Dissection of agonistic and blocking effects of CD200 receptor antibodies., PMID:23691022
Anti-CD200R2, anti-IL-9, anti-IL-35, or anti-TGF-β abolishes increased graft survival and Treg induction induced in cromolyn-treated CD200R1KO.CD200tg mice., PMID:24142033
The CD200-CD200R1 inhibitory signaling pathway: immune regulation and host-pathogen interactions., PMID:24388216
The CD200-CD200 receptor inhibitory axis controls arteriogenesis and local T lymphocyte influx., PMID:24897500
Aberrant CD200/CD200R1 expression and its potential role in Th17 cell differentiation, chemotaxis and osteoclastogenesis in rheumatoid arthritis., PMID:25261692
Comparison of immunity in mice cured of primary/metastatic growth of EMT6 or 4THM breast cancer by chemotherapy or immunotherapy., PMID:25409195
Local targeting of the CD200-CD200R axis does not promote corneal graft survival., PMID:25450061
The Receptor for the CD200 Tolerance-Signaling Molecule Associated with Successful Pregnancy is Expressed by Early-Stage Breast Cancer Cells in 80% of Patients and by Term Placental Trophoblasts., PMID:26011475
The CD200 tolerance-signaling molecule and its receptor, CD200R1, are expressed in human placental villus trophoblast and in peri-implant decidua by 5 weeks' gestation., PMID:26123445
Decreased expression of CD200R3 on mouse basophils as a novel marker for IgG1-mediated anaphylaxis., PMID:26417442
Evaluation of the antigenicity of hydrolyzed cow's milk protein formulas using the mouse basophil activation test., PMID:26626100
Involvement of the orexin/hypocretin system in the pharmacological effects induced by Δ(9) -tetrahydrocannabinol., PMID:26799708
CD200Fc reduces TLR4-mediated inflammatory responses in LPS-induced rat primary microglial cells via inhibition of the NF-κB pathway., PMID:26956766
Immune checkpoint inhibitors enhance cytotoxicity of cytokine-induced killer cells against human myeloid leukaemic blasts., PMID:26961084
Characterization of CD200 Ectodomain Shedding., PMID:27111430
[CD200/CD200R Expression Levels and Its Significance after Allogeneic Hematopoietic Stem Cell Transplantation]., PMID:27342516
Impact of CD200-Fc on dendritic cells in lupus-prone NZB/WF1 mice., PMID:27545083
CD200Fc attenuates inflammatory responses and maintains barrier function by suppressing NF-κB pathway in cigarette smoke extract induced endothelial cells., PMID:27710895
Reduced expression of monocyte CD200R is associated with enhanced proinflammatory cytokine production in sarcoidosis., PMID:27929051
A comparison of serum miRNAs influencing metastatic growth of EMT6 vs 4THM tumor cells in wild-type and CD200R1KO mice., PMID:28160157
Monocytes, microglia, and CD200-CD200R1 signaling are essential in the transmission of inflammation from the periphery to the central nervous system., PMID:28164283
Importance of CD200 expression by tumor or host cells to regulation of immunotherapy in a mouse breast cancer model., PMID:28234914
Impact of antibody subclass and disulfide isoform differences on the biological activity of CD200R and βklotho agonist antibodies., PMID:28363871
CD200Fc reduces LPS-induced IL-1β activation in human cervical cancer cells by modulating TLR4-NF-κB and NLRP3 inflammasome pathway., PMID:28402258
Anti-inflammation conferred by stimulation of CD200R1 via Dok1 pathway in rat microglia after germinal matrix hemorrhage., PMID:28792282
CD200 modulates spinal cord injury neuroinflammation and outcome through CD200R1., PMID:29870752
Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer., PMID:30179225
CD200Fc Improves Neurological Function by Protecting the Blood-brain Barrier after Intracerebral Hemorrhage., PMID:31208229
Analysis of the expression of porcine CD200R1 and CD200R1L by using newly developed monoclonal antibodies., PMID:31233758
Bone marrow-mesenchymal stem cells modulate microglial activation in the peri-infarct area in rats during the acute phase of stroke., PMID:31589902
TAK-925, an orexin 2 receptor-selective agonist, shows robust wake-promoting effects in mice., PMID:31654653
Increased CD200 levels in peripheral blood mononuclear cells of patients with primary Sjögren's syndrome., PMID:32180363
Activation of pro- and anti-inflammatory responses in lung tissue injury during the acute phase of PRRSV-1 infection with the virulent strain Lena., PMID:32605751
The CD200R1 microglial inhibitory receptor as a therapeutic target in the MPTP model of Parkinson's disease., PMID:33823877
CD200R1L is a functional evolutionary conserved activating receptor in human neutrophils., PMID:33884657
CD200R1 and CD200R1L expression is regulated during B cell development in swine and modulates the Ig production in response to the TLR7 ligand imiquimoid., PMID:33961666
Soporific effect of modified Suanzaoren Decoction on mice models of insomnia by regulating Orexin-A and HPA axis homeostasis., PMID:34509822
CD200R family receptors are expressed on porcine monocytes and modulate the production of IL-8 and TNF-α triggered by TLR4 or TLR7 in these cells., PMID:35231818
CD200R1 Contributes to Successful Functional Reinnervation after a Sciatic Nerve Injury., PMID:35681481
Reduced cutaneous CD200:CD200R1 signaling in psoriasis enhances neutrophil recruitment to skin., PMID:35759230
Transcriptome analysis of Homo sapiens and Mus musculus reveals mechanisms of CD8+ T cell exhaustion caused by different factors., PMID:36084049
23ME-00610, a genetically informed, first-in-class antibody targeting CD200R1 to enhance antitumor T cell function., PMID:37288324
Different mechanisms of CD200-CD200R induce diverse outcomes in cancer treatment., PMID:37734537
Activation of the CD200/CD200R1 axis attenuates neuroinflammation and improves postoperative cognitive dysfunction via the PI3K/Akt/NF-κB signaling pathway in aged mice., PMID:37902837
Activation of the CD200/CD200R1 axis improves cognitive impairment by enhancing hippocampal neurogenesis via suppression of M1 microglial polarization and neuroinflammation in hypoxic-ischemic neonatal rats., PMID:38237226
Endothelial Cell-Derived Soluble CD200 Determines the Ability of Immune Cells to Cross the Blood-Brain Barrier., PMID:39273210
CD200R1 immune checkpoint blockade by the first-in-human anti-CD200R1 antibody 23ME-00610: molecular mechanism and engineering of a surrogate antibody., PMID:39402718
First-in-Human Study of 23ME-00610, an Antagonistic Antibody for Genetically Validated CD200R1 Immune Checkpoint, in Participants with Advanced Solid Malignancies., PMID:39651931
Monocytes from patients with myelodysplastic syndrome inhibit natural killer cell-mediated antitumor function through the CD200/CD200R pathway., PMID:40049088
Ucenprubart is an agonistic antibody to CD200R with the potential to treat inflammatory skin disease: preclinical development and a phase 1 clinical study., PMID:40312358
For research use only. Not for human or drug use.
