Catalog No.
YHC34602
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser860-Arg1231
Predicted molecular weight
44.00 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P08603
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Complement factor H, CFH, H factor 1, HF1, HF, HF2
Note
For research use only.
[Past history of obesity and immune memory in age-related macular degeneration]., PMID:39756898
The role of the complement system in Shiga toxin-associated hemolytic uremic syndrome., PMID:39792253
A mutant complement factor H (W1183R) enhances proteolytic cleavage of von Willebrand factor by ADAMTS-13 under shear., PMID:39798927
Complement regulators as novel targets for anti-cancer therapy: A comprehensive review., PMID:39826189
Exploring genetic associations and drug targets for mitochondrial proteins and schizophrenia risk., PMID:39863625
Dynamic Complement Protein Changes in Aqueous Humor and Plasma of Patients With Retinal Vein Occlusion During Ranibizumab Treatment., PMID:39906134
Hypothermia regulates mitophagy and apoptosis via PINK1/Parkin-VDAC 3 signaling pathway during oxygen-glucose deprivation/recovery injury., PMID:39920327
Ocular Localization of Complement Factor H and Its Association with Diseases in the Eye., PMID:39930234
The interactions between ARMS2, CFH, VEGF-A and environmental factors on the risk of age-related macular degeneration., PMID:39959171
Biosensor characterization: formal methods from the perspective of proteome fractions., PMID:39959635
The AMD-associated genetic polymorphism CFH Y402H confers vulnerability to Hydroquinone-induced stress in iPSC-RPE cells., PMID:39981241
Elevated Plasma Complement Factors in CRB1-Associated Inherited Retinal Dystrophies., PMID:39982393
Contribution of cuproptosis and immune-related genes to idiopathic pulmonary fibrosis disease., PMID:39991151
Human Factor H and anti-Neisserial surface protein A (NspA) antibodies compete for overlapping binding sites on meningococcal NspA., PMID:39992115
Multiplex PCR-Mass Spectrometry Mini-Sequencing Technology Detected Antibiotic Resistance of Helicobacter pylori to Six Antibiotics., PMID:40004094
A tumor-binding antibody with cross-reactivity to viral antigens., PMID:40009215
Machine learning approach on plasma proteomics identifies signatures associated with obesity in the KORA FF4 cohort., PMID:40017018
Porcine Sub-Retinal Pigment Epithelium Deposits: A Model for Dry Age-Related Macular Degeneration With Comparison to Human Drusen., PMID:40048184
Genetic Distinctions Between Reticular Pseudodrusen and Drusen: A Genome-Wide Association Study., PMID:40064387
Azole resistance: insights from Y132 substitutions in Candida sterol 14α-demethylase utilizing molecular dynamics simulations., PMID:40091806
Identification of the Hub Gene LDB3 in Stanford Type A Aortic Dissection Based on Comprehensive Bioinformatics Analysis., PMID:40099963
CRISPR targeting of SNPs associated with age-related macular degeneration in ARPE-19 cells: a potential model for manipulating the complement system., PMID:40102632
Common Haplotypes within the Chromosome 1q31.3 Region Determine Systemic Concentrations of the Entire Complement Factor H Protein Family., PMID:40139172
Glomerular mesangial cells derived complement factor H regulates complement activation, influences cell proliferation, and maintains actin cytoskeleton., PMID:40157080
The sialome of the retina, alteration in age-related macular degeneration (AMD) pathology and potential impacts on Complement Factor H., PMID:40161805
Proteomic Analysis of 442 Clinical Plasma Samples From Individuals With Symptom Records Revealed Subtypes of Convalescent Patients Who Had COVID-19., PMID:40207927
Circulating extracellular vesicles protein expression for early prediction of platinum-resistance in high-grade serous ovarian cancer., PMID:40210758
Moss-derived human complement factor H modulates retinal immune response and attenuates retinal degeneration., PMID:40217267
Genotypes of SNPs of key genes regulate susceptibility and drug sensitivity to neovascular AMD in the human population., PMID:40221144
An optimized luciferin formulation for NanoLuc-based in vivo bioluminescence imaging., PMID:40234651
Protective Vaccination of Mice Against Blood-Stage Malaria Impacts Hepatic Expression of Genes Encoding Acute-Phase Proteins and IL-6 Family Members., PMID:40243929
Rare predicted loss-of-function and damaging missense variants in CFHR5 associate with protection from age-related macular degeneration., PMID:40250423
Long-term GABA supplementation mitigates anxiety by modulating complement and neuroinflammatory pathways., PMID:40274802
Comprehensive analysis of blood proteome response to necrotic enteritis in broiler chicken., PMID:40275387
NETs-related genes predict prognosis and are correlated with the immune microenvironment in osteosarcoma., PMID:40276062
Proteomic and In Silico Analyses Highlight Complement System's Role in Bladder Cancer Immune Regulation., PMID:40283026
Truncated complement factor H Y402 gene therapy rescues C3 glomerulonephritis., PMID:40285355
Gene mutations and differentiation in laryngeal and pharyngeal squamous cell carcinoma., PMID:40293562
Mutational status of RAS, SMAD4 and APC predicts survival after resection of colorectal liver metastases in Chinese patients: prognostic stratification based on genetic sequencing data of multiple somatic genes., PMID:40301949
Prediction of Interspecies Translation for Targeting Delivery Coefficients of GalNAc-siRNA Silencing Apolipoprotein C-III Using a Mechanistic Minimal Physiologically Based Pharmacokinetic/Pharmacodynamic Model., PMID:40317426
Chemokine System Changes Drive Age-Related Macular Degeneration and Influence Treatment Outcomes., PMID:40327010
Target complement factor H / serum amyloid a signaling in trichloroethylene-induced immune kidney injury., PMID:40373713
Oxidized Cell-Free Hemoglobin Induces Mitochondrial Dysfunction by Activation of the Mitochondrial Permeability Transition Pore in the Pulmonary Microvasculature., PMID:40394906
Differential analysis of core complement components expression and localization across rodent, non-human primate, and human ocular tissues., PMID:40419209
Evaluation of immune-related parameters in acellular and cellular fractions in male and female of Atlantic blue crabs (Callinectes sapidus)., PMID:40425106
In Silico Analysis of Novel circRNA-miRNA-mRNA Axis in BRAFV600E Melanoma: Implications for Primary to Metastasis Transformation and TIME Modulation., PMID:40436810
Select azo compounds post-translationally modulate HTRA1 abundance and activity potentially through interactions at the trimer interface., PMID:40463243
KLF15 deficiency contributes complement activation and podocyte injury in IgA nephropathy via regulating p300/ NF-κB axis., PMID:40466801
Explosive tumor growth in a patient with colon cancer is associated with reduced neoantigen levels and decreased interferon-gamma (IFN-γ) signaling., PMID:40474074
CD70 CAR-T cells empowered by TS-2021 through ex vivo transduction show potent antitumor efficacy against glioblastoma., PMID:40474210
For research use only. Not for human or drug use.
