Catalog No.
RXX02141
Species reactivity
Francisella tularensis
Host species
Mouse
Isotype
IgG2a
Clonality
Monoclonal
Applications
ELISA, ICC, IF, WB
Target
LPS, Lipopolysaccharide
Specificity
There is no crossreactivity with Fr. novicida, Br. abortus, Br. suis, Br. melitensis, Br. ovis, Y. pestis, Y. enterocolitica, Y. pseudotuberculosis, E. coli, and V. cholerae.
Concentration
3.25 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Form
Liquid
Storage buffer
100 mM Pro-Ac, 20 mM Arg, pH 5.0
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
FB11
Note
For research use only.
Lipopolysaccharide microarrays for the detection of antibodies., PMID:15847798
Proteomic analysis of anti-Francisella tularensis LVS antibody response in murine model of tularemia., PMID:15892173
A novel screening ELISA and a confirmatory Western blot useful for diagnosis and epidemiological studies of tularemia., PMID:16050523
[Phase variations of Francisella tularensis lipopolysaccharide in human infection and immunization]., PMID:16146218
Seroprevalence of brucellosis, tularemia, and yersiniosis in wild boars (Sus scrofa) from north-eastern Germany., PMID:16364020
Production and characterization of a monoclonal antibody to Francisella tularensis lipopolysaccharide., PMID:17451358
[Highly sensitive enzyme-linked assay based on monoclonal antibodies for detection of Brucella antigens]., PMID:17523430
Differential effects of Francisella tularensis lipopolysaccharide on B lymphocytes., PMID:17634278
Generation and characterization of hybridoma antibodies for immunotherapy of tularemia., PMID:17764754
Immunization with heat-killed Francisella tularensis LVS elicits protective antibody-mediated immunity., PMID:17960662
Inhibition of airway eosinophilia and pulmonary pathology in a mouse model of allergic asthma by the live vaccine strain of Francisella tularensis., PMID:18307525
Native outer membrane proteins protect mice against pulmonary challenge with virulent type A Francisella tularensis., PMID:18505805
Neisseria meningitidis PorB, a Toll-like receptor 2 ligand, improves the capacity of Francisella tularensis lipopolysaccharide to protect mice against experimental tularemia., PMID:18614668
[Interaction of S- and R-lipopolysaccharides of Francisella tularensis with lypopolysaccharide-binding protein of human serum]., PMID:18819401
Francisella tularensis infection-derived monoclonal antibodies provide detection, protection, and therapy., PMID:19176692
Antigen-specific B-1a antibodies induced by Francisella tularensis LPS provide long-term protection against F. tularensis LVS challenge., PMID:19251656
[Experimental verification of a model of complement-dependent immune lysis of liposomes]., PMID:19569506
Francisella tularensis blue-gray phase variation involves structural modifications of lipopolysaccharide o-antigen, core and lipid a and affects intramacrophage survival and vaccine efficacy., PMID:21687776
Francisella tularensis suppresses the proinflammatory response of endothelial cells via the endothelial protein C receptor., PMID:20543103
Identification, characterization and immunogenicity of an O-antigen capsular polysaccharide of Francisella tularensis., PMID:20625403
Characterization of monoclonal antibodies to terminal and internal O-antigen epitopes of Francisella tularensis lipopolysaccharide., PMID:21466282
Role of TLR signaling in Francisella tularensis-LPS-induced, antibody-mediated protection against Francisella tularensis challenge., PMID:21750122
Host-adaptation of Francisella tularensis alters the bacterium's surface-carbohydrates to hinder effectors of innate and adaptive immunity., PMID:21799828
A typical preparation of Francisella tularensis O-antigen yields a mixture of three types of saccharides., PMID:22091710
Protective B-cell epitopes of Francisella tularensis O-polysaccharide in a mouse model of respiratory tularaemia., PMID:22486311
Structural analysis of a protective epitope of the Francisella tularensis O-polysaccharide., PMID:22747335
Chemical synthesis and immunological evaluation of the inner core oligosaccharide of Francisella tularensis., PMID:22867268
Natural IgM mediates complement-dependent uptake of Francisella tularensis by human neutrophils via complement receptors 1 and 3 in nonimmune serum., PMID:22888138
Antibodies to both terminal and internal B-cell epitopes of Francisella tularensis O-polysaccharide produced by patients with tularemia., PMID:24351753
Novel catanionic surfactant vesicle vaccines protect against Francisella tularensis LVS and confer significant partial protection against F. tularensis Schu S4 strain., PMID:24351755
Development of an immunosensor for the detection of Francisella tularensis antibodies., PMID:24817365
Production of anti-LPS IgM by B1a B cells depends on IL-1β and is protective against lung infection with Francisella tularensis LVS., PMID:25768794
Characterization of Francisella tularensis Schu S4 mutants identified from a transposon library screened for O-antigen and capsule deficiencies., PMID:25999917
Development of a bead-based Luminex assay using lipopolysaccharide specific monoclonal antibodies to detect biological threats from Brucella species., PMID:26438077
Virulence of representative Japanese Francisella tularensis and immunologic consequences of infection in mice., PMID:26853540
Electrochemiluminescence (ECL) immunosensor for detection of Francisella tularensis on screen-printed gold electrode array., PMID:27255102
A Pathogen-Specific Cargo Delivery Platform Based on Mesoporous Silica Nanoparticles., PMID:28437093
Defective anti-polysaccharide IgG vaccine responses in IgA deficient mice., PMID:28774562
Immunoglobulin G subclass switching impacts sensitivity of an immunoassay targeting Francisella tularensis lipopolysaccharide., PMID:29630613
Development of dual reporter imaging system for Francisella tularensis to monitor the spatio-temporal pathogenesis and vaccine efficacy., PMID:30112352
[A comparative study of experimental and commercial serological tests for detection of antibodies in humans with tularemia.]., PMID:30768885
Glycoconjugate vaccine using a genetically modified O antigen induces protective antibodies to Francisella tularensis., PMID:30872471
Inhibition of Francisella tularensis phagocytosis using a novel anti-LPS scFv antibody fragment., PMID:31388083
Development of an immunoassay test system based on monoclonal antybodies and immunomagnetic particles for the detection of F. tularensis cells., PMID:34105911
Critical role of IL-25-ILC2-IL-5 axis in the production of anti-Francisella LPS IgM by B1 B cells., PMID:34449811
Development of Immunoassays for Detection of Francisella tularensis Lipopolysaccharide in Tularemia Patient Samples., PMID:34451388
Alginate microencapsulation of an attenuated O-antigen mutant of Francisella tularensis LVS as a model for a vaccine delivery vehicle., PMID:35275912
Point-of-care vertical flow immunoassay system for ultra-sensitive multiplex biothreat-agent detection in biological fluids., PMID:36257115
Rapid Detection of Lipopolysaccharide and Whole Cells of Francisella tularensis Based on Agglutination of Antibody-Coated Gold Nanoparticles and Colorimetric Registration., PMID:36557493
Kinetics of the serological response up to one year after tularemia., PMID:36683705