Catalog No.
YHC13302
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu2-Glu93
Predicted molecular weight
12.16 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P05109
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
S100 calcium-binding protein A8, Urinary stone protein band A, MRP8, Cystic fibrosis antigen, Calprotectin L1L subunit, MRP-8, p8, Calgranulin-A, Migration inhibitory factor-related protein 8, Leukocyte L1 complex light chain, S100A8, Protein S100-A8, CAGA, CFAG
Note
For research use only.
Targeting S100A8/A9-NCF1 axis in tumor microenvironment to prevent tumor metastasis by self-assembled peptide nanofibers., PMID:40040282
Neutrophil-derived exosomal S100A8 aggravates lung injury in sepsis by inducing pyroptosis., PMID:40056630
Inflammation molecular network alterations in a depressive-like primate model., PMID:40081592
Proteomic analysis and effects on osteogenic differentiation of exosomes from patients with ossification of the spinal ligament., PMID:40098982
Extracellular vesicle-bound S100A8/A9 is differentially expressed in septic shock and prompts acute lung injury., PMID:40102943
The genetic association between major depressive disorder and coronary heart disease., PMID:40114590
Plasma Proteomic Profiles of Pediatric Patients With Human Herpesvirus 6B Encephalitis Following Umbilical Cord Blood Transplantation., PMID:40116181
Isolation of dihydroagarofuran sesquiterpene from the fruits of Tripterygium hypoglaucum and evaluation of their anti-inflammatory activity., PMID:40118309
Binding of Pro-Inflammatory Proteins S100A8 or S100A9 to Amyloid-β Peptide Suppresses Its Fibrillation., PMID:40149967
Calprotectin-mediated survival of Staphylococcus aureus in coculture with Pseudomonas aeruginosa occurs without nutrient metal sequestration., PMID:40152583
Chaihu-Shugan-San alleviates post-stroke depression in mice: Mechanistic insights into exosome-mediated neuroprotection., PMID:40154896
Chronological maturation of the skin immune barrier is topographically different., PMID:40158778
Gene expression analysis of Schizophrenia., PMID:40162448
S100 Protein Family in Lung Cancer: an Updated Narrative Review., PMID:40166494
Transcriptome Analysis of Monocytes Treated with Dengue NS1 Revealed a Shift in Transcripts Involving in Self-Propagated Proinflammation and Antiviral Responses., PMID:40166903
Association of Obesity and Innate Immune Markers With Resistance to Biologic Therapy in Psoriasis., PMID:40172874
Therapeutic S100A8/A9 inhibition reduces NADPH oxidase expression, reactive oxygen species production and NLRP3 inflammasome priming in the ischemic myocardium., PMID:40180274
Impact of atopic dermatitis on renal dysfunction: insights from patient data and animal models., PMID:40191205
Atractylenolide-I restore intestinal barrier function by targeting the S100A9/AMPK/mTOR signaling pathway., PMID:40196359
Chronic skin and systemic inflammation modulated by S100A8 and S100A9 complexes., PMID:40217087
Development of novel neutralizing single-chain fragment variable antibodies against S100A8., PMID:40221535
Identification of Crohn's Disease-Related Biomarkers and Pan-Cancer Analysis Based on Machine Learning., PMID:40224483
Reading of human acute immune dynamics in omicron SARS-CoV-2 breakthrough infection., PMID:40231451
Plasma Proteomics of the Fontan Circulation Reveal Signatures of Oxidative Stress and Cell Death., PMID:40235440
The Impact of Recreational Diving to a Depth of 40 m on Selected Intracellular DAMPs., PMID:40243713
Targeting Calprotectin S100A8/A9 to Overcome AML Progression in DNMT3A-Mutant Cells., PMID:40266434
S100A8/A9 high-expression macrophages mediate renal tubular epithelial cell damage in acute kidney injury following acute type A aortic dissection surgery., PMID:40270593
Geniposide via enema alleviates colitis by modulating intestinal flora and bile acid metabolites, inhibiting S100A8/S100A9/NF-κB, and promoting TGR5 inhibition of NLRP3 inflammasome., PMID:40279965
Neutrophil Z Is a Novel Marker to Differentiate Disease Flares From Bacterial Infections in Febrile SLE Patients., PMID:40302194
Zebrafish do not have a calprotectin ortholog., PMID:40315184
Calprotectin as a sepsis diagnostic marker in critical care: a retrospective observational study., PMID:40319081
Exhaled breath protein composition in patients hospitalised during the first wave of COVID-19., PMID:40341493
Protein Biomarkers in Venous Leg Ulcer Fluid: A Systematic Review., PMID:40342218
In vivo RNAi screen and validation reveals Ngp, Hba-a1, and S100a8 as novel inhibitory targets on T lymphocytes in liver cancer., PMID:40352930
Development and validation of an early diagnosis model for severe mycoplasma pneumonia in children based on interpretable machine learning., PMID:40361124
Generalized gingivitis-related salivary proteomic profile in pregnant women with obesity: insights into biological mechanisms assessed by Tandem Mass Spectrometry., PMID:40366920
Acute-phase proteins as biomarkers of inflammation in HIV patients with latent tuberculosis: a prospective study., PMID:40370442
Calprotectin inhibition attenuates silica-induced lung fibrosis., PMID:40381145
Leukemia cells remodel bone marrow stromal cells to generate a protumoral microenvironment via the S100A8-NOX2-ROS signaling pathway., PMID:40382430
Synergistic inhibition of CitH3 and S100A8/A9: A novel therapeutic strategy for mitigating sepsis-induced inflammation and lung injury., PMID:40390290
Genome-wide expression in human whole blood for diagnosis of latent tuberculosis infection: a multicohort research., PMID:40415930
Low-Molecular-Weight Fucoidan Inhibits Thromboinflammation and Ameliorates Deep Vein Thrombosis via Targeting S100A8/A9., PMID:40422770
Comparative Proteomic Analysis of Osteoarthritis and Rheumatoid Arthritis: Identifying Potential Biomarkers., PMID:40426329
Identification of vitronectin as a potential non-invasive biomarker of metastatic breast cancer using a label-free LC-MS/MS approach., PMID:40442728
Sea Cucumber Fucoidan Inhibits Helicobacter pylori Gastritis via MAPK/NF-κB Signaling and Gut Microbiota Modulation., PMID:40444701
Impact of obesity on proteomic profiles of follicular fluid-derived small extracellular vesicles: A comparison between PCOS and non-PCOS women., PMID:40468347
Plasma proteomics identifies S100A8/A9 as a novel biomarker and therapeutic target for fulminant myocarditis., PMID:40480626
S100a8 inhibitor Paquinimod attenuates coal dust-induced pulmonary fibrosis via blocking neutrophils-S100a8-Tlr4-macrophages signaling axis., PMID:40482449
In-silico identification and experimental validation of shared genes and pathways to decipher the molecular links between COPD and MASLD., PMID:40482557
S100A8 Mediates Autophagy and Apoptosis in Ovarian Cancer Cells via the PI3K/Akt Pathway., PMID:40485527
For research use only. Not for human or drug use.
