FHD18024
Human
Mouse
IgG2a, kappa
Monoclonal
PerCP
ELISA, FCM
PRLR, PRL-R, Prolactin receptor
0.5 mg/ml
Please contact with the lab for this information.
Liquid
0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.
Store at 4°C for 12 months. Protect from light. Do not freeze.
SAA2060
For research use only.
Characterization of ductal and lobular breast carcinomas using novel prolactin receptor isoform specific antibodies., PMID:21144038
Heat stress abatement during the dry period influences metabolic gene expression and improves immune status in the transition period of dairy cows., PMID:21183020
Growth hormone signaling in human T47D breast cancer cells: potential role for a growth hormone receptor-prolactin receptor complex., PMID:21310852
Prolactin plays a stimulatory role in ovarian follicular development and egg laying in chicken hens., PMID:21600726
Distribution of prolactin receptors suggests an intraductal role for prolactin in the mouse and human mammary gland, a finding supported by analysis of signaling in polarized monolayer cultures., PMID:22081226
Autocrine prolactin induced by the Pten-Akt pathway is required for lactation initiation and provides a direct link between the Akt and Stat5 pathways., PMID:23028142
The role of prolactin receptor in GH signaling in breast cancer cells., PMID:23192981
Neutralization of prolactin receptor function by monoclonal antibody LFA102, a novel potential therapeutic for the treatment of breast cancer., PMID:23270929
Molecular pathways: blockade of the PRLR signaling pathway as a novel antihormonal approach for the treatment of breast and prostate cancer., PMID:23515410
Prolactin-induced prostate tumorigenesis., PMID:25472541
A genome-wide association study for clinical mastitis in first parity US Holstein cows using single-step approach and genomic matrix re-weighting procedure., PMID:25658712
The prolactin receptor as a therapeutic target in human diseases: browsing new potential indications., PMID:26063597
A Neutralizing Prolactin Receptor Antibody Whose In Vivo Application Mimics the Phenotype of Female Prolactin Receptor-Deficient Mice., PMID:26284426
Different intracellular signalling pathways triggered by an anti-prolactin receptor (PRLR) antibody: Implication for a signal-specific PRLR agonist., PMID:26526176
Role of abnormal anterior pituitary hormones-growth hormone and prolactin in active systemic lupus erythematosus., PMID:26770558
Development of a Novel, Anti-idiotypic Monoclonal Anti-prolactin Antibody That Mimics the Physiological Functions of Prolactin., PMID:26949959
Phase I Study of the Prolactin Receptor Antagonist LFA102 in Metastatic Breast and Castration-Resistant Prostate Cancer., PMID:27091421
Development of a new anti-prolactin receptor (PRLR) antibody, F56, which can serve as a PRLR antagonist., PMID:27829125
Bispecific Antibodies and Antibody-Drug Conjugates (ADCs) Bridging HER2 and Prolactin Receptor Improve Efficacy of HER2 ADCs., PMID:28108597
Prolactin has a pathogenic role in systemic lupus erythematosus., PMID:28130617
Preclinical Activity of the Novel Anti-Prolactin Receptor (PRLR) Antibody-Drug Conjugate REGN2878-DM1 in PRLR-Positive Breast Cancers., PMID:28377489
Internal image anti-idiotypic antibody: A new strategy for the development a new category of prolactin receptor (PRLR) antagonist., PMID:28412548
Prolactin receptor targeting in breast and prostate cancers: New insights into an old challenge., PMID:28549597
The role of the ovarian cycle and the effects of mitogen-induced cytokines on human prolactin gene expression in peripheral blood mononuclear cells., PMID:28972407
Subdomain 2, Not the Transmembrane Domain, Determines the Dimerization Partner of Growth Hormone Receptor and Prolactin Receptor., PMID:28977606
ImmunoPET Imaging of Endogenous and Transfected Prolactin Receptor Tumor Xenografts., PMID:29684277
Monoclonal Antibody Against Prolactin Receptor: A Randomized Placebo-Controlled Study Evaluating Safety, Tolerability, and Pharmacokinetics of Repeated Subcutaneous Administrations in Postmenopausal Women., PMID:29806538
Effects of Dietary Daidzein Supplementation on Reproductive Performance, Serum Hormones, and Reproductive-Related Genes in Rats., PMID:29899203
α-PD-1 therapy elevates Treg/Th balance and increases tumor cell pSmad3 that are both targeted by α-TGFβ antibody to promote durable rejection and immunity in squamous cell carcinomas., PMID:30832732
A novel bispecific antibody targeting CD3 and prolactin receptor (PRLR) against PRLR-expression breast cancer., PMID:32398042
A first-in-human, phase 1, dose-escalation study of ABBV-176, an antibody-drug conjugate targeting the prolactin receptor, in patients with advanced solid tumors., PMID:32524319
COMMD8 changes expression during initial phase of wasp venom immunotherapy., PMID:32559011
Phase I Study of LFA102 in Patients With Advanced Breast Cancer or Castration-resistant Prostate Cancer., PMID:32878811
Preparation of a Growth Hormone Receptor/Prolactin Receptor Bispecific Antibody Antagonist Which Exhibited Anti-Cancer Activity., PMID:33362552
Expression of long-form prolactin receptor is associated with lower disease-free and overall survival in node-negative breast cancer patients., PMID:33633970
Impairment of testes development in Yangzhou ganders by augmentation of leptin receptor signaling., PMID:34051590
ABBV-176, a PRLR antibody drug conjugate with a potent DNA-damaging PBD cytotoxin and enhanced activity with PARP inhibition., PMID:34107902
The Potential Prognostic and Therapeutic Implications of Prolactin Receptor and Growth Hormone-releasing Hormone Receptor Expression in Uterine Leiomyosarcomas., PMID:34856572
dPRLR causes differences in immune responses between early and late feathering chickens after ALV-J infection., PMID:34998433
The effects of prolactin receptor blockade in a murine endometriosis interna model., PMID:35084123
Isolation of Leydig cells from adult rat testes by magnetic-activated cell sorting protocol based on prolactin receptor expression., PMID:35735181
Prolactin receptor signaling: A novel target for cancer treatment - Exploring anti-PRLR signaling strategies., PMID:36714582
Prolactin and oxytocin: potential targets for migraine treatment., PMID:36967387
A precise molecular subtyping of ulcerative colitis reveals the immune heterogeneity and predicts clinical drug responses., PMID:37443022
The immunotoxin targeting PRLR increases tamoxifen sensitivity and enhances the efficacy of chemotherapy in breast cancer., PMID:38898487
Does the brain make prolactin?, PMID:39041379
Immunization with OPN5 increased seasonal degradation of reproductive activity in Magang ganders., PMID:39754930
Production and Functional Verification of 8-Gene (GGTA1, CMAH, β4GalNT2, hCD46, hCD55, hCD59, hTBM, hCD39)-Edited Donor Pigs for Xenotransplantation., PMID:40190036
Prolactin maintains the neonatal phenotype of enterocytes during lactation in newborn mice., PMID:40353577
A prolactin-targeting antibody to prevent stress-induced peripheral nociceptor sensitization and female postoperative pain., PMID:40354542
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