Catalog No.
FHJ89824
Species reactivity
Human
Host species
Human
Isotype
IgG1, kappa
Clonality
Monoclonal
Conjugation
PerCP
Applications
FCM
Target
Activation-inducible TNFR family receptor, GITR, TNFRSF18, CD357, Tumor necrosis factor receptor superfamily member 18, AITR, Glucocorticoid-induced TNFR-related protein
Concentration
0.5 mg/ml
Endotoxin level
Please contact with the lab for this information.
Accession
Q9Y5U5
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.
Stability and Storage
Store at 4°C for 12 months. Protect from light. Do not freeze.
Clone ID
hu6C8
Note
For research use only.
Differential expression of SLAMS and other modulatory molecules by human plasma cells during normal maturation., PMID:20923684
New B-cell CD molecules., PMID:20933010
Analysis of HLDA9 mAbs on plasmacytoid dendritic cells., PMID:20933012
Agonist antibodies to TNFR molecules that costimulate T and NK cells., PMID:23460535
Activating Fc γ receptors contribute to the antitumor activities of immunoregulatory receptor-targeting antibodies., PMID:23897982
OX40 engagement depletes intratumoral Tregs via activating FcγRs, leading to antitumor efficacy., PMID:24732076
Authentic GITR Signaling Fails To Induce Tumor Regression unless Foxp3+ Regulatory T Cells Are Depleted., PMID:26423152
Harnessing co-stimulatory TNF receptors for cancer immunotherapy: Current approaches and future opportunities., PMID:28085016
GITR ligation enhances functionality of tumor-infiltrating T cells in hepatocellular carcinoma., PMID:30719701
HERA-GITRL activates T cells and promotes anti-tumor efficacy independent of FcγR-binding functionality., PMID:31324216
OX40/OX40 ligand and its role in precision immune oncology., PMID:38526805