Catalog No.
FHN03712
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Conjugation
PE
Applications
ELISA, FCM
Target
Magic roundabout, ROBO4, Roundabout homolog 4
Concentration
0.5 mg/ml
Endotoxin level
Please contact with the lab for this information.
Accession
Q8WZ75
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.
Stability and Storage
Store at 4°C for 12 months. Protect from light. Do not freeze.
Clone ID
MAb1
Note
For research use only.
Soluble Robo4 receptor inhibits in vivo angiogenesis and endothelial cell migration., PMID:15486058
Serum levels of Magic Roundabout protein in patients with advanced non-small cell lung cancer (NSCLC)., PMID:15949592
A three-kilobase fragment of the human Robo4 promoter directs cell type-specific expression in endothelium., PMID:17495228
New targeted probes for radioimaging of angiogenesis., PMID:19318127
Radionuclide imaging of tumor angiogenesis., PMID:20025543
Robo4 maintains vessel integrity and inhibits angiogenesis by interacting with UNC5B., PMID:21238923
The axonal repellent Slit2 inhibits pericyte migration: potential implications in angiogenesis., PMID:22198087
Robo4 is an effective tumor endothelial marker for antibody-drug conjugates based on the rapid isolation of the anti-Robo4 cell-internalizing antibody., PMID:23365463
New antiangiogenic strategies beyond inhibition of vascular endothelial growth factor with special focus on axon guidance molecules., PMID:24401553
Robo4 vaccines induce antibodies that retard tumor growth., PMID:25348086
Overexpression of Roundabout4 predicts poor prognosis of primary glioma patients via correlating with microvessel density., PMID:25859844
Investigation of the Regulation of Roundabout4 by Hypoxia-Inducible Factor-1α in Microvascular Endothelial Cells., PMID:26066603
Expression of Robo protein in bladder cancer tissues and its effect on the growth of cancer cells by blocking Robo protein., PMID:26617702
Suppression of Slit2/Robo1 mediated HUVEC migration by Robo4., PMID:26713366
Review: The transcripts associated with organ allograft rejection., PMID:29178397
Plasma Biomarkers of Inflammation and Angiogenesis Predict Cerebral Cavernous Malformation Symptomatic Hemorrhage or Lesional Growth., PMID:29720384
Slit2/Robo4 axis may contribute to endothelial cell dysfunction and angiogenesis disturbance in systemic sclerosis., PMID:30021803
Robo4 contributes to the turnover of Peyer's patch B cells., PMID:31772321
DS-7080a, a Selective Anti-ROBO4 Antibody, Shows Anti-Angiogenic Efficacy with Distinctly Different Profiles from Anti-VEGF Agents., PMID:32879763
Mechanism of TLR4 mediated immune effect in transfusion-induced acute lung injury based on Slit2/Robo4 signaling pathway., PMID:35853810
Relationship between blood and tissue-based rejection-related transcripts in heart transplantation., PMID:37730189
Relationship between donor-derived cell-free DNA and tissue-based rejection-related transcripts in heart transplantation., PMID:38373559
Potential Therapeutic Strategies and Drugs That Target Vascular Permeability in Severe Infectious Diseases., PMID:38432910
For research use only. Not for human or drug use.
