Catalog No.
EHB92502
Expression system
Mammalian cells
Species
Homo sapiens (Human)
Protein length
[Met1-Ser116] & [Met1-Glu129]
Predicted molecular weight
20.64 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P01215 & P01225
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Follicle-stimulating hormone alpha chain, Lutropin alpha chain, Thyrotropin alpha chain, Follitropin alpha chain, Luteinizing hormone alpha chain, Thyroid-stimulating hormone alpha chain, FSH-alpha, LSH-alpha, Glycoprotein hormones alpha chain, CGA, TSH-alpha, Choriogonadotropin alpha chain, Anterior pituitary glycoprotein hormones common subunit alpha, CG-alpha, Chorionic gonadotrophin subunit alpha
Note
For research use only.
Neuroendocrine cells in Drosophila melanogaster producing GPA2/GPB5, a hormone with homology to LH, FSH and TSH., PMID:21118692
Development of Selective LH Receptor Agonists by Heterodimerization with a FSH Receptor Antagonist., PMID:24900256
Receptor specificity and functional comparison of recombinant sea bass (Dicentrarchus labrax) gonadotropins (FSH and LH) produced in different host systems., PMID:21293031
The synthesis and secretion of inhibins., PMID:21353880
A dileucine determinant in the carboxyl terminal sequence of the LHβ subunit is implicated in the regulated secretion of lutropin from transfected GH3 cells., PMID:21458524
Transcription factor NF-κB (p50/p50, p65/p65) controls porcine ovarian cells functions., PMID:21996578
Serum anti-Müllerian hormone as a predictive marker of polycystic ovarian syndrome., PMID:22114521
Transcriptional silencing of the inhibin-α gene in human gastric carcinoma cells., PMID:22581369
Production of recombinant orange-spotted grouper (Epinephelus coioides) follicle-stimulating hormone (FSH) in single-chain form and dimer form by Pichia pastoris and their biological activities., PMID:22684083
Evidence for activity-regulated hormone-binding cooperativity across glycoprotein hormone receptor homomers., PMID:22893131
lGnRH-III -- a promising candidate for anticancer drug development., PMID:23016589
Regulatory processes governing the cell surface expression of LH and FSH receptors., PMID:23161136
Effect of sialylation and complexity of FSH oligosaccharides on inhibin production by granulosa cells., PMID:23166369
Modern methods to investigate the oligomerization of glycoprotein hormone receptors (TSHR, LHR, FSHR)., PMID:23351750
Relationship between mean platelet volume and low-grade systemic coagulation with vitamin D deficiency in primary ovarian insufficiency., PMID:23377179
A novel carboxyl-terminal heptapeptide initiates the regulated secretion of LH from unique sub-domains of the ER., PMID:23734233
Active immunization against GnRH reduces the synthesis of GnRH in male rats., PMID:24084232
Effect of immunization against GnRH on hypothalamic and testicular function in rams., PMID:25433833
Inhibin Biosynthesis and Activity Are Limited by a Prodomain-Derived Peptide., PMID:25961838
Active immunization with GnRH-tandem-dimer peptide in young male rats reduces serum reproductive hormone concentrations, testicular development and spermatogenesis., PMID:26208395
Activins in reproductive biology and beyond., PMID:26884470
A human FSHB transgene encoding the double N-glycosylation mutant (Asn(7Δ) Asn(24Δ)) FSHβ subunit fails to rescue Fshb null mice., PMID:26911932
Physiological interactions between the hypothalamic-pituitary-gonadal axis and spleen in rams actively immunized against GnRH., PMID:27322522
c-JUN Dimerization Protein 2 (JDP2) Is a Transcriptional Repressor of Follicle-stimulating Hormone β (FSHβ) and Is Required for Preventing Premature Reproductive Senescence in Female Mice., PMID:28007961
Role of FSH glycan structure in the regulation of Sertoli cell inhibin production., PMID:28855248
Construction and expression of vectors encoding biologically active rodent gonadotropins., PMID:29033405
Active-site plasticity revealed in the asymmetric dimer of AnPrx6 the 1-Cys peroxiredoxin and molecular chaperone from Anabaena sp. PCC 7210., PMID:29215017
Gonadotropins and their receptors: coevolution, genetic variants, receptor imaging, and functional antagonists., PMID:29462242
Study of anti-Müllerian hormone levels in patients with Myotonic Dystrophy Type 1. Preliminary results., PMID:29770362
HIF involvement in the regulation of rat Sertoli cell proliferation by FSH., PMID:29859192
Activin A in Mammalian Physiology., PMID:30540228
Structure-Function Relationships of the Follicle-Stimulating Hormone Receptor., PMID:30555414
Are there differences in basal thrombophilias and C-reactive protein between women with or without PCOS?, PMID:31023609
Commentary on the Recent FSH Collection: Known Knowns and Known Unknowns., PMID:31865385
'Free' inhibin α subunit is expressed by bovine ovarian theca cells and its knockdown suppresses androgen production., PMID:31874971
Engineering the Ovarian Hormones Inhibin A and Inhibin B to Enhance Synthesis and Activity., PMID:32569368
Loss of Inhibin Advances Follicle Activation and Female Puberty Onset but Blocks Oocyte Maturation in Zebrafish., PMID:33045050
Structural analysis of the impact of a novel androgen receptor gene mutation in two adult patients with mild androgen insensitivity syndrome., PMID:33108824
Crystal Structure of Human APPL BAR-PH Heterodimer Reveals a Flexible Dimeric BAR curve: Implication in Mutual Regulation of Endosomal Targeting., PMID:33258922
Membrane Estrogen Receptor (GPER) and Follicle-Stimulating Hormone Receptor (FSHR) Heteromeric Complexes Promote Human Ovarian Follicle Survival., PMID:33299978
Actions and Roles of FSH in Germinative Cells., PMID:34576272
The effect of interleukin-6 level at the time of hospitalisation on erectile functions in hospitalised patients with COVID-19., PMID:34687052
Human INHBB Gene Variant (c.1079T>C:p.Met360Thr) Alters Testis Germ Cell Content, but Does Not Impact Fertility in Mice., PMID:35022746
Novel bone morphogenetic protein 15 (BMP15) gene variants implicated in premature ovarian insufficiency., PMID:35232444
Genetic analysis of activin/inhibin β subunits in zebrafish development and reproduction., PMID:36469526
Rerouting of follicle-stimulating hormone secretion and gonadal function., PMID:36496082
Activating Transcription Factor 3 Stimulates Follicle-Stimulating Hormone-β Expression In Vitro But Is Dispensable for Follicle-Stimulating Hormone Production in Murine Gonadotropes In Vivo., PMID:36951304
Galanin-like peptide and its correlation with androgen levels in patients with polycystic ovary syndrome., PMID:37155301
An mRNA-based platform for the delivery of pathogen-specific IgA into mucosal secretions., PMID:37918405
Structural and evolutionary insights into the functioning of glycoprotein hormones and their receptors., PMID:39871527
For research use only. Not for human or drug use.
