Catalog No.
FHG33712
Species reactivity
Human
Host species
Mouse
Isotype
IgG1, kappa
Clonality
Monoclonal
Conjugation
PE
Target
HPTP eta, R-PTP-J, Protein-tyrosine phosphatase eta, Density-enhanced phosphatase 1, Receptor-type tyrosine-protein phosphatase eta, Protein-tyrosine phosphatase receptor type J, DEP-1, R-PTP-eta, CD148, PTPRJ, DEP1
Concentration
0.5 mg/ml
Endotoxin level
Please contact with the lab for this information.
Accession
Q12913
Applications
FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.
Stability and Storage
Store at 4°C for 12 months. Protect from light. Do not freeze.
Clone ID
AB-2
Note
For research use only.
Activation of the interleukin 2 pathway precedes CD3-T cell receptor expression in thymic development. Differential growth requirements of early and mature intrathymic subpopulations., PMID:2522051
Molecular cloning, characterization, and chromosomal localization of a novel protein-tyrosine phosphatase, HPTP eta., PMID:7994032
Functional characterization of receptor-type protein tyrosine phosphatase CD148 (HPTP eta/DEP-1) in Fc gamma receptor IIa signal transduction of human neutrophils., PMID:9464844
CD148 is a membrane protein tyrosine phosphatase present in all hematopoietic lineages and is involved in signal transduction on lymphocytes., PMID:9531590
CD148: a receptor-type protein tyrosine phosphatase involved in the regulation of human T cell activation., PMID:9759839
From sentinel to messenger: an extended phenotypic analysis of the monocyte to dendritic cell transition., PMID:9767444
Identification of functional human splenic memory B cells by expression of CD148 and CD27., PMID:9802981
Novel molecular mechanisms of dendritic cell-induced T cell activation., PMID:10882417
Autoantibodies to inner ear and endothelial antigens in Cogan's syndrome., PMID:12354474
Antigenic profile of human thymus in concurrence with "Clusters of Thymic Epithelial Staining" classification., PMID:12725440
The tyrosine phosphatase CD148 is excluded from the immunologic synapse and down-regulates prolonged T cell signaling., PMID:12913111
Sensori-neural deafness and hypothyroidism: autoimmunity causing 'pseudo-Pendred syndrome'., PMID:16582570
A monoclonal antibody against CD148, a receptor-like tyrosine phosphatase, inhibits endothelial-cell growth and angiogenesis., PMID:16597593
Structurally distinct phosphatases CD45 and CD148 both regulate B cell and macrophage immunoreceptor signaling., PMID:18249142
CD148/DEP-1 association with areas of cytoskeletal organisation in macrophages., PMID:19268662
Proteomic analysis of malignant B-cell derived microparticles reveals CD148 as a potentially useful antigenic biomarker for mantle cell lymphoma diagnosis., PMID:19413345
Stable isotope labeling by amino acids in cell culture and differential plasma membrane proteome quantitation identify new substrates for the MARCH9 transmembrane E3 ligase., PMID:19457934
Analysis of HLDA9 mAbs on plasmacytoid dendritic cells., PMID:20933012
Retinal angiomatosis and cystoid macular oedema in Cogan's syndrome., PMID:21873927
Quantitative differences in CD45 expression unmask functions for CD45 in B-cell development, tolerance, and survival., PMID:22135465
Protein tyrosine phosphatases in lymphocyte activation and autoimmunity., PMID:22513334
Polymorphisms of protein tyrosine phosphatase CD148 influence FcγRIIA-dependent platelet activation and the risk of heparin-induced thrombocytopenia., PMID:22677127
Tyrosine phosphorylation of DEP-1/CD148 as a mechanism controlling Src kinase activation, endothelial cell permeability, invasion, and capillary formation., PMID:22898603
Dominant role of the protein-tyrosine phosphatase CD148 in regulating platelet activation relative to protein-tyrosine phosphatase-1B., PMID:23065825
Association of the protein-tyrosine phosphatase DEP-1 with its substrate FLT3 visualized by in situ proximity ligation assay., PMID:23650535
Identification of autoantibodies against inner ear antigens in a cohort of children with idiopathic sensorineural hearing loss., PMID:23944678
Cell surface phenotype profiles distinguish stable and progressive chronic lymphocytic leukemia., PMID:24289109
Cogan's syndrome--clinical guidelines and novel therapeutic approaches., PMID:24385257
The mycotoxin patulin decreases expression of density-enhanced phosphatase-1 by down-regulating PPARγ in human colon cancer cells., PMID:25098256
Risk factors for heparin-induced thrombocytopenia: Focus on Fcγ receptors., PMID:27358188
Positive Regulation of Lyn Kinase by CD148 Is Required for B Cell Receptor Signaling in B1 but Not B2 B Cells., PMID:27889108
Targeting Receptor-Type Protein Tyrosine Phosphatases with Biotherapeutics: Is Outside-in Better than Inside-Out?, PMID:29498714
Agonistic anti-CD148 monoclonal antibody attenuates diabetic nephropathy in mice., PMID:31984788
A high-resolution mass spectrometry based proteomic dataset of human regulatory T cells., PMID:34950757
Syndecan-2 regulates PAD2 to exert antifibrotic effects on RA-ILD fibroblasts., PMID:35181688
A phosphatase-recruiting bispecific antibody-aptamer chimera for enhanced suppression of tumor growth., PMID:37170857
CD148 agonistic antibody alleviates renal injury induced by chronic angiotensin II infusion in mice., PMID:40165104
Relieving platelet inhibition using a novel bi-specific antibody: A novel approach for circumventing the platelet storage lesion., PMID:40166144
For research use only. Not for human or drug use.
