendelian randomization analysis., PMID:37404740
Molecular mechanisms for activation of the 26S proteasome., PMID:37214989
FAT10 and NUB1L cooperate to activate the 26S proteasome., PMID:37188463
High glucose leads to redistribution of the proteasomal system., PMID:36757058
Gene expression profiles in parathyroid adenoma and normal parathyroid tissue., PMID:35953114
Dominant-Negative Form of SIGIRR: SIGIRRΔE8 Promotes Tumor Growth Through Regulation of Metabolic Pathways., PMID:35900274
Upregulation of ribosome complexes at the blood-brain barrier in Alzheimer's disease patients., PMID:35766008
Comprehensive bioinformatics analysis reveals the hub genes and pathways associated with multiple myeloma., PMID:35192775
Knockdown of Oligosaccharyltransferase Subunit Ribophorin 1 Induces Endoplasmic-Reticulum-Stress-Dependent Cell Apoptosis in Breast Cancer., PMID:34778038
An Ebola, Neisseria and Trypanosoma human protein interaction census reveals a conserved human protein cluster targeted by various human pathogens., PMID:34745452
Comparison of myeloid neoplasms with nonclassic 3q26.2/MECOM versus classic inv(3)/t(3;3) rearrangements reveals diverse clinicopathologic features, genetic profiles, and molecular mechanisms of MECOM activation., PMID:34668265
A novel recognition site for polyubiquitin and ubiquitin-like signals in an unexpected region of proteasomal subunit Rpn1., PMID:34364874
Impaired 26S Proteasome Assembly Precedes Neuronal Loss in Mutant UBQLN2 Rats., PMID:33919255
Polyubiquitin and ubiquitin-like signals share common recognition sites on proteasomal subunit Rpn1., PMID:33617881
Germline ALK variations are associated with a poor prognosis in glioma and IDH-wildtype glioblastoma., PMID:33486679
Dysregulated healing responses in diabetic wounds occur in the early stages postinjury., PMID:33350981
Proteomic Profiles of Thyroid Gland and Gene Expression of the Hypothalamic-Pituitary-Thyroid Axis Are Modulated by Exposure to AgNPs during Prepubertal Rat Stages., PMID:32972137
Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane., PMID:32788342
A Non-structural 1 Protein G53D Substitution Attenuates a Clinically Tested Live Dengue Vaccine., PMID:32402284
The SH3 domain in the fucosyltransferase FUT8 controls FUT8 activity and localization and is essential for core fucosylation., PMID:32350116
A Genome-wide ER-phagy Screen Highlights Key Roles of Mitochondrial Metabolism and ER-Resident UFMylation., PMID:32160526
For research use only. Not for human or drug use.
