Catalog No.
FHB91512
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Conjugation
PE
Target
ETGF, Protransforming growth factor alpha, TGF type 1, TGFA, EGF-like TGF, TGF-alpha
Concentration
0.5 mg/ml
Endotoxin level
Please contact with the lab for this information.
Accession
P01135
Applications
ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.
Stability and Storage
Store at 4°C for 12 months. Protect from light. Do not freeze.
Clone ID
SAA0442
Note
For research use only.
p53 overexpression correlates with increased survival in patients with squamous carcinoma of the tongue base., PMID:1463117
Differential expression of transforming growth factor alpha, adhesions molecules and integrins in primary, metastatic liver tumors and in liver cirrhosis., PMID:7539239
Epidermal growth factor receptor (EGFR) in oral squamous cell carcinomas: overexpression, localization and therapeutic implications., PMID:9495132
EGFR blockade by tyrosine kinase inhibitor or monoclonal antibody inhibits growth, directs terminal differentiation and induces apoptosis in the human squamous cell carcinoma HN5., PMID:9664130
Eradication of established tumors by a fully human monoclonal antibody to the epidermal growth factor receptor without concomitant chemotherapy., PMID:10096554
The rationale and strategy used to develop a series of highly potent, irreversible, inhibitors of the epidermal growth factor receptor family of tyrosine kinases., PMID:10495354
Ionizing radiation-induced mitogen-activated protein (MAP) kinase activation in DU145 prostate carcinoma cells: MAP kinase inhibition enhances radiation-induced cell killing and G2/M-phase arrest., PMID:10760996
Gastrin-releasing peptide receptor mediates activation of the epidermal growth factor receptor in lung cancer cells., PMID:15967120
Survivin contributes to the anti-apoptotic activities of transforming growth factor alpha in mouse blastocysts through phosphatidylinositol 3'-kinase pathway., PMID:16079309
Differential gene expression analysis reveals generation of an autocrine loop by a mutant epidermal growth factor receptor in glioma cells., PMID:16424019
Tumor necrosis factor regulation of apoptosis in mouse preimplantation embryos and its antagonism by transforming growth factor alpha/phosphatidylionsitol 3-kinase signaling system., PMID:17182889
TGF alpha has low protein expression in nonsyndromic clefts., PMID:17993868
[Connective tissue growth factors, CTGF and Cyr61 in drug-induced gingival overgrowth--an animal model]., PMID:20209781
Ethanol-TGFalpha-MEK signaling promotes growth of human hepatocellular carcinoma., PMID:19321179
Anti-IL5 decreases the number of eosinophils but not the severity of dermatitis in Sharpin-deficient mice., PMID:19650867
Epidermal growth factor receptor intron 1 CA dinucleotide repeat polymorphism and survival of advanced gastric cancer patients treated with cetuximab plus modified FOLFOX6., PMID:20047592
[Expressions of receptor tyrosine kinases mRNA and protein in carcinoma of bladder]., PMID:21906447
Biomarkers of benefit from cetuximab-based therapy in metastatic colorectal cancer: interaction of EGFR ligand expression with RAS/RAF, PIK3CA genotypes., PMID:23374602
44-plex cytokine profile of cholesteatoma., PMID:24256045
Infliximab restores the dysfunctional matrix remodeling protein and growth factor gene expression in patients with inflammatory bowel disease., PMID:24378596
Generation and activity of a humanized monoclonal antibody that selectively neutralizes the epidermal growth factor receptor ligands transforming growth factor-α and epiregulin., PMID:24518034
Gene expression markers of efficacy and resistance to cetuximab treatment in metastatic colorectal cancer: results from CALGB 80203 (Alliance)., PMID:25520391
Formation of vascular network structures within cardiac cell sheets from mouse embryonic stem cells., PMID:31245454
Genetic deletion of osteopontin in TRAMP mice skews prostate carcinogenesis from adenocarcinoma to aggressive human-like neuroendocrine cancers., PMID:26700622
MiR-374a suppresses lung adenocarcinoma cell proliferation and invasion by targeting TGFA gene expression., PMID:27207663
Role of TGF-alpha in the progression of diabetic kidney disease., PMID:28249836
Evaluation of the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy After Single and Multiple Dosings of LY3016859 in Healthy Subjects and Patients With Diabetic Nephropathy., PMID:29385323
Elevated serum eosinophil cationic protein and transforming growth factor-α levels in a patient with pemphigus vegetans., PMID:29862541
HER2 Activation Factors in Arsenite-Exposed Bladder Epithelial Cells., PMID:30137596
Mesothelin and TGF-α predict pancreatic cancer cell sensitivity to EGFR inhibitors and effective combination treatment with trametinib., PMID:30921351
Glucocorticoid Receptor Modulates EGFR Feedback upon Acquisition of Resistance to Monoclonal Antibodies., PMID:31052457
Development and Validation of a Test to Monitor Endoscopic Activity in Patients With Crohn's Disease Based on Serum Levels of Proteins., PMID:31711925
The dichotomous role of epiregulin in pain., PMID:31917773
The epigenetic treatment remodel genome-wide histone H4 hyper-acetylation patterns and affect signaling pathways in acute promyelocytic leukemia cells., PMID:33045196
Ovarian cancer cells direct monocyte differentiation through a non-canonical pathway., PMID:33069212
Menetrier's disease. A diagnostic and therapeutic challenge., PMID:34137712
Altered proTGFα/cleaved TGFα ratios offer new therapeutic strategies in renal carcinoma., PMID:34399807
Long-Term Elevated Inflammatory Protein Levels in Asymptomatic SARS-CoV-2 Infected Individuals., PMID:34603283
Identification of Growth Factors, Cytokines and Mediators Regulated by Artemisia annua L. Polyphenols (pKAL) in HCT116 Colorectal Cancer Cells: TGF-β1 and NGF-β Attenuate pKAL-Induced Anticancer Effects via NF-κB p65 Upregulation., PMID:35163520
Hypoxia-inducible factor pathway genes predict survival in metastatic clear cell renal cell carcinoma., PMID:35973929
An antibody-drug conjugate targeting soluble and membrane-bound TGFα is effective against pancreatic tumors., PMID:40410803
For research use only. Not for human or drug use.
