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Research Grade Anti-LPA/Lysophosphatidic acid Antibody (504B3)

Catalog #:   DHC33403 Specific References (49) DATASHEET
Host species: Mouse
Isotype: IgG2a
Applications: Research Grade Biosimilar
Expression system: Mammalian cells
Overview

Catalog No.

DHC33403

Expression system

Mammalian cells

Species reactivity

General

Host species

Mouse

Isotype

IgG2a

Target

lysobisphosphatidic acid, LBPA, LPA

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

CAS: 1246303-12-7

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Data Image
References

Engineering an alkaline-stable protein A through rational design strategies., PMID:40367905

Development of a fully automated latex-enhanced immunoturbidimetric method for quantitative serum Lp(a) measurement., PMID:40045089

Lipoprotein(a) as a Pharmacological Target: Premises, Promises, and Prospects., PMID:39928714

The path of GPR87: from a P2Y-like receptor to its role in cancer progression., PMID:39641798

The German Lipoprotein Apheresis Registry-Summary of the eleventh annual report., PMID:39342791

Advances in nucleic acid-targeted therapies for cardiovascular disease prevention., PMID:38970537

Lysophosphatidic acid promotes ESCC progression by increasing the level of CCL2 secreted by esophageal epithelial cells., PMID:38837511

Targeting AQP9 enhanced the anti-TNF therapy response in Crohn's disease by inhibiting LPA-hippo pathway., PMID:38583685

The importance of LDL-C lowering in atherosclerotic cardiovascular disease prevention: Lower for longer is better., PMID:38576462

Treatment with lysophosphatidic acid improves glomerulonephritis through the suppression of macrophage activation in a murine model of systemic lupus erythematosus., PMID:38436267

The impacts of biologic treatment on metabolic profiling in psoriasis., PMID:38284208

Autotaxin inhibitor IOA-289 reduces gastrointestinal cancer progression in preclinical models., PMID:37550785

Established and Emerging Lipid-Lowering Drugs for Primary and Secondary Cardiovascular Prevention., PMID:37486464

Inclisiran, Low-Density Lipoprotein Cholesterol and Lipoprotein (a)., PMID:37111334

Lysophospholipids and their producing enzymes: Their pathological roles and potential as pathological biomarkers., PMID:37061204

Prostate cancer cell-platelet bidirectional signaling promotes calcium mobilization, invasion and apoptotic resistance via distinct receptor-ligand pairs., PMID:36806315

The prognostic activity of acylglycerol kinase immunohistochemical expression in colon adenocarcinoma patients., PMID:38572459

Decrease in serum levels of autotaxin in COVID-19 patients., PMID:36369824

Long-Term Blockade of Nociceptive Nav1.7 Channels Is Analgesic in Rat Models of Knee Arthritis., PMID:36358921

New Strategies for Lowering Low Density Lipoprotein Cholesterol for Cardiovascular Disease Prevention., PMID:36213094

Hepatocyte-Secreted Autotaxin Exacerbates Nonalcoholic Fatty Liver Disease Through Autocrine Inhibition of the PPARα/FGF21 Axis., PMID:35931383

Non-Lipid Effects of PCSK9 Monoclonal Antibodies on Vessel Wall., PMID:35806908

Pain-like behavior in the collagen antibody-induced arthritis model is regulated by lysophosphatidic acid and activation of satellite glia cells., PMID:35026421

Aberrant ENPP2 expression promotes tumor progression in multiple myeloma., PMID:34847837

Generation of an Lpar1-EGFP Fusion Knock-in Transgenic Mouse Line., PMID:34652685

Working towards full eradication of lipid-driven cardiovascular risk?, PMID:34279797

Gintonin influences the morphology and motility of adult brain neurons via LPA receptors., PMID:34025133

Lysophosphatidic acid (LPA)-antibody (504B3) engagement detected by interferometry identifies off-target binding., PMID:33853612

Effects of topical TGF-β1, TGF-β2, ATX, and LPA on IOP elevation and regulation of the conventional aqueous humor outflow pathway., PMID:33633440

Lysophosphatidic Acid Is an Inflammatory Lipid Exploited by Cancers for Immune Evasion via Mechanisms Similar and Distinct From CTLA-4 and PD-1., PMID:33584637

Antibodies Against Lysophosphatidic Acid Protect Against Blast-Induced Ocular Injuries., PMID:33384658

New Trends in Dyslipidemia Treatment., PMID:33177309

Antigenic and Substrate Preference Differences between Scorpion and Spider Dermonecrotic Toxins, a Comparative Investigation., PMID:33019554

Lysophosphatidic acid induces tumor necrosis factor-alpha to regulate a pro-inflammatory cytokine network in ovarian cancer., PMID:32851734

Differential anatomical and cellular expression of lysophosphatidic acid receptor 1 in adult mouse brain., PMID:32718668

Biotechnology Approaches for the Treatment of Dyslipidemia., PMID:32519066

Lipid lowering therapy in cardiovascular disease: From myth to molecular reality., PMID:32492513

Metabolic effects of PCSK9 inhibition with Evolocumab in subjects with elevated Lp(a)., PMID:32393252

Nucleic Acid-Based Therapies for Atherosclerosis., PMID:32034521

Ectonucleotide pyrophosphatase 2 (ENPP2) plays a crucial role in myogenic differentiation through the regulation by WNT/β-Catenin signaling., PMID:31805399

Role of angiogenesis in adenomyosis-associated abnormal uterine bleeding and subfertility: a systematic review., PMID:31504506

Looking at Lp(a) and Related Cardiovascular Risk: from Scientific Evidence and Clinical Practice., PMID:31350625

The Future of Lipid-lowering Therapy., PMID:31340607

Lysolipid receptor cross-talk regulates lymphatic endothelial junctions in lymph nodes., PMID:31147448

LPA1 , LPA2 , LPA4 , and LPA6 receptor expression during mouse brain development., PMID:30847983

Molecular mechanism of lysophosphatidic acid-induced hypertensive response., PMID:30804442

Lipid-Lowering Agents., PMID:30702996

Moving Targets: Recent Advances in Lipid-Lowering Therapies., PMID:30676072

Lysophosphatidic acid triggers cathepsin B-mediated invasiveness of human endometriotic cells., PMID:30591146

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1486

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Research Grade Anti-LPA/Lysophosphatidic acid Antibody (504B3) [DHC33403]
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