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Anti-HSV-1/HHV-1 gE Polyclonal Antibody

Catalog #:   PVV21501 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: P04488
Overview

Catalog No.

PVV21501

Species reactivity

Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1)

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant HSV-1/HHV-1 gE (Lys24-Arg419).

Target

gE, Envelope glycoprotein E

Concentration

1.49 mg/ml

Purification

Antigen affinity purification.

Accession

P04488

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with gE/Envelope glycoprotein E antibody (PVV21501) at 1 µg/ml.

    Lane 1: Recombinant Protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 45 kDa
    Observed MW: 45 kDa
References

Herpes simplex virus 1 fusion glycoprotein B H516P prefusion mutation had no effect on vaccine immunogenicity., PMID:40354699

Phase Ib/II trial of talimogene laherparepvec alone and with pembrolizumab in advanced solid tumors with liver metastases and hepatocellular carcinoma., PMID:40156118

Analysis of the Interaction Between the Attenuated HSV-1 Strain M6 and Macrophages Indicates Its Potential as an Effective Vaccine Immunogen., PMID:40143320

Herpes simplex virus 1 envelope glycoprotein C shields glycoprotein D to protect virions from entry-blocking antibodies., PMID:40135897

Immune Response Elicited by Recombinant Adenovirus-Delivered Glycoprotein B and Nucleocapsid Protein UL18 and UL25 of HSV-1 in Mice., PMID:39769249

A replication-incompetent adenoviral vector encoding for HSV-2 gD2 is immunogenic and protective against HSV-2 intravaginal challenge in mice., PMID:39739963

Improving antibody-mediated protection against HSV infection by eliminating interactions with the viral Fc receptor gE/gI., PMID:39605495

A Herpes Simplex Virus Type-1-Derived Influenza Vaccine Induces Balanced Adaptive Immune Responses and Protects Mice From Lethal Influenza Virus Challenge., PMID:39568407

Equine Herpesvirus Type 1 ORF76 Encoding US9 as a Neurovirulence Factor in the Mouse Infection Model., PMID:39452736

Improved antitumor effectiveness of oncolytic HSV-1 viruses engineered with IL-15/IL-15Rα complex combined with oncolytic HSV-1-aPD1 targets colon cancer., PMID:39389985

High level of immunoglobulin G targeting mycoplasma or cytomegalovirus in the newborn increases risk of ADHD., PMID:39260764

Immunogenicity and protective efficacy of a recombinant lactococcus lactis vaccine against HSV-1 infection., PMID:39252072

The role of herpes simplex virus infection in the etiology of head and neck cancer-a Mendelian randomization study., PMID:39161761

Biomarkers of neural integrity and immunoglobulin genes influence neurodegeneration in Alzheimer's disease., PMID:39142084

A Broad Influenza Vaccine Based on a Heat-Activated, Tissue-Restricted Replication-Competent Herpesvirus., PMID:39066341

HSV-1 and Cellular miRNAs in CSF-Derived Exosomes as Diagnostically Relevant Biomarkers for Neuroinflammation., PMID:39056790

B Cell-activating factor (BAFF): A promising trans-nosographic biomarker of inflammation and autoimmunity in bipolar disorder and schizophrenia., PMID:39047848

High silent prevalence of human herpesvirus 1 (HSV-1) infection affecting the indigenous reservation of the municipality of Dourados, Central-West Brazil., PMID:39020287

Seroprevalence of herpes simplex virus type 1 (Herpesviridae: Simplexvirus: Human alphaherpesvirus 1) in smokers., PMID:38843024

An oncolytic HSV-1 armed with Visfatin enhances antitumor effects by remodeling tumor microenvironment against murine pancreatic cancer., PMID:38723415

HERPES SIMPLEX VIRUS-1 SUSCEPTIBILITY AS A RISK FACTOR FOR SEPSIS, WITH CYTOMEGALOVIRUS SUSCEPTIBILITY ELEVATING SEVERITY: INSIGHTS FROM A BIDIRECTIONAL MENDELIAN RANDOMIZATION STUDY., PMID:38662585

Incongruence between confirmed and suspected clinical cases of Japanese encephalitis virus infection., PMID:38343888

Mendelian randomization reveals no correlations between herpesvirus infection and idiopathic pulmonary fibrosis., PMID:38015883

Characteristics and long-term prognosis of Danish residents with a positive intrathecal antibody index test for herpes simplex virus or varicella-zoster virus compared with individuals with a positive cerebrospinal fluid PCR: a nationwide cohort study., PMID:37967615

Selection, activity, and nuclease stabilization of cross-neutralizing DNA aptamers targeting HSV-1 and HSV-2., PMID:37925791

Viral codon optimization on SARS-CoV-2 Spike boosts immunity in the development of COVID-19 mRNA vaccines., PMID:37861466

Acute Retinal Necrosis: Experience in a Reference Center in Santander - Colombia., PMID:37582226

Amino acids 1811-1960 of myosin heavy chain 9 is involved in murine gammaherpesvirus 68 infection., PMID:37515945

A Trivalent HSV-2 gC2, gD2, gE2 Nucleoside-Modified mRNA-LNP Vaccine Provides Outstanding Protection in Mice against Genital and Non-Genital HSV-1 Infection, Comparable to the Same Antigens Derived from HSV-1., PMID:37515169

Rapid detection of varicella-zoster virus based on an immunochromatographic strip., PMID:37481958

Dual impacts of a glycan shield on the envelope glycoprotein B of HSV-1: evasion from human antibodies in vivo and neurovirulence., PMID:37366623

Association between human genetic variants affecting the host NK cell response and the development of herpes simplex virus type 1 encephalitis., PMID:37212301

An evaluation of a multiplex PCR assay for the detection of Treponema pallidum, HSV-1, and HSV-2., PMID:37172529

Talimogene laherparepvec in combination with ipilimumab versus ipilimumab alone for advanced melanoma: 5-year final analysis of a multicenter, randomized, open-label, phase II trial., PMID:37142291

Seroprevalence of Herpes Simplex Viruses Types 1 and 2 in a Population, Age 15-35 Years, of Mashhad City., PMID:37070598

Cell-to-cell spread inhibiting antibodies constitute a correlate of protection against herpes simplex virus type 1 reactivations: A retrospective study., PMID:37006290

An oncolytic herpes simplex virus type 1 strain expressing a single-chain variable region antibody fragment against PD-1 and a PI3K inhibitor synergize to elicit antitumor immunity in ovarian cancer., PMID:37002434

[The incidence of infection in tumor and eye fluid system, and specific humoral immunity to herpes viruses in patients with uveal melanoma]., PMID:36961234

Mendelian randomization analysis suggests no associations of herpes simplex virus infections with systemic lupus erythematosus., PMID:36897027

Herpes Simplex Virus 1 (HSV-1) Infected Cell Protein 0 (ICP0) Targets of Ubiquitination during Productive Infection of Primary Adult Sensory Neurons., PMID:36769256

A non-neutralizing glycoprotein B monoclonal antibody protects against herpes simplex virus disease in mice., PMID:36454639

Do common infections trigger disease-onset or -severity in CTLA-4 insufficiency?, PMID:36405723

Specific targeting of glioblastoma with an oncolytic virus expressing a cetuximab-CCL5 fusion protein via innate and adaptive immunity., PMID:36357700

Tyramide Signal Amplification for the Immunofluorescent Staining of ZBP1-dependent Phosphorylation of RIPK3 and MLKL After HSV-1 Infection in Human Cells., PMID:36342164

Herpes simplex virus and rates of cognitive decline or whole brain atrophy in the Dominantly Inherited Alzheimer Network., PMID:36189728

HSV-1 0∆NLS vaccine elicits a robust B lymphocyte response and preserves vision without HSV-1 glycoprotein M or thymidine kinase recognition., PMID:36151255

Primary HSV-2 Infection Complicated by Radiculomyelitis in a Young Immunocompetent Female Patient with Inherited Chromosomally Integrated HHV-6: A Case Report., PMID:36146785

Cross protective efficacy of the Non-Neurotropic live attenuated herpes simplex virus type 1 vaccine VC-2 is enhanced by intradermal vaccination and deletion of glycoprotein G., PMID:36114130

Herpes Simplex Virus Infection Increases Beta-Amyloid Production and Induces the Development of Alzheimer's Disease., PMID:36093396

Immunoglobulin γ chain allotypes and humoral immunity to HSV1 in Parkinson's disease., PMID:35964450

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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Anti-HSV-1/HHV-1 gE Polyclonal Antibody [PVV21501]
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