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Anti-Human CD96 Antibody (BA072), PE

Catalog #:   FHE25712 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1, kappa
Applications: FCM
Accession: P40200
Overview

Catalog No.

FHE25712

Species reactivity

Human

Host species

Mouse

Isotype

IgG1, kappa

Clonality

Monoclonal

Conjugation

PE

Target

Cell surface antigen CD96, T cell-activated increased late expression protein, CD96, T-cell surface protein tactile

Concentration

0.5 mg/ml

Endotoxin level

Please contact with the lab for this information.

Accession

P40200

Applications

FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Stability and Storage

Store at 4°C for 12 months. Protect from light. Do not freeze.

Clone ID

BA072

Note

For research use only.

Data Image
References

Monoclonal antibody therapy directed against human acute myeloid leukemia stem cells., PMID:21076471

Identification of endothelial cell junctional proteins and lymphocyte receptors involved in transendothelial migration of human effector memory CD4+ T cells., PMID:21191062

[Human CD96 gene cloning, expression and identification]., PMID:21764703

Enhanced ADCC activity of affinity maturated and Fc-engineered mini-antibodies directed against the AML stem cell antigen CD96., PMID:22879978

Strategies for purging CD96+ stem cells in vitro and in vivo: New avenues for autologous stem cell transplantation in acute myeloid leukemia., PMID:23894710

[Expression, crystallization and crystallographic study of the 1st IgV domain of human CD96]., PMID:24010363

T-cell Ig and ITIM domain regulates natural killer cell activation in murine acute viral hepatitis., PMID:24319005

Suppression of Metastases Using a New Lymphocyte Checkpoint Target for Cancer Immunotherapy., PMID:26787820

Molecular Pathways: Targeting CD96 and TIGIT for Cancer Immunotherapy., PMID:27620276

Antibody-dependent cell cytotoxicity: immunotherapy strategies enhancing effector NK cells., PMID:28138156

TIGIT and CD96: new checkpoint receptor targets for cancer immunotherapy., PMID:28258695

CD137 (4-1BB) Costimulation Modifies DNA Methylation in CD8+ T Cell-Relevant Genes., PMID:29133290

CD96 targeted antibodies need not block CD96-CD155 interactions to promote NK cell anti-metastatic activity., PMID:29721390

Coming of Age: CD96 Emerges as Modulator of Immune Responses., PMID:29868026

Targeting Checkpoint Receptors and Molecules for Therapeutic Modulation of Natural Killer Cells., PMID:30250471

Genetic association between CD96 locus and immunogenicity to anti-TNF therapy in Crohn's disease., PMID:31043678

NK Cell Dysfunction and Checkpoint Immunotherapy., PMID:31552017

CD96 functions as a co-stimulatory receptor to enhance CD8+ T cell activation and effector responses., PMID:32043568

Targeting the "PVR-TIGIT axis" with immune checkpoint therapies., PMID:32489646

[Inhibition of CD96 enhances interferon-γ secretion by natural killer cells to alleviate lung injury in mice with pulmonary Chlamydia muridarum infection]., PMID:32895152

Delineation of target expression profiles in CD34+/CD38- and CD34+/CD38+ stem and progenitor cells in AML and CML., PMID:33085758

Expression of putative leukemia stem cell targets in genetically-defined acute myeloid leukemia subtypes., PMID:33220589

An obstructive role of NK cells on metastatic growth of clear-cell sarcoma cells in a xenoplant murine model., PMID:33262889

Hitting the complexity of the TIGIT-CD96-CD112R-CD226 axis for next-generation cancer immunotherapy., PMID:33298247

T-cell immunoglobulin and ITIM domain, as a potential immune checkpoint target for immunotherapy of colorectal cancer., PMID:33686787

Therapeutic Targeting of Checkpoint Receptors within the DNAM1 Axis., PMID:33687987

Asynchronous blockade of PD-L1 and CD155 by polymeric nanoparticles inhibits triple-negative breast cancer progression and metastasis., PMID:34186238

Differential impacts of TNFα inhibitors on the transcriptome of Th cells., PMID:34301319

Inhibitory Receptors and Immune Checkpoints Regulating Natural Killer Cell Responses to Cancer., PMID:34503073

Antibody blockade of CD96 by distinct molecular mechanisms., PMID:34595996

Crohn's Disease and Early Exposure to Thiopurines are Independent Risk Factors for Mosaic Chromosomal Alterations in Patients with Inflammatory Bowel Diseases., PMID:34751398

Targeting PD-L1 and TIGIT could restore intratumoral CD8 T cell function in human colorectal cancer., PMID:35292828

Emergence of the CD226 Axis in Cancer Immunotherapy., PMID:35812451

Abnormal expression of CD96 on natural killer cell in peripheral blood of patients with chronic obstructive pulmonary disease., PMID:35866671

Fcγ receptor-mediated cross-linking codefines the immunostimulatory activity of anti-human CD96 antibodies., PMID:35998045

Natural killer cell profiles in recurrent pregnancy loss: Increased expression and positive associations with TACTILE and LILRB1., PMID:36004818

Evaluating Antibody Pharmacokinetics as Prerequisite for Determining True Efficacy as Shown by Dual Targeting of PD-1 and CD96., PMID:36140247

Advances in therapeutic targeting of immune checkpoints receptors within the CD96-TIGIT axis: clinical implications and future perspectives., PMID:36154551

An Inhibitory Role for Human CD96 Endodomain in T Cell Anti-Tumor Responses., PMID:36672244

The IgV domain of the poliovirus receptor alone is immunosuppressive and binds to its receptors with comparable affinity., PMID:36944702

Deficiency of the CD155-CD96 immune checkpoint controls IL-9 production in giant cell arteritis., PMID:37075705

Twenty-four-color full spectrum flow cytometry panel for minimal residual disease detection in acute myeloid leukemia., PMID:37533738

Biophysical characterization of PVR family interactions and therapeutic antibody recognition to TIGIT., PMID:37675979

Poliovirus receptor inhibition in breast cancer cells induces antitumor immunity via T cell activation., PMID:38187056

Natural killer cell subsets and their functional molecules in peripheral blood of the patients with breast cancer., PMID:38652012

Platelet-mediated circulating tumor cell evasion from natural killer cell killing through immune checkpoint CD155-TIGIT., PMID:38779918

The Immune Checkpoint BTLA in Oral Cancer: Expression Analysis and Its Correlation to Other Immune Modulators., PMID:38928307

Therapeutic drug monitoring and immunogenetic factors associated with the use of adalimumab in Crohn's disease patients., PMID:39959979

Deep immunophenotyping reveals circulating activated lymphocytes in individuals at risk for rheumatoid arthritis., PMID:40091833

Predictors of Immunogenicity and Loss of Response to ANTI-TNFα Therapy in Crohn Disease-A Systematic Review., PMID:40338684

Datasheet
$ 292
Product specifications
50 T 292 100 T 484

Contact Information

Order: order@antibodysystem.com

Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

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Anti-Human CD96 Antibody (BA072), PE [FHE25712]
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