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Recombinant Human PENK Protein, N-His

Catalog #:   YHB92301 Specific References (50) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: P01210
Protein length: Glu25-Ala133
Overview

Catalog No.

YHB92301

Expression system

E. coli

Species

Homo sapiens (Human)

Protein length

Glu25-Ala133

Predicted molecular weight

14.69 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

P01210

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

Opioid growth factor, OGF, PENK, Proenkephalin-A

Data Image
  • SDS-PAGE
    SDS PAGE for recombinant Human PENK protein
References

The Identification of Opioid Receptors and Peptide Precursors in Human DRG Neurons Expressing Pain-Signaling Molecules Confirms Their Potential as Analgesic Targets., PMID:40422197

Novel biomarkers for predicting successful liberation of renal replacement therapy for acute kidney injury: a systematic review., PMID:40420198

Markers of Kidney Injury: Proenkephalin A and Uromodulin, but Not Dickkopf-3, Are Elevated in Patients After Hematopoietic Stem Cell Transplantation., PMID:40332103

Implementation and One-Year Evaluation of Proenkephalin A in Critical Care., PMID:40141244

GALR1 and PENK serve as potential biomarkers in invasive non-functional pituitary neuroendocrine tumours., PMID:40024300

Computational Engineering of siderocalin to modulate its binding affinity to the antihypertension drug candesartan., PMID:39978741

Urinary DNA Methylation Test for Bladder Cancer Diagnosis., PMID:39883469

Somatic CAG repeat expansion in blood associates with biomarkers of neurodegeneration in Huntington's disease decades before clinical motor diagnosis., PMID:39825149

Estrogen-Regulated Lateral Septal Kisspeptin Neurons Abundantly Project to GnRH Neurons and the Hypothalamic Supramammillary Nucleus., PMID:39746822

Prenatal exposure to valproic acid induces sex-specific alterations in rat cortical and hippocampal neuronal structure and function in vitro., PMID:39701172

High-gamma frequency flash stimulation as a possible cognitive facilitator in rat pups., PMID:39549826

Identification of immune feature genes and intercellular profiles in diabetic cardiomyopathy., PMID:39493556

Prediction of Successful Liberation from Continuous Renal Replacement Therapy Using a Novel Biomarker in Patients with Acute Kidney Injury after Cardiac Surgery-An Observational Trial., PMID:39456654

Deciphering Peripheral Taste Neuron Diversity: Using Genetic Identity to Bridge Taste Bud Innervation Patterns and Functional Responses., PMID:39379155

A comparison of the renal function biomarkers serum creatinine, pro-enkephalin and cystatin C to predict clearance of pemetrexed., PMID:39365467

Proenkephalin improves cardio-renal risk prediction in acute coronary syndromes: the KID-ACS score., PMID:39215600

Analgesic targets identified in mouse sensory neuron somata and terminal pain translatomes., PMID:39163201

Central δ/κ opioid receptor signaling pathways mediate chronic and/or acute suckling-induced LH suppression in rats during late lactation., PMID:39155080

Rational design of glycosaminoglycan binding cyclic peptides using cPEPmatch., PMID:39135886

Persistent acute kidney injury biomarkers: A systematic review and meta-analysis., PMID:39127297

Distinct basal forebrain-originated neural circuits promote homoeostatic feeding and suppress hedonic feeding in male mice., PMID:39112722

Enkephalin-mediated modulation of basal somatic sensitivity by regulatory T cells in mice., PMID:39110619

Evaluation of Kynu, Defb2, Camp, and Penk Expression Levels as Psoriasis Marker in the Imiquimod-Induced Psoriasis Model., PMID:39045230

Identification of new targets for glioblastoma therapy based on a DNA expression microarray., PMID:38981212

Plasma proenkephalin and neutrophil gelatinase-associated lipocalin predict mortality in ICU patients with acute kidney injury., PMID:38778257

Furosemide stress test to predict acute kidney injury progression in critically ill children., PMID:38691152

Research Note: Morphine influences circulating and tissue concentrations of met-enkephalin and proenkephalin (PENK) expression and plasma concentrations of corticosterone in chickens., PMID:38603935

Prognostic Biomarkers and AKI: Potential to Enhance the Identification of Post-Operative Patients at Risk of Loss of Renal Function., PMID:38476861

Spatial transcriptomics reveal neuron-astrocyte synergy in long-term memory., PMID:38326616

A novel investigation into the negative impact of opioid use on the efficacy of immune checkpoint inhibitors in advanced non-small cell lung cancer patients., PMID:38325047

Deciphering Immune-related Gene Signatures in Diabetic Retinopathy: Insights from In silico Analysis and In vitro Experiment., PMID:38310446

Plasma proenkephalin A and incident chronic kidney disease and albuminuria in the REasons for Geographic And Racial Differences in Stroke (REGARDS) cohort., PMID:38200454

Detecting Protein-Ligand Interactions with Nitroxide Based Paramagnetic Cosolutes., PMID:38018494

Dimerization and Crowding in the Binding of Interleukin 8 to Dendritic Glycosaminoglycans as Artificial Proteoglycans., PMID:38010268

Tonantzitlolone B Modulates the Endogenous Opioid System to Promote Antinociception in Mice., PMID:37948340

Transcriptional profiling of Kiss1 neurons from arcuate and rostral periventricular hypothalamic regions in female mice., PMID:37934722

Nuclear magnetic resonance spectroscopy to quantify major extracellular matrix components in fibro-calcific aortic valve disease., PMID:37914797

Placental mesenchymal stem cells-secreted proenkephalin suppresses the p38 MAPK signaling to block hyperproliferation of keloid fibroblasts., PMID:37913601

Lateral hypothalamic proenkephalin neurons drive threat-induced overeating associated with a negative emotional state., PMID:37898655

Use of lactulose as a prebiotic in laying hens: its effect on growth, egg production, egg quality, blood biochemistry, digestive enzymes, gene expression and intestinal morphology., PMID:37845670

Ligand binding of interleukin-8: a comparison of glycosaminoglycans and acidic peptides., PMID:37694394

A body composition model with multiple storage compartments for polar bears (Ursus maritimus)., PMID:37346266

Enkephalin-δ opioid receptor signaling partly mediates suppression of LH release during early lactation in rats., PMID:37331801

Bioinformatics Analysis of Differentially Expressed Genes in Ischemic Cardiomyopathy Using GEO Database., PMID:37213148

Urinary Proteins of Female Domestic Dog (Canis familiaris) during Ovarian Cycle., PMID:37104448

Up-regulation of BDNF/TrkB signaling by δ opioid receptor agonist SNC80 modulates depressive-like behaviors in chronic restraint-stressed mice., PMID:36708979

Identification and validation of oxidative stress and immune-related hub genes in Alzheimer's disease through bioinformatics analysis., PMID:36635346

Enkephalin-δ Opioid Receptor Signaling Mediates Glucoprivic Suppression of LH Pulse and Gluconeogenesis in Female Rats., PMID:36592113

NaV1.7 Channel Blocker [Ala5, Phe6, Leu26, Arg28]GpTx-1 Attenuates CFA-induced Inflammatory Hypersensitivity in Rats via Endogenous Enkephalin Mechanism., PMID:36586660

Cerebrospinal fluid biomarkers for assessing Huntington disease onset and severity., PMID:36523269

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

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For research use only. Not for human or drug use.

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Recombinant Human PENK Protein, N-His [YHB92301]
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