Catalog No.
YHC04301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala65-Phe348
Predicted molecular weight
34.11 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P03952
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Plasma prekallikrein, KLK3, Fletcher factor, KLKB1, Kininogenin, Plasma kallikrein, PKK
Note
For research use only.
Bioinformatics analysis of key biomarkers and potential molecular mechanisms in hepatocellular carcinoma induced by hepatitis B virus., PMID:32443377
Systemic Proteome Alterations Linked to Early Stage Pancreatic Cancer in Diabetic Patients., PMID:32545216
COVID-19-Related Coagulopathy-Is Transferrin a Missing Link?, PMID:32751741
Optimizing PEG-Extended Apelin Analogues as Cardioprotective Drug Leads: Importance of the KFRR Motif and Aromatic Head Group for Improved Physiological Activity., PMID:33001648
c.451dupT in KLKB1 is common in Nigerians, confirming a higher prevalence of severe prekallikrein deficiency in Africans compared to Europeans., PMID:33073460
Centyrin ligands for extrahepatic delivery of siRNA., PMID:33601052
Genome-wide association study of cardiac troponin I in the general population., PMID:33961016
Cardiovascular Biomarkers of Obesity and Overlap With Cardiometabolic Dysfunction., PMID:34219465
The Inclusion Principles of Human Embryos in the WOW-Based Time-Lapse System: A Retrospective Cohort Study., PMID:34381419
Kallikrein augments the anticoagulant function of the protein C system in thrombin generation., PMID:34532976
Plasma Kallikrein as a Modulator of Liver Injury/Remodeling., PMID:34566641
Genetic Profile of Endotoxemia Reveals an Association With Thromboembolism and Stroke., PMID:34668383
Systematic Construction and Validation of a Prognostic Model for Hepatocellular Carcinoma Based on Immune-Related Genes., PMID:34671598
Serum KLKB1 as a Potential Prognostic Biomarker for Hepatocellular Carcinoma Based on Data-Independent Acquisition and Parallel Reaction Monitoring., PMID:34676182
Prenatal diagnosis of a 4.5-Mb deletion at chromosome 4q35.1q35.2: Case report and literature review., PMID:34794455
Prekallikrein deficiency due to homozygous KLKB1(+) mutation c.444_445insT (p.Ser151PhefsTer34)., PMID:34847617
Differential proteomic analysis demonstrates follicle fluid participate immune reaction and protein translation in yak., PMID:35031034
A review of oral kallikrein inhibitor berotralstat for hereditary angioedema., PMID:35188140
Ablation of Plasma Prekallikrein Decreases Low-Density Lipoprotein Cholesterol by Stabilizing Low-Density Lipoprotein Receptor and Protects Against Atherosclerosis., PMID:35189703
Genetics of osteopontin in patients with chronic kidney disease: The German Chronic Kidney Disease study., PMID:35385482
The Dysregulation of the Renin-Angiotensin System in COVID-19 Studied by Serum Proteomics: Angiotensinogen Increases with Disease Severity., PMID:35458690
Proteomics discovery of pulmonary hypertension biomarkers: Insulin-like growth factor binding proteins are associated with disease severity., PMID:35514776
Plasma proteomic analysis of association between atrial fibrillation, coronary microvascular disease and heart failure., PMID:35600285
Impaired Kallikrein-Kinin System in COVID-19 Patients' Severity., PMID:35812405
Searching for Genetic Biomarkers for Hereditary Angioedema Due to C1-Inhibitor Deficiency (C1-INH-HAE)., PMID:35873600
The therapeutic relevance of the Kallikrein-Kinin axis in SARS-cov-2-induced vascular pathology., PMID:35930434
[Matrix metalloproteinase 14 and plasma kallikrein 1 may be potential biomarkers in the diagnosis and treatment of sepsis: a proteomics and bioinformatics analysis]., PMID:36100402
Characterization of a proteomic profile associated with organ dysfunction and mortality of sepsis and septic shock., PMID:36459524
Prion Mutations in Republic of Republic of Korea, China, and Japan., PMID:36614069
[Analysis of differentially expressed microRNA and protein expression profiles carried by exosomes in the plasma of patients with Takayasu's arteritis]., PMID:36631039
Severe high-molecular-weight kininogen deficiency: clinical characteristics, deficiency-causing KNG1 variants, and estimated prevalence., PMID:36700498
KLKB1 and CLSTN2 are associated with HDL-mediated cholesterol efflux capacity in a genome-wide association study., PMID:36812656
PGK1 modulates balance between pro- and anti-inflammatory cytokines by interacting with ITI-H4., PMID:36841032
Circulating extracellular vesicles promote recovery in a preclinical model of intracerebral hemorrhage., PMID:37090418
Proteome-wide mendelian randomization identifies causal plasma proteins in venous thromboembolism development., PMID:37537391
Genomic selection pressure discovery using site-frequency spectrum and reduced local variability statistics in Pakistani Dera-Din-Panah goat., PMID:37750990
Biology of factor XI., PMID:37874916
Proteomics Analysis of Serum Reveals Potential Biomarkers for Heart Failure Patients with Phlegm-Blood Stasis Syndrome., PMID:38048169
Clinical Progress in Hepatic Targeting for Novel Prophylactic Therapies in Hereditary Angioedema., PMID:38142864
CRISPR-Cas9 In Vivo Gene Editing of KLKB1 for Hereditary Angioedema., PMID:38294975
Combined transcriptomics and TMT-proteomics reveal abnormal complement and coagulation cascades in cow's milk protein allergy., PMID:38457985
Identifying Potential Drug Targets for Keloid: A Mendelian Randomization Study., PMID:38797322
The trajectory of vesicular proteomic signatures from HBV-HCC by chitosan-magnetic bead-based separation and DIA-proteomic analysis., PMID:39207047
[Analysis of two consanguineous Chinese pedigrees affected with Hereditary prokallikrein deficiency and High molecular weight kininogen deficiency]., PMID:39217484
Pharmacogenomics of clinical response to Natalizumab in multiple sclerosis: a genome-wide multi-centric association study., PMID:39264442
CRISPR-Based Therapy for Hereditary Angioedema., PMID:39445704
Platform-dependent effects of genetic variants on plasma APOL1 and their implications for kidney disease., PMID:39975113
Plasma Proteomic Assessment of Calcific Aortic Valve Disease in Older Adults., PMID:40008515
Enhancement of plasma kallikrein specificity of antitrypsin variants identified by phage display and partial reversion., PMID:40075385
Potential therapeutic targets for deep vein thrombosis: A proteome-wide Mendelian randomization study., PMID:40462713
For research use only. Not for human or drug use.
