Catalog No.
AMC33701
Biological activity
Measured by its ability to enhance LPS-induced IL-6 secretion by mouse splenocytes. The ED50 for this effect is 0.4-2.4 µg/mL.
Expression system
Mammalian Cells
Species
Mus musculus (Mouse)
Protein length
Ala18-Pro345
Nature
Recombinant
Endotoxin level
<0.1 EU/μg of the protein by the LAL method.
Purity
>90% as determined by SDS-PAGE.
Accession
Q4FJP7
Applications
Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, Drug Target
Proteomic profiling reveals immunomodulatory role of IL-33 in ocular bacterial and fungal infections., PMID:40512033
Divergent Immune Pathways in Coronary Artery Disease and Aortic Stenosis: The Role of Chronic Inflammation and Senescence., PMID:40508061
A dendritic cell population responsible for transglutaminase 2-mediated gluten antigen presentation in celiac disease., PMID:40502135
Human Cytomegalovirus UL78 is a Nuclear-Localized GPCR Necessary for Efficient Reactivation from Latent Infection in CD34 + Hematopoietic Progenitor Cells., PMID:40501644
RBPJ/PAF1 Signaling Axis Promotes Cloning Expansion in Paroxysmal Nocturnal Hemoglobinuria Through NOTCH Signaling., PMID:40501337
5-HT7R Deficiency Alleviates ADP-Heptose-Induced Cognitive Impairment via Inhibiting Ferroptosis and Neuroinflammation in Mice., PMID:40501108
Endothelial CLEC5A drives barrier dysfunction and vascular leakage responsible for lung injury in bacterial pneumonia and sepsis., PMID:40498836
VPAC1 and VPAC2 Receptor Heterozygosity Confers Distinct Biological Properties to BV2 Microglial Cells., PMID:40497945
TNF receptor-associated factors: promising targets of natural products for the treatment of osteoporosis., PMID:40496246
Inflammatory and vascular biomarkers as predictors of all-cause death and cardiovascular outcomes in an Australian community-based cohort., PMID:40495286
Naproxen and prednisolone reduced intestinal alteration and permeability and bacterial translocation in rat adjuvant-induced arthritis., PMID:40493287
N6-methyladenosine modification of HCMV IE1 transcript promotes the repressive state of viral genome to achieve latent infection., PMID:40493198
Causal association between immune cytokines and psoriasis: A two-way Mendelian randomization study., PMID:40489870
A novel LRR domain-containing C-type lectin gene with immune regulatory functions protects Penaeus vannamei against Vibrio parahaemolyticus infection., PMID:40484067
Inflammation, antiretroviral therapy continuation, and HIV disease progression in postpartum women with HIV., PMID:40476693
Macrophages generated in 3D mechanical microenvironment contribute to recruiting Peritonitis-associated neutrophils in vivo., PMID:40468354
Activation of Human FPR2 with AT-RvD1 Resolves Acute Sialadenitis in Vivo., PMID:40464830
FCGR1A Alleviates Ischemic Stroke-induced Injury by Promoting Anti-Inflammatory Microglial Polarization via the AMPK-mTOR Signaling Pathway., PMID:40464505
Sanguinoderma rugosum (Agaricomycetes), a Wild Malaysian Medicinal Mushroom, Triggers Anti-Neuroinflammatory Genes Expression in LPS-Stimulated BV-2 Microglial Cells., PMID:40460400
Analysis of the inflammatory gene expression characteristics and immune microenvironment regulatory mechanisms in the testicular tissue of patients with non-obstructive azoospermia., PMID:40460050
Bacteriophage cocktail LEC2-LEC10 for broad-spectrum control of pathogenic and uncharacterized Escherichia coli in fresh produce., PMID:40458707
Enolase and 16.5-kDa Tegument-Associated Protein in Fasciola hepatica Extracellular Vesicles: Clues to Their Role in Pathogenesis., PMID:40458671
TLR4 and prostaglandin pathways at the crossroads of endotoxemia-induced lipolysis., PMID:40458405
TRAIL (DR5) receptor and the modulation of TRAIL pathway in PLWHIV: key mechanisms in the progression of HIV disease., PMID:40452022
Single-cell analyses identify monocyte gene expression profiles that influence HIV-1 reservoir size in acutely treated cohorts., PMID:40442100
Renal cancer cells acquire immune surface protein through trogocytosis and horizontal gene transfer., PMID:40440354
Prenatal Exposure to Lipopolysaccharide or Valproate Leads to Abnormal Accumulation of the NMDA Receptor Agonist D-Aspartate in the Adolescent Rat Brain., PMID:40437860
Biomarkers of intestinal permeability in major psychiatric disorders: Distinct biological roles call for a more nuanced application., PMID:40436362
Dietary Supplementation of Edible Mushroom Phallus atrovolvatus Aqueous Extract Attenuates Brain Changes in the AppNL-G-F Mouse Model of Alzheimer's Disease., PMID:40431417
Zinc Supplementation, Inflammation, and Gut Integrity Markers in HIV Infection: A Randomized Placebo-Controlled Trial., PMID:40431411
Polarized Macrophages Show Diverse Pro-Angiogenic Characteristics Under Normo- and Hyperglycemic Conditions., PMID:40429986
Persistent Monocytic Bioenergetic Impairment and Mitochondrial DNA Damage in PASC Patients with Cardiovascular Complications., PMID:40429707
Interactions of Probiotics with the Immune Cells of Patients with COVID-19 Pneumonia., PMID:40424990
Innovating Glioma Therapy Using Secretions from Umbilical Cord Mesenchymal Stem Cells to Target Homeobox and Growth Factor Genes., PMID:40421391
Highly elevated sepsis biomarkers in advanced cholangiocarcinoma without sepsis: A case report and literature review., PMID:40419900
Urotensin-II receptor contributes to the pro-inflammatory TLR4/MyD88/NF-κB/iNOS/NO pathway-mediated cardiovascular response to systemic lipopolysaccharide challenge in a septic shock model in rats., PMID:40418546
Presepsin in the amniotic fluid is a useful clinical inflammatory biomarker for the prenatal predictive diagnosis of histologic chorioamnionitis: a retrospective preliminary study., PMID:40413908
Tn antigen suppresses lipopolysaccharide-induced dermatitis via Clec10a., PMID:40412372
Synovium-on-a-Chip Reveals Fibroblast-Macrophage Crosstalk Underpinning Joint Homeostasis and Evaluation of Gout Therapies., PMID:40411870
Beneficial changes in total cholesterol, LDL-C, biomarkers of intestinal inflammation, and vitamin E status in adults with metabolic syndrome consuming almonds as snack foods: a randomized controlled clinical trial., PMID:40409246
Human macrophage pro-inflammatory polarization in response to free cholesterol and cholesterol remnants., PMID:40405534
Docosahexaenoic acid (DHA) supplementation attenuates changes in the concentration, phenotype, and response of immune peripheral blood cells in breast cancer patients undergoing neoadjuvant therapy. Secondary findings from the DHA-WIN trial., PMID:40405290
Understanding residual risk of cardiovascular disease in people with HIV., PMID:40397567
The evaluation of a novel multi-epitope vaccine against human papillomavirus and Candida albicans., PMID:40390500
Ex vivo lung perfusion with GLP-1R agonist mitigates ischemia/reperfusion injury through pyroptosis modulation in lung transplantation- an experimental study., PMID:40387728
SLC25A33-mediated mitochondrial DNA synthesis plays a critical role in the inflammatory response of M1 macrophages by contributing to mitochondrial ROS and VDAC oligomerization., PMID:40384854
Effects of Porphyromonas gingivalis lipopolysaccharide on the behavior of human dental pulp stem cells in vitro and their inflammation-related transcriptomics profile., PMID:40381466
Prospective evaluation of soluble CD14 as a biomarker following five aflibercept treatments in diabetic macular edema., PMID:40379891
Biochemical and hematological reference intervals in rhesus and cynomolgus macaques and implications for vaccine and drug development., PMID:40379874
SARS-CoV-2 induced immune perturbations in infants vary with disease severity and differ from adults' responses., PMID:40379618
For research use only. Not for human or drug use.
