Catalog No.
ARC13601
Biological activity
Measured in a cell proliferation assay using human erythroleukemic cells (TF‑1). The ED50 for this effect is 0.0500-0.200 ng/mL.
Expression system
Mammalian Cells
Species
Rattus norvegicus (Rat)
Protein length
Met20-Val132
Nature
Recombinant
Endotoxin level
<0.1 EU/μg of the protein by the LAL method.
Purity
>90% as determined by SDS-PAGE.
Accession
Q08125
Applications
Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
IL5, B-cell differentiation factor I, IL-5, T-cell replacing factor, TRF, Eosinophil differentiation factor, Interleukin-5, Drug Target
Activation of pyroptosis impairs basal cell differentiation in the nasal epithelium in chronic rhinosinusitis with nasal polyps., PMID:40511559
Repetitive ozone exposure worsens features of muco-inflammatory disease in developed Scnn1b-Tg+ mice lungs., PMID:40496925
The HL-60 clone 15 cell line as a model for leukocyte migration-possibilities and limitations., PMID:40496865
Causal Effects of Inflammatory Cytokines on Urethral Stricture Disease: A Bidirectional Mendelian Randomization Study., PMID:40491208
[Application and research progress of anti-IL-4α monoclonal antibody dupilumab in the treatment of type 2 asthma]., PMID:40491151
Amygdalin Alleviates Airway Inflammation and Remodeling in Asthma Mice: Involvement of TGF-β1/Smads Signaling Pathway., PMID:40485525
Polynucleotides Enhance Skin Barrier Function and Reduce Inflammation in a 2,4-Dinitrochlorobenzene-Induced Mouse Model of Atopic Dermatitis., PMID:40484710
The Effect of Thymic Stromal Lymphopoietin on Reflux Esophagitis., PMID:40464554
Two unique cases of eosinophilic granulomatosis with polyangiitis in childhood treated with anti-interleukin-5 therapy: infantile-onset and submandibular salivary gland involvement., PMID:40457436
ILC2 Diversity, Location, and Function in Pulmonary Disease., PMID:40454563
Suppression of Il5 and Il13 Gene Expression by Synthetic siRNA Molecules Reduces Nasal Hyperreactivity and Inflammation in a Murine Model of Allergic Rhinitis., PMID:40451198
Network pharmacology and experimental validation of inflammation inhibition by ChuanKeZhi Injection in treating asthma., PMID:40450983
Using Olink Proteomics to Identify Inflammatory Biomarkers in the Cerebrospinal Fluid in Guillain-Barré Syndrome., PMID:40443809
A pilot investigation of the impact of acute mental and physical fatigue exposure on inflammatory cytokines and state fatigue level in breast cancer survivors., PMID:40437526
Prolonged effects of adenoviral vector priming on T-cell cytokine production in heterologous adenoviral vector/mRNA COVID-19 vaccination regimens., PMID:40436912
Peritoneal membrane transport characteristics in patients undergoing peritoneal Dialysis are associated with systemic IL-8 levels., PMID:40424748
Codium fragile Extract Ameliorates Respiratory Function by Controlling Allergic Inflammation in Ovalbumin-Induced Bronchial Disorders in Mice., PMID:40422811
[A comprehensive study of Alzheimer's disease biomarkers in plasma and cerebrospinal fluid]., PMID:40420450
Yangke powder alleviates OVA-induced allergic asthma by inhibiting the PI3K/AKT/NF-κB signaling pathway., PMID:40420184
Physical and inflammatory aspects associated to respiratory sarcopenia in community-dwelling older women., PMID:40419668
Indolepropionic acid modulates the immune response in allergic rhinitis through the AKT/CEBPB/IL‑10 signaling pathway., PMID:40417918
[The characteristics and clinical values of peripheral T lymphocytic subsets and functional changes in primary biliary cholangitis]., PMID:40415623
Microarray Patch Based Transdermal Allergen Immunotherapy Prevents Gliadin-induced Anaphylaxis in a Murine Model., PMID:40414810
ITIH4 alleviates OVA-induced asthma by regulating lung-gut microbiota., PMID:40410722
The impact of Talin2, a signaling protein regulating the focal adhesion complex, on asthma., PMID:40401633
Probiotic DNA epigenetically upregulates epithelial PD-L1 via KDM5A-mediated demethylation to suppress airway allergy by inducing activated Th2 cell apoptosis., PMID:40398257
Metformin alleviates inflammatory responses in acute allergic asthma by inhibiting ILC2s function., PMID:40398255
Long-term safety and effectiveness of mepolizumab for patients with bronchial asthma in routine clinical practice in Japan - final report of special drug use investigation., PMID:40398189
Therapeutic potential of Platycodin D in allergic asthma through anti-inflammatory and anti-remodeling effects., PMID:40397997
Exosomes derived from M2 macrophages regulate airway inflammation by modulating epithelial cell proliferation and apoptosis., PMID:40390011
The potential effect of gut microbiota on the secretion of selected cytokines by human cells in vitro., PMID:40389545
Vaccination against helminth IL-33 modulators permits immune-mediated parasite ejection., PMID:40378045
Pre-existing epigenetic state and differential NF-κB activation shape type 2 immune cell responses., PMID:40367949
Drug evaluation: mepolizumab in chronic obstructive pulmonary disease., PMID:40366762
Transcriptional co-regulator OCA-B/Pou2af1 restricts Th2 differentiation., PMID:40364837
Decoding innate lymphoid cells and innate-like lymphocytes in asthma: pathways to mechanisms and therapies., PMID:40355861
Insights from bidirectional Mendelian randomization: Evaluating the influence of circulating inflammatory cytokines on prostatitis., PMID:40355178
Relation of Cytokine Profile and Antibody Values to Post-Translational Protein Modifications in Patients with Rheumatoid Arthritis (Preliminary Data)., PMID:40353964
Depemokimab in chronic rhinosinusitis with nasal polyps: A turning point or a missed opportunity?, PMID:40347936
High local type-2 inflammation is linked to response in severe asthma treated with anti-Interleukin-5 receptor., PMID:40345261
PGC-1α agonist ZLN005 ameliorates OVA-induced asthma in BALB/c mice through modulating the NF-κB-p65/NLRP3 pathway., PMID:40343297
Liujunzi Decoction Regulated Intestinal Flora Homeostasis to Relieve Lung-Gut Axis Inflammation in Asthma Flora Disorder Mice: Possibly Related to GATA3/ILC2., PMID:40342036
MiR-155 overexpression regulates Th1/Th2 balance by inhibiting BACH1 to activate Nrf-2/HO-1 signaling pathway in allergic rhinitis., PMID:40339975
Inhibitory Effects of Phellodendri Cortex Against Airway Inflammation and Hyperresponsiveness in Ovalbumin-Induced Murine Asthma Model., PMID:40333800
Correlation among ocular surface changes and systemic hematologic indexes and disease activity in primary Sjögren's syndrome: a cross-sectional study., PMID:40329232
The interplay between systemic inflammation and myopia: A bidirectional Mendelian randomization and experimental validation study., PMID:40327989
RAG suppresses group 2 innate lymphoid cells., PMID:40326866
Puriton attenuates the asthma severity in ovalbumin-induced murine model via balancing Th1/Th2 and inhibiting inflammation., PMID:40323927
Polystyrene microplastic induced airway hyper-responsiveness, and pulmonary inflammation are mitigated by bronchom treatment in murine model of lung disease., PMID:40319658
Comparative Insights on IL-5 Targeting with Mepolizumab and Benralizumab: Enhancing EGPA Treatment Strategies., PMID:40305320
For research use only. Not for human or drug use.
