Catalog No.
PHG03901
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human ICA1 (Met1-Gly258).
Target
p69, ICA1, Islet cell autoantigen 1, ICA69, 69 kDa islet cell autoantigen, ICAp69, Islet cell autoantigen p69
Purification
Antigen affinity purification.
Accession
Q05084
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Runs of Homozygosity in Modern Chicken Revealed by Sequence Data., PMID:33077478
Replication of GWAS-identified systemic lupus erythematosus susceptibility genes affirms B-cell receptor pathway signalling and strengthens the role of IRF5 in disease susceptibility in a Northern European population., PMID:22039224
The three ZNT8 autoantibody variants together improve the diagnostic sensitivity of childhood and adolescent type 1 diabetes., PMID:21244337
ICA69 autoantibodies in primary Sjögren's syndrome., PMID:15303579
Reduced thymic expression of islet antigen contributes to loss of self-tolerance., PMID:14679103
Human anti-thyroid peroxidase single-chain fragment variable of Ig isolated from a combinatorial library assembled in-cell: insights into the in vivo situation., PMID:10754281
Autoreactive T cell responses in insulin-dependent (Type 1) diabetes mellitus. Report of the first international workshop for standardization of T cell assays., PMID:10479395
Production of the islet cell antigen ICA69 (p69) with baculovirus expression system: analysis with a solid-phase time-resolved fluorescence method of sera from patients with IDDM and rheumatoid arthritis., PMID:10433084
Anti-BSA antibodies do not cross-react with the 69-kDa islet cell autoantigen ICA69., PMID:9693970
Th1-like cytokine production profile and individual specific alterations in TCRBV-gene usage of T cells from newly diagnosed type 1 diabetes patients after stimulation with beta-cell antigens., PMID:9451599
Islet cell autoantigen 69 kDa (ICA69) is preferentially expressed in the human islets of Langerhans than exocrine pancreas., PMID:9028728
Antigenic determinants in type 1 diabetes mellitus. Review article., PMID:8982239
Islet cell autoantigen 69 antibodies in IDDM., PMID:8781774
HLA-associated inverse correlation between T cell and antibody responsiveness to islet autoantigen in recent-onset insulin-dependent diabetes mellitus., PMID:8647206
Gene expression of islet cell antigen p69 in human, mouse, and rat., PMID:8603775
Glutamic acid decarboxylase and other autoantigens in IDDM., PMID:8679127
Islet cell and thyroid autoimmunity in Chinese patients with IDDM., PMID:7497880
Autoantibodies to the islet antigen ICA69 occur in IDDM and in rheumatoid arthritis., PMID:7758883
Cloning of human and rat p69 cDNA, a candidate autoimmune target in type 1 diabetes., PMID:7918678
Sera from patients with IDDM and healthy individuals have antibodies to ICA69 on western blots but do not immunoprecipitate liquid phase antigen., PMID:7840858
Prediction and prevention of type I diabetes., PMID:8171463
Islet cell autoantigen 69 kD (ICA69). Molecular cloning and characterization of a novel diabetes-associated autoantigen., PMID:8326004
Pancreatic antigenic complex p64 69: involvement in regulation of insulin secretion and relation to glutamic acid decarboxylase., PMID:1548042
Modelling of type 1 diabetes with monoclonal antibody ICA-1., PMID:2102778
Immunoreactivity of cultured pancreatic islet cells with monoclonal antibody ICA-1., PMID:2130918
Pancreatic islet cells in tissue culture: function and immunoreactivity with serum autoantibodies from diabetes type-1 patients and monoclonal antibodies ICA-1., PMID:2673809
Clinical studies on ionized calcium using the radiometer ICA1 analyzer., PMID:6578583
For research use only. Not for human or drug use.
