Catalog No.
YHB95301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met22-Asn187
Predicted molecular weight
22.19 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P01574
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
IFNB, IFN-beta, Interferon beta, IFNB1, Fibroblast interferon, IFB
MAPK15 Prevents IFNB1 Expression by Suppressing Oxidative Stress-Dependent Activation of the JNK-JUN Pathway., PMID:40507959
HERC5 induces podocyte injury in LN by mediated IRF3 ISGylation to promote the production and overactivation of IFN-β in podocytes., PMID:40505230
SP140-RESIST pathway regulates interferon mRNA stability and antiviral immunity., PMID:40500448
[Cucurbitacin B alleviates skin lesions and inflammation in a psoriasis mouse model by inhibiting the cGAS-STING signaling pathway]., PMID:40415622
Unveiling EXOC4/SEC8: a key player in enhancing antiviral immunity by inhibiting the FBXL19-STING1-SQSTM1 signaling axis., PMID:40413753
Anti-SARS-CoV-2 Small Molecule Targeting of Oxysterol-Binding Protein (OSBP) Activates Cellular Antiviral Innate Immunity., PMID:40255103
Immune regulation by the SUMO family., PMID:40108400
The SP140-RESIST pathway regulates interferon mRNA stability and antiviral immunity., PMID:39974928
Casein Glycomacropeptide Regulates Gene Expression in Intestinal Epithelial Cells: Effect of Simulated Gastrointestinal Digestion and Peptide Microencapsulation., PMID:39921639
The cellular response of lipopolysaccharide-induced inflammation in keratoconus human corneal fibroblasts to RB-PDT: Insights into cytokines, chemokines and related signaling pathways., PMID:39869570
Expression of Toll-like Receptor Genes and Antiviral Cytokines in Macrophage-like Cells in Response to Indole-3-carboxylic Acid Derivative., PMID:39599833
The 4EHP-mediated translational repression of cGAS impedes the host immune response against DNA viruses., PMID:39560640
Use of optimized single-cell RNA flow cytometry protocol identifies monocytes as main producers of type I interferon in mouse syngeneic tumors., PMID:39372774
Cytosolic nucleic acid sensors and interferon beta-1 activation drive radiation-induced anti-tumour immune effects in human pancreatic cancer cells., PMID:39372406
Junctophilin-2 is a double-stranded RNA-binding protein that regulates cardiomyocyte-autonomous innate immune response., PMID:39317111
A Hirsutella sinensis Alcohol Extract Exerts Bidirectional Immunoregulatory Effects by Regulating Macrophage Polarization., PMID:39253862
ATF3 coordinates the survival and proliferation of cardiac macrophages and protects against ischemia-reperfusion injury., PMID:39195894
Colonization Mediated by T6SS-ClpV Disrupts Host Gut Microbiota and Enhances Virulence of Salmonella enterica serovar Typhimurium., PMID:39161106
Unraveling Novel Strategies: Targeting Miz1 for Degradation to Enhance Antiviral Defense against Influenza A Virus., PMID:39086612
GATA2 promotes castration-resistant prostate cancer development by suppressing IFN-β axis-mediated antitumor immunity., PMID:39068217
Repression of mRNA translation initiation by GIGYF1 via disrupting the eIF3-eIF4G1 interaction., PMID:39018414
Type I Interferon Activates PD-1 Expression through Activation of the STAT1-IRF2 Pathway in Myeloid Cells., PMID:38995014
Molecular Events in Immune Responses to Sublingual Influenza Vaccine with Hemagglutinin Antigen and Poly(I:C) Adjuvant in Nonhuman Primates, Cynomolgus Macaques., PMID:38932372
Respiratory Virus-Induced PARP1 Alters DC Metabolism and Antiviral Immunity Inducing Pulmonary Immunopathology., PMID:38932202
Ionizing Radiation-treated NRF2-deficient Cancer Cells Promote Type I Interferon Signaling in Immune Cells., PMID:38821598
Loss of RBM45 inhibits breast cancer progression by reducing the SUMOylation of IRF7 to promote IFNB1 transcription., PMID:38797234
Meta-DHGNN: method for CRS-related cytokines analysis in CAR-T therapy based on meta-learning directed heterogeneous graph neural network., PMID:38546326
Mycobacterium tuberculosis-dependent monocyte expression quantitative trait loci, cytokine production, and TB pathogenesis., PMID:38515745
Apigenin Suppresses Innate Immune Responses and Ameliorates Lipopolysaccharide-Induced Inflammation via Inhibition of STING/IRF3 Pathway., PMID:38480499
PADI4 negatively regulates RIG-I-mediated antiviral response through deacetylation of IFN-β promoter via HDAC1., PMID:38382623
Systems genetics of influenza A virus-infected mice identifies TRIM21 as a critical regulator of pulmonary innate immune response., PMID:38331257
Identification of pattern recognition receptor genes in peripheral blood mononuclear cells and monocytes as biomarkers for the diagnosis of lupus nephritis., PMID:38228224
ω-3PUFAs Inhibit Hypoxia-Induced Retinal Neovascularization via Regulating Microglial Pyroptosis through METTL14-Mediated m6A Modification of IFNB1 mRNA., PMID:38175416
Anti-Inflammatory Ergosteroid Derivatives from the Coral-Associated Fungi Penicillium oxalicum HL-44., PMID:38067514
The nuclear receptor Nurr1 is preferentially expressed in human pro-inflammatory macrophages and limits their inflammatory profile., PMID:38066638
RNF138 Downregulates Antiviral Innate Immunity by Inhibiting IRF3 Activation., PMID:38003298
Deacetylation of ATG7 drives the induction of macroautophagy and LC3-associated microautophagy., PMID:37999993
Construction and evaluation of a novel prognostic risk model of aging-related genes in bladder cancer., PMID:37994343
IFIT3 inhibits Epstein-Barr virus reactivation via upregulating innate immunity., PMID:37994186
AGC kinase inhibitors regulate STING signaling through SGK-dependent and SGK-independent mechanisms., PMID:37939709
An IKBKE variant conferring functional cGAS/STING pathway deficiency and susceptibility to recurrent HSV-2 meningitis., PMID:37937644
Anti-Inflammatory and Analgesic Effects and Potential Targets of Shenzhu Jiedu Granule Against Novel Coronavirus Pneumonia Based on Network Pharmacology., PMID:37883768
Modeling the Immune Response for Pathogenic and Nonpathogenic Orthohantavirus Infections in Human Lung Microvasculature Endothelial Cells., PMID:37766212
The SARS-CoV-2 protein NSP2 enhances microRNA-mediated translational repression., PMID:37732428
BCR-ABL1-driven exosome-miR130b-3p-mediated gap-junction Cx43 MSC intercellular communications imply therapies of leukemic subclonal evolution., PMID:37554265
Down-regulation of stimulator of interferon genes (STING) expression and CD8+ T-cell infiltration depending on HER2 heterogeneity in HER2-positive gastric cancer., PMID:37542528
System Biology Approach to Identify the Hub Genes and Pathways Associated with Human H5N1 Infection., PMID:37515084
SARS-CoV-2 nonstructural protein 6 triggers endoplasmic reticulum stress-induced autophagy to degrade STING1., PMID:37482689
NLRP9 involved in antiviral innate immunity via binding VIM in IPEC-J2 cells., PMID:37473827
A Transcriptome Array-Based Approach Links Proteinuria and Distinct Molecular Signatures to Intrarenal Expression of Type I Interferon IFNA5 in Lupus Nephritis., PMID:37445814
For research use only. Not for human or drug use.
