Catalog No.
FHD98212
Species reactivity
Human
Host species
Mouse
Isotype
IgG1, kappa
Clonality
Monoclonal
Conjugation
PE
Target
CAML1, Neural cell adhesion molecule L1, NCAM-L1, N-CAM-L1, CD171, MIC5, L1CAM
Concentration
0.5 mg/ml
Endotoxin level
Please contact with the lab for this information.
Accession
P32004
Applications
FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.
Stability and Storage
Store at 4°C for 12 months. Protect from light. Do not freeze.
Clone ID
OV52.24
Note
For research use only.
L1 adhesion molecule (CD 171) in development and progression of human malignant melanoma., PMID:12490317
Reactivity of new adhesion molecules on lymphocytes from patients with chronic graft versus host disease., PMID:12793201
Adhesion molecules CD171 (L1CAM) and CD24 are expressed by primary neuroendocrine carcinomas of the skin (Merkel cell carcinomas)., PMID:12834484
The adhesion molecule L1 (CD171) promotes melanoma progression., PMID:16506207
Absence of L1 in pancreatic masses distinguishes adenocarcinomas from poorly differentiated neuroendocrine carcinomas., PMID:16619519
Expression profile analysis in multiple human tumors identifies L1 (CD171) as a molecular marker for differential diagnosis and targeted therapy., PMID:16867862
Adoptive transfer of chimeric antigen receptor re-directed cytolytic T lymphocyte clones in patients with neuroblastoma., PMID:17299405
The L1 cell adhesion molecule is a potential biomarker of human distal nephron injury in acute tubular necrosis., PMID:18059459
Subset of esophageal adenocarcinoma expresses adhesion molecule l1 in contrast to squamous cell carcinoma., PMID:19414364
Stimulation of glioma cell motility by expression, proteolysis, and release of the L1 neural cell recognition molecule., PMID:19874583
Therapeutic antibodies to human L1CAM: functional characterization and application in a mouse model for ovarian carcinoma., PMID:20215505
DOG1 and CD117 are the antibodies of choice in the diagnosis of gastrointestinal stromal tumours., PMID:20716168
L1 is highly expressed in tumors of the nervous system: a study of over 8000 human tissues., PMID:21195422
L1CAM regulates DNA damage checkpoint response of glioblastoma stem cells through NBS1., PMID:21297581
L1 stimulation of human glioma cell motility correlates with FAK activation., PMID:21373966
Combined treatment of L1CAM antibodies and cytostatic drugs improve the therapeutic response of pancreatic and ovarian carcinoma., PMID:22210381
Diverse solid tumors expressing a restricted epitope of L1-CAM can be targeted by chimeric antigen receptor redirected T lymphocytes., PMID:24509172
Microarray profiling of L1-overexpressing endothelial cells reveals STAT3 activation via IL-6/IL-6Rα axis., PMID:26484199
Exosomal Proteins as Diagnostic Biomarkers in Lung Cancer., PMID:27343445
Preclinical Assessment of CD171-Directed CAR T-cell Adoptive Therapy for Childhood Neuroblastoma: CE7 Epitope Target Safety and Product Manufacturing Feasibility., PMID:27390347
Expression of neural cell adhesion molecule L1 (CD171) in neuroectodermal and other tumors: An immunohistochemical study of 5155 tumors and critical evaluation of CD171 prognostic value in gastrointestinal stromal tumors., PMID:27419370
Antagonistic L1 Adhesion Molecule Mimetic Compounds Inhibit Glioblastoma Cell Migration In Vitro., PMID:35327631
β-Amyloid in blood neuronal-derived extracellular vesicles is elevated in cognitively normal adults at risk of Alzheimer's disease and predicts cerebral amyloidosis., PMID:35550625
Abnormal levels of mitochondrial Ca2+ channel proteins in plasma neuron-derived extracellular vesicles of early schizophrenia., PMID:35867070
Monitoring of Post-Brain Injuries By Measuring Plasma Levels of Neuron-Derived Extracellular Vesicles., PMID:36324609
Magnetic Separation of Cell-Secreted Vesicles with Tailored Magnetic Particles and Downstream Applications., PMID:37140802
Exploring the role of neuronal-enriched extracellular vesicle miR-93 and interoception in major depressive disorder., PMID:37398092
Identification of potential molecular targets for the treatment of cluster 1 human pheochromocytoma and paraganglioma via comprehensive proteomic characterization., PMID:37749499
Exploring the role of neuronal-enriched extracellular vesicle miR-93 and interoception in major depressive disorder., PMID:38678012
For research use only. Not for human or drug use.
