Catalog No.
FHJ35114
Species reactivity
Human
Host species
Mouse
Isotype
IgG1, kappa
Clonality
Monoclonal
Conjugation
PerCP
Applications
FCM
Target
HVEA, HVEM, Herpes virus entry mediator A, Tumor necrosis factor receptor superfamily member 14, Tumor necrosis factor receptor-like 2, HveA, TNFRSF14, CD270, TR2, Herpesvirus entry mediator A
Concentration
0.5 mg/ml
Endotoxin level
Please contact with the lab for this information.
Accession
Q92956
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.
Stability and Storage
Store at 4°C for 12 months. Protect from light. Do not freeze.
Clone ID
36H12
Note
For research use only.
Attenuation of graft arterial disease by manipulation of the LIGHT pathway., PMID:15178556
LIGHT costimulates CD40 triggering and induces immunoglobulin secretion; a novel key partner in T cell-dependent B cell terminal differentiation., PMID:15549770
Herpes simplex virus entry mediator associates in infected cells in a complex with viral proteins gD and at least gH., PMID:15767456
LIGHT enhances the bactericidal activity of human monocytes and neutrophils via HVEM., PMID:16275888
Herpes virus entry mediator synergizes with Toll-like receptor mediated neutrophil inflammatory responses., PMID:17067315
LIGHT up-regulated on B lymphocytes and monocytes in rheumatoid arthritis mediates cellular adhesion and metalloproteinase production by synoviocytes., PMID:17393389
Signaling pathway used by HSV-1 to induce NF-kappaB activation: possible role of herpes virus entry receptor A., PMID:17405920
PD-1/PD-L1, PD-1/PD-L2, and other co-inhibitory signaling pathways in transplantation., PMID:18662368
Involvement of HVEM receptor in activation of nuclear factor kappaB by herpes simplex virus 1 glycoprotein D., PMID:18671825
Construction of a fully retargeted herpes simplex virus 1 recombinant capable of entering cells solely via human epidermal growth factor receptor 2., PMID:18684832
Involvement of gD/HVEM interaction in NF-kB-dependent inhibition of apoptosis by HSV-1 gD., PMID:18723002
Role of nectin-1, HVEM, and PILR-alpha in HSV-2 entry into human retinal pigment epithelial cells., PMID:19234349
Characterization of herpes virus entry mediator as a factor linked to obesity., PMID:19680232
High expression of the inhibitory receptor BTLA in T-follicular helper cells and in B-cell small lymphocytic lymphoma/chronic lymphocytic leukemia., PMID:19762537
Acquired TNFRSF14 mutations in follicular lymphoma are associated with worse prognosis., PMID:20884631
Differential expression of SLAMS and other modulatory molecules by human plasma cells during normal maturation., PMID:20923684
New B-cell CD molecules., PMID:20933010
Analysis of HLDA9 mAbs on plasmacytoid dendritic cells., PMID:20933012
Immunohistochemical analysis of HLDA9 Workshop antibodies against cell-surface molecules in reactive and neoplastic lymphoid tissues., PMID:20946916
Expression profiles of novel cell surface molecules on B-cell subsets and plasma cells as analyzed by flow cytometry., PMID:20951740
Members 6B and 14 of the TNF receptor superfamily in multiple sclerosis predisposition., PMID:20962851
Lymphotoxin α stimulates proliferation and pro-inflammatory cytokine secretion of rheumatoid arthritis synovial fibroblasts., PMID:21111629
GPI-anchored protein-deficient T cells in patients with aplastic anemia and low-risk myelodysplastic syndrome: implications for the immunopathophysiology of bone marrow failure., PMID:21166881
Herpes simplex virus type-1 (HSV-1) entry into human mesenchymal stem cells is heavily dependent on heparan sulfate., PMID:21799659
Molecular basis for herpesvirus entry mediator recognition by the human immune inhibitory receptor CD160 and its relationship to the cosignaling molecules BTLA and LIGHT., PMID:21959263
Multiple inhibitory ligands induce impaired T-cell immunologic synapse function in chronic lymphocytic leukemia that can be blocked with lenalidomide: establishing a reversible immune evasion mechanism in human cancer., PMID:22547582
B and T lymphocyte attenuator mediates inhibition of tumor-reactive CD8+ T cells in patients after allogeneic stem cell transplantation., PMID:22634623
The intrahepatic expression and distribution of BTLA and its ligand HVEM in patients with HBV-related acute-on-chronic liver failure., PMID:23067542
Application of monoclonal antibodies in a sandwich enzyme-linked immunosorbent assay for identification and detection of soluble human B and T lymphocyte attenuator., PMID:23244320
Serum-soluble herpes virus entry mediator levels reflect disease severity and Th2 environment in cutaneous T-cell lymphoma., PMID:23306973
Structural basis for the antibody neutralization of herpes simplex virus., PMID:24100313
Cell surface phenotype profiles distinguish stable and progressive chronic lymphocytic leukemia., PMID:24289109
CD160 isoforms and regulation of CD4 and CD8 T-cell responses., PMID:25179432
The Tumor Necrosis Factor Superfamily Molecule LIGHT Promotes Keratinocyte Activity and Skin Fibrosis., PMID:25789702
Increased Heterologous Protein Expression in Drosophila S2 Cells for Massive Production of Immune Ligands/Receptors and Structural Analysis of Human HVEM., PMID:26202493
Rubinstein-Taybi syndrome - a window into follicular lymphoma biology., PMID:27086936
B-Lymphoblastic Lymphomas Evolving from Follicular Lymphomas Co-Express Surrogate Light Chains and Mutated Gamma Heavy Chains., PMID:27750045
A herpesvirus entry mediator mutein with selective agonist action for the inhibitory receptor B and T lymphocyte attenuator., PMID:29061848
LIGHT-HVEM signaling in keratinocytes controls development of dermatitis., PMID:29339444
The immune checkpoint, HVEM may contribute to immune escape in non-small cell lung cancer lacking PD-L1 expression., PMID:30429008
Soluble Fc-Disabled Herpes Virus Entry Mediator Augments Activation and Cytotoxicity of NK Cells by Promoting Cross-Talk between NK Cells and Monocytes., PMID:30770415
Prediction of steroid demand in the treatment of patients with ulcerative colitis by immunohistochemical analysis of the mucosal microenvironment and immune checkpoint: role of macrophages and regulatory markers in disease severity., PMID:30990953
Significance of Herpesvirus Entry Mediator Expression in Human Colorectal Liver Metastasis., PMID:31313042
Expression of herpesvirus entry mediator gene as a potential biomarker for disease severity in patients with persistent asthma., PMID:32045312
Circulating tumor DNA predicts response in Chinese patients with relapsed or refractory classical hodgkin lymphoma treated with sintilimab., PMID:32304999
BTLA/HVEM Axis Induces NK Cell Immunosuppression and Poor Outcome in Chronic Lymphocytic Leukemia., PMID:33917094
Virtual Evolution of HVEM Segment for Checkpoint Inhibitor Discovery., PMID:34205742
Genetic deletion of HVEM in a leukemia B cell line promotes a preferential increase of PD-1- stem cell-like T cells over PD-1+ T cells curbing tumor progression., PMID:37033927
Targeting BTLA with the peptide inhibitor HVEM(14-39) - A new way to restore the activity of T cells in melanoma., PMID:38733770
CD34+ and CD34- MM cells show different immune-checkpoint molecule expression profiles: high expression of CD112 and CD137 ligand on CD34+ MM cells., PMID:39531203
For research use only. Not for human or drug use.
