Catalog No.
YHB13601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Arg160
Predicted molecular weight
20.13 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O75293
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
GADD45B, Growth arrest and DNA damage-inducible protein GADD45 beta, Myeloid differentiation primary response protein MyD118, MYD118, Negative growth regulatory protein MyD118
Note
For research use only.
GADD45A and GADD45B as Novel Biomarkers Associated with Chromatin Regulators in Renal Ischemia-Reperfusion Injury., PMID:37511062
Expression of GADD45B in Renal Tissue of Children with IgA Nephropathy and Correlation with Mesangial Hypercellularity., PMID:37534585
GADD45B regulates the carcinogenesis process of chronic atrophic gastritis and the metabolic pathways of gastric cancer., PMID:37608794
Demonstration of the impact of COVID-19 on metabolic associated fatty liver disease by bioinformatics and system biology approach., PMID:37657050
Key Roles of p53 Signaling Pathway-Related Factors GADD45B and SERPINE1 in the Occurrence and Development of Gastric Cancer., PMID:37662480
Gadd45β is critical for regulation of type I interferon signaling by facilitating G3BP-mediated stress granule formation., PMID:37917584
Downregulation of Gadd45β alleviates osteoarthritis by repressing lipopolysaccharide-induced fibroblast-like synoviocyte inflammation, proliferation and migration., PMID:37988908
Has-miR-300-GADD45B promotes melanoma growth via cell cycle., PMID:38070141
Shikonin reactivates TSGs GADD45B and PPP3CC to block NSCLC cell proliferation and migration through JNK/P38/MAPK signaling pathways., PMID:38167059
The role of basic leucine zipper transcription factor E4BP4 in cancer: a review and update., PMID:38193973
Identifying hub genes of sepsis-associated and hepatic encephalopathies based on bioinformatic analysis-focus on the two common encephalopathies of septic cirrhotic patients in ICU., PMID:38212812
GADD45A: With or without you., PMID:38264852
Malignant peritoneal mesotheliomas of rats induced by multiwalled carbon nanotubes and amosite asbestos: transcriptome and epigenetic profiles., PMID:38297314
DNA hypomethylation-mediated upregulation of GADD45B facilitates airway inflammation and epithelial cell senescence in COPD., PMID:38342401
OCA-B/Pou2af1 is sufficient to promote CD4+ T cell memory and prospectively identifies memory precursors., PMID:38386711
Oncopig bladder cancer cells recapitulate human bladder cancer treatment responses in vitro., PMID:38469237
The Transcriptome of BT-20 Breast Cancer Cells Exposed to Curcumin Analog NC2603 Reveals a Relationship between EGR3 Gene Modulation and Cell Migration Inhibition., PMID:38543002
GADD45B in the ventral hippocampal CA1 modulates aversive memory acquisition and spatial cognition., PMID:38614306
A novel defined programmed cell death related gene signature for predicting the prognosis of serous ovarian cancer., PMID:38685095
STAU1 exhibits a dual function by promoting amyloidogenesis and tau phosphorylation in cultured cells., PMID:38729552
Transcriptome analysis of large yellow croaker (Larimichthys crocea) at different growth rates., PMID:38842792
Nono induces Gadd45b to mediate DNA repair., PMID:38843934
Combinatorial metabolomic and transcriptomic analysis of muscle growth in hybrid striped bass (female white bass Morone chrysops x male striped bass M. saxatilis)., PMID:38858615
Enriched environment treatment promotes neurofunctional recovery by regulating the ALK5/Smad2/3/Gadd45β signaling pathway in rats with cerebral ischemia /reperfusion injury., PMID:39025366
Perinatal protein malnutrition alters maternal behavior and leads to maladaptive stress response, neurodevelopmental delay and disruption on DNA methylation machinery in female mice offspring., PMID:39029339
Single-cell transcriptomic analysis of B cells reveals new insights into atypical memory B cells in COVID-19., PMID:39132689
Nebulized Lipopolysaccharide Causes Delayed Cortical Neuroinflammation in a Murine Model of Acute Lung Injury., PMID:39337602
EPO Deficiency Upregulates GADD45b/p38 MAPK Axis, Mediating Schizophrenia-Related Synaptic and Cognitive Impairments., PMID:39467064
Avian Pasteurella multocida induces chicken macrophage apoptosis by inhibiting the Zyxin-FAK-AKT-FoxO1/NF-κB axis., PMID:39510005
GADD45β-MTK1 signaling axis mediates oncogenic stress-induced activation of the p38 and JNK pathways., PMID:39526327
E2F3a activates Gadd45b gene expression through PPARα-mediated transcriptional regulation in hepatic cells., PMID:39537030
Ventral Hippocampal CA1 GADD45B Regulates Susceptibility to Social Stress by Influencing NMDA Receptor-Mediated Synaptic Plasticity., PMID:39602067
Identification and validation of apoptosis-related genes in acute myocardial infarction based on integrated bioinformatics methods., PMID:39650552
Contradictory Role of Gadd45β in Liver Diseases., PMID:39653679
Developing the new diagnostic model by integrating bioinformatics and machine learning for osteoarthritis., PMID:39695788
Potential Biomarkers in Myocardial Fibrosis: A Bioinformatic Analysis., PMID:39699450
Knockdown of ribosomal protein L22-like 1 arrests the cell cycle and promotes apoptosis in colorectal cancer., PMID:39737125
Gene Expression Profiles in Ovarian Cancer Tissues as a Potential Tool to Predict Platinum-based Chemotherapy Resistance., PMID:39740837
Identification and Validation of Pivotal Genes in Osteoarthritis Combined with WGCNA Analysis., PMID:39906135
Mitochondrial Oxidative Stress Related Diagnostic Model Accurately Assesses Rheumatoid Arthritis Risk Stratification and Immune Infiltration Characterization., PMID:39924845
Genome-wide DNA methylation regulation analysis provides novel insights on post-radiation breast cancer., PMID:39955415
Clustering Mycobacterium tuberculosis-specific CD154+CD4+ T cells for distinguishing tuberculosis disease from infection based on single-cell RNA-seq analysis., PMID:40010539
PANoptosis-related gene biomarkers in aortic dissection., PMID:40086567
Exploring the functional variations of key candidate genes affecting egg production by hypothalamic-pituitary-ovarian axis in chickens., PMID:40132314
A Novel Protein NAB1-356 Encoded by circRNA circNAB1 Mitigates Atrial Fibrillation by Reducing Inflammation and Fibrosis., PMID:40145839
Transcriptomic profiling of autophagy and apoptosis pathways in liver cancer cells treated with a new tyrosine kinase inhibitor PD161570., PMID:40242947
Integrated bioinformatic analysis identifies GADD45B as an immune-related prognostic biomarker in skin cutaneous melanoma., PMID:40350499
Luteolin ameliorates kainic acid-induced seizure by modulating GADD45B and reducing oxidative stress in hippocampal neurons., PMID:40441030
Inhibiting NLRP3/Caspase-1/GSDMD-Mediated Pyroptosis: A New Role of GADD45B's Role in Hypertriglyceridemia-Induced Acute Pancreatitis., PMID:40485526
Identification of genes associated with liver ischemia-reperfusion injury after liver transplantation by WGCNA and PPI network analyses., PMID:40505700
For research use only. Not for human or drug use.
