Catalog No.
DGK80502
Expression system
Mammalian cells
Species reactivity
General
Host species
Mouse
Isotype
IgG2a (Need Ca2+)
Target
S1P, Sphingosine-1-phosphate
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
LT1002
Inhibition of sphingosine 1-phosphate protects mice against chondrocyte catabolism and osteoarthritis., PMID:34144150
Inflammatory Conditions Disrupt Constitutive Endothelial Cell Barrier Stabilization by Alleviating Autonomous Secretion of Sphingosine 1-Phosphate., PMID:32290092
Sphingosine-1-phosphate signalling drives an angiogenic transcriptional programme in diffuse large B cell lymphoma., PMID:31097785
Role of Sphingosine-1-Phosphate in Transplant Vasculopathy Evoked by Anti-HLA Antibody., PMID:25930666
Neutralizing S1P inhibits intratumoral hypoxia, induces vascular remodelling and sensitizes to chemotherapy in prostate cancer., PMID:25915662
Anti-S1P Antibody as a Novel Therapeutic Strategy for VEGFR TKI-Resistant Renal Cancer., PMID:25589614
Osteoblast-derived sphingosine 1-phosphate to induce proliferation and confer resistance to therapeutics to bone metastasis-derived prostate cancer cells., PMID:24768038
Sphingosine 1-phosphate mediates hyperalgesia via a neutrophil-dependent mechanism., PMID:23372844
Communication between host organism and cancer cells is transduced by systemic sphingosine kinase 1/sphingosine 1-phosphate signalling to regulate tumour metastasis., PMID:22707406
Local inactivation of sphingosine 1-phosphate in lymph nodes induces lymphopenia., PMID:21289303
Erythrocytes serve as a reservoir for cellular and extracellular sphingosine 1-phosphate., PMID:20186882
For research use only. Not for human or drug use.
