Catalog No.
YHB95601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala117-Ser269
Predicted molecular weight
18.3 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P01584
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Interleukin-1 beta, IL1B, Catabolin, IL1F2, IL-1 beta,IL-1β
Interleukin-1β in circulating mononuclear cells predicts steatotic liver disease improvement after weight loss in subjects with obesity and prediabetes or type 2 diabetes., PMID:40514652
Activation of pyroptosis impairs basal cell differentiation in the nasal epithelium in chronic rhinosinusitis with nasal polyps., PMID:40511559
Endoplasmic reticulum stress sensor protein PERK in hepatic stellate cells promotes the progression of hepatocellular carcinoma via p38δ MAPK/IL-1β axis., PMID:40481076
Alternative Combinations of IL17A Polymorphic Variants with the Variants of TNF, IL1B, IL6, and IL8 Proinflammatory Cytokines Genes in Uterine Leiomyoma., PMID:40448881
The Gut Microbial Metabolite Butyrate Alleviates IL-1β-Induced Mitochondrial Dysfunction and Oxidative Stress in Pancreatic Islets., PMID:40444526
Single-cell analyses identify monocyte gene expression profiles that influence HIV-1 reservoir size in acutely treated cohorts., PMID:40442100
Exploring the Epidemiology and Molecular Mechanisms of Riboflavin Against Chronic Kidney Disease Based on Data Mining, Single-Cell RNA Sequencing and Molecular Docking., PMID:40435123
Activation of the NALP3-CASP1-IL-1 β Inflammatory Pathway by Pesticide Exposure in Human Umbilical Vein Endothelial Cells., PMID:40430087
Rapid Reduction of Pro-Inflammatory Cytokines with an Oral Topical Composition Comprising Olive Oil, Trimethylglycine and Xylitol: A Randomized Double-Blind Controlled Trial., PMID:40430061
Proteomic Analysis of Invasive Breast Cancer Cells Treated with CBD Reveals Proteins Associated with the Reversal of Their Epithelial-Mesenchymal Transition Induced by IL-1β., PMID:40429863
Sulfasalazine combined with anti-IL-1β mAb induces ferroptosis and immune modulation in oral squamous cell carcinoma., PMID:40425823
C-reactive protein conformations and their association with the IL-1β/IL-6 pathway in ocular inflammatory conditions., PMID:40421028
Alyssin Modulates Inflammatory Mediators Expression in Interleukin-1β-Stimulated Human Periodontal Ligament Cells., PMID:40384003
Deoxynivalenol induces pyroptosis and IL-1β secretion via P2X7R signal in murine RAW264.7 macrophages., PMID:40381923
Disruption of the caspase-1/IL-1β axis alleviates myocardial Ischemia/Reperfusion injury via improvement of mitochondrial homeostasis and reduction of Pyroptosis., PMID:40373207
Interleukins 10 and 1β gene polymorphisms in ischemic stroke risk in the Egyptian population., PMID:40369205
Correlation between MRNA IL1Β and type, duration of infertility in women with endometriosis on the stage preparing to assisted reproductive technologies using probiotics., PMID:40367468
The NFE2L2 (NRF2) transcription factor controls genes involved in the oxidative stress response and inflammation in myometrial cells., PMID:40360022
Chromatin accessibility profiling of Treg cells in acute urticaria., PMID:40355834
Pentraxin 3 promotes the expression of pro-inflammatory cytokines and the migration of macrophages in myocarditis., PMID:40335910
Nlrc4 Inflammasome Expression After Acute Myocardial Infarction in Rats., PMID:40332346
A pilot study on the effect of SARS-CoV-2 spike protein on IL-1β-mediated inflammation in peripheral blood immune cells from AIED patients., PMID:40329195
GPR40 inhibits microglia-mediated neuroinflammation via the NLRP3/IL-1β/glutaminase pathway after subarachnoid hemorrhage., PMID:40318813
Link N Directly Targets IL-1β to Suppress Inflammation and Regulate Sensory Pain in Intervertebral Disc Degeneration., PMID:40305345
Quantitative chest computed tomography in chronic obstructive pulmonary disease: assessing the role of emphysema severity and its correlation with clinical characteristics, lung function, and plasma levels of VEGF and IL-1β., PMID:40298164
Production of IL-1β and IL-10 by Blood Cells of Rats before and One Month after Sublethal Hypoxic Exposure in a Decompression Chamber., PMID:40295440
[Tuihuang Mixture improves α‑naphthylisothiocyanate-induced cholestasis in rats by inhibiting NLRP3 inflammasomes via regulating farnesoid X receptor]., PMID:40294921
Levels of IL-1β, MMP-8, and MMP-9 in the Saliva of Subjects With Periodontitis: A Systematic Review and Meta-Analysis., PMID:40289477
Identification of mitophagy-related genes in patients with acute myocardial infarction., PMID:40287718
Role of Salivary Biomarkers IL-1β and MMP-8 in Early Detection and Staging of Periodontal Disease., PMID:40283051
IL-17A-producing NKp44(-) group 3 innate lymphoid cells accumulate in Familial Adenomatous Polyposis duodenal tissue., PMID:40280932
P62 inhibits IL-1β release during Salmonella Typhimurium infection of macrophages., PMID:40276384
Interleukin-1β Inhibits Ovarian Cancer Cell Proliferation and Metastasis Through the MAPK/MMP12 Pathway., PMID:40244135
Associations of Gla-rich protein and interleukin-1β with coronary artery calcification risk in patients with suspected coronary artery disease., PMID:40241989
Exploring the prospective association of serum interleukin-1β and brain-derived neurotrophic factor with antidepressant treatment response., PMID:40222150
UCP1 prevents the formation of thoracic aortic aneurysms and dissection by inhibiting the TLR4/NLRP3/IL-1β signaling pathway and VSMC phenotype switching in mice., PMID:40216265
The relationship between ghrelin, epilepsy-related inflammatory biomarkers (IL-1β, IL-1R1, HMGB1), and drug-resistant epilepsy in children., PMID:40185046
The synergistic effects of prostaglandin and IL-1β on myometrial and cervical stromal cells at the onset of labor., PMID:40184914
Involvement of the NLRP3/IL-1β pathway in activation and effector functions of γδT17 cells in patients with ulcerative colitis., PMID:40182600
IL-1β inhibition in stabilizing atherosclerotic plaques: The critical role of fibroblast-like cells., PMID:40180256
TPL2 kinase activity is required for Il1b transcription during LPS priming but dispensable for NLRP3 inflammasome activation., PMID:40170849
MiR-455-5p Mitigates Interleukin-1 β-induced Chondrocyte Damage Linked to Osteoarthritis by Targeting TNFAIP8., PMID:40170451
Interleukin-1 beta and Interleukin-6 serum concentrations correlate with neuropathy and liver enzyme levels in patients diagnosed with alcohol use disorder., PMID:40168746
Dapansutrile mitigates concanavalin A- induced autoimmune hepatitis: Involvement of NLRP3/IL-1β and JNK/ p38 MAPK pathways., PMID:40164046
IMMUNE RESPONSE OF CULTURED MONOCYTES OF ATHEROSCLEROTIC PATIENTS RECEIVING STATIN THERAPY., PMID:40159269
Photobiomodulation regulates inflammation and autophagy in spinal cord injury through NLRP3/Caspase-1/IL-1β pathway by targeting TLR2., PMID:40157277
Exosomes derived from myelodysplastic syndromes cells induce IL-1β production from macrophages to promote disease progress., PMID:40147377
Noradrenaline Synergistically Enhances Porphyromonas gingivalis LPS and OMV-Induced Interleukin-1β Production in BV-2 Microglia Through Differential Mechanisms., PMID:40141302
High-dose vitamin D supplementation in pregnancy ameliorates obesity-induced increase in maternal IL-1β level without affecting obesity-induced increase in IL-6 and MCP., PMID:40139536
SOAT1 Activates NLRP3 Inflammasome to Promote Cancer-Related Lymphangiogenesis and Metastasis via IL-1β/IL-1R-1 Axis in Oral Squamous Cell Carcinoma., PMID:40135589
For research use only. Not for human or drug use.
