Catalog No.
FHE14012
Species reactivity
Human
Host species
Human
Isotype
IgG1, kappa
Clonality
Monoclonal
Conjugation
PE
Target
Hepatoma-associated antigen, BSG, HAb18G, 5F7, TCSF, OK blood group antigen, Collagenase stimulatory factor, CD147, Leukocyte activation antigen M6, Basigin, Extracellular matrix metalloproteinase inducer, EMMPRIN, Tumor cell-derived collagenase stimulatory factor
Concentration
0.5 mg/ml
Endotoxin level
Please contact with the lab for this information.
Accession
P35613
Applications
FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.
Stability and Storage
Store at 4°C for 12 months. Protect from light. Do not freeze.
Clone ID
SAA0061
Note
For research use only.
Extracellular Vesicles Isolated from Plasma of Multiple Myeloma Patients Treated with Daratumumab Express CD38, PD-L1, and the Complement Inhibitory Proteins CD55 and CD59., PMID:36359760
Novel Antibody Exerts Antitumor Effect through Downregulation of CD147 and Activation of Multiple Stress Signals., PMID:36385956
ACE2-Independent Alternative Receptors for SARS-CoV-2., PMID:36423144
CD147 contributes to SARS-CoV-2-induced pulmonary fibrosis., PMID:36424379
SARS-CoV-2 Spike Protein Induces Hemagglutination: Implications for COVID-19 Morbidities and Therapeutics and for Vaccine Adverse Effects., PMID:36555121
Safety, Biodistribution, and Dosimetry Study of Meplazumab, a Potential COVID-19 Therapeutic Drug, with 131I-Labeling and SPECT Imaging., PMID:36668905
Immunological and metabolic characteristics of the Omicron variants infection., PMID:36681668
Meplazumab in hospitalized adults with severe COVID-19 (DEFLECT): a multicenter, seamless phase 2/3, randomized, third-party double-blind clinical trial., PMID:36717539
Spike Protein Impairs Mitochondrial Function in Human Cardiomyocytes: Mechanisms Underlying Cardiac Injury in COVID-19., PMID:36980218
Repurposing niclosamide as a novel anti-SARS-Cov-2 drug by restricting entry protein CD147., PMID:37090542
Diabetes, COVID-19, and questions unsolved., PMID:37209039
Differential Effects of Anti-PD-1/PD-L1 Checkpoint Inhibitors on Adhesion Molecules and Cytokine Secretion by THP-1 Monocytes., PMID:37247886
Combination Therapy With CD147-Targeted Nanoparticles Carrying Phenformin Decreases Lung Cancer Growth., PMID:37303292
Dextran-doxorubicin prodrug nanoparticles conjugated with CD147 monoclonal antibody for targeted drug delivery in hepatoma therapy., PMID:37331192
CD147 monoclonal antibody attenuates abdominal aortic aneurysm formation in angiotensin II-Infused apoE-/- mice., PMID:37393837
Repurposing Niclosamide as a Novel Anti-SARS-CoV-2 Drug by Restricting Entry Protein CD147., PMID:37509657
Identification of CD147-positive extracellular vesicles as novel non-invasive biomarkers for the diagnosis and prognosis of colorectal cancer., PMID:37562522
Comprehensive cell surface protein profiling of human mesenchymal stromal cells from peritoneal dialysis effluent and comparison with those from human bone marrow and adipose tissue., PMID:37603218
SETDB1-mediated CD147-K71 di-methylation promotes cell apoptosis in non-small cell lung cancer., PMID:37692516
124I-labeled anti-CD147 antibody for noninvasive detection of CD147-positive pan-cancers: construction and preclinical studies., PMID:37749238
Multiplex Quantification of Exosomes via Multiple Types of Nanobeads Labeling Combined with Laser Scanning Detection., PMID:37812687
CD147: an integral and potential molecule to abrogate hallmarks of cancer., PMID:38023152
Novel Pharmacological Treatment Options of Steroid-Refractory Graft-versus-Host Disease., PMID:38094101
CD147 Sparks Atherosclerosis by Driving M1 Phenotype and Impairing Efferocytosis., PMID:38166463
CD147 induces asthmatic airway remodeling and activation of circulating fibrocytes in a mouse model of asthma., PMID:38178133
Soluble CD147 regulates endostatin via its effects on the activities of MMP-9 and secreted proteasome 20S., PMID:38318187
Hypoxia-activated ADCC-enhanced humanized anti-CD147 antibody for liver cancer imaging and targeted therapy with improved selectivity., PMID:38469549
The use of human iPSC-derived alveolar organoids to explore SARS-CoV-2 variant infections and host responses., PMID:38572923
Comparative assessment of different anti-CD147/Basigin 2 antibodies as a potential therapeutic anticancer target by molecular modeling and dynamic simulation., PMID:38587771
Preconditioning-Induced Facilitation of Lactate Release from Astrocytes Is Essential for Brain Ischemic Tolerance., PMID:38604775
Glucose Promotes EMMPRIN/CD147 and the Secretion of Pro-Angiogenic Factors in a Co-Culture System of Endothelial Cells and Monocytes., PMID:38672062
Engineering Dimeric EGFR-directed IgA Antibodies Reveals a Central Role of CD147 during Neutrophil-mediated Tumor Cell Killing of Head and Neck Squamous Cancer Cells., PMID:38787053
Metal-organic framework-interfaced ELISA probe enables ultrasensitive detection of extracellular vesicle biomarkers., PMID:38856318
CD147-K148me2-Driven Tumor Cell-Macrophage Crosstalk Provokes NSCLC Immunosuppression via the CCL5/CCR5 Axis., PMID:38873823
CD147 regulates the formation and function of immune synapses., PMID:38909549
Engineered CD147-Deficient THP-1 Impairs Monocytic Myeloid-Derived Suppressor Cell Differentiation but Maintains Antibody-Dependent Cellular Phagocytosis Function for Jurkat T-ALL Cells with Humanized Anti-CD147 Antibody., PMID:38928332
Tofacitinib Regulates Endostatin via Effects on CD147 and Cathepsin S., PMID:39000375
Quantitative Membrane Proteomics for Discovery of Actionable Drug Targets at the Surface of RAS-Driven Human Cancer Cells., PMID:39052212
The binding of extracellular cyclophilin A to ACE2 and CD147 triggers psoriasis-like inflammation., PMID:39096717
Engineering affinity of humanized ScFv targeting CD147 antibody: A combined approach of mCSM-AB2 and molecular dynamics simulations., PMID:39405982
Radioiodinated Nanobody immunoPET probe for in vivo detection of CD147 in pan-cancer., PMID:39549046
Detecting monogenic disorders in utero non-invasively based on fetal nucleated red blood cells highly-purified by multi-functional magnetic nanoparticles., PMID:39947792
Cyclophilin-CD147 interaction enables SARS-CoV-2 infection of human monocytes and their activation via Toll-like receptors 7 and 8., PMID:39963132
An Anti-CD147 Antibody-Drug Conjugate Mehozumab-DM1 is Efficacious Against Hepatocellular Carcinoma in Cynomolgus Monkey., PMID:39985225
Urinary Basigin/CD147 is a useful marker of acute T cell-mediated rejection in kidney transplant recipients., PMID:40125925
EMMPRIN Correlated with β-CATENIN in Various t Stages of Colorectal Adenocarcinoma., PMID:40156418
Meplazumab, a CD147 antibody, for severe COVID-19: a double-blind, randomized, placebo-controlled, phase 3 clinical trial., PMID:40222976
Potentiating Antibody-Dependent Cellular Cytotoxicity in Triple-Negative Breast Cancer via the Humanized Anti-CD147 Antibody., PMID:40265417
Serum EMMPRIN/CD147 promotes the lung pre-metastatic niche in a D2A1 mammary carcinoma mouse model., PMID:40370456
Multimodal nanoparticles co-delivering bevacizumab and dichloroacetate for dual targeting of neoangiogenesis and hyperglycolysis in glioblastoma treatment., PMID:40482922
For research use only. Not for human or drug use.
