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Anti-Human CD276 Antibody (SAA0090), APC

Catalog #:   FHJ04013 Specific References (50) DATASHEET
Host species: Human
Isotype: IgG1, kappa
Applications: FCM
Accession: Q5ZPR3
Overview

Catalog No.

FHJ04013

Species reactivity

Human

Host species

Human

Isotype

IgG1, kappa

Clonality

Monoclonal

Conjugation

APC

Applications

FCM

Target

CD276, B7-H3, Costimulatory molecule, B7H3, 4Ig-B7-H3, B7 homolog 3, CD276 antigen

Concentration

0.5 mg/ml

Endotoxin level

Please contact with the lab for this information.

Accession

Q5ZPR3

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Stability and Storage

Store at 4°C for 12 months. Protect from light. Do not freeze.

Clone ID

SAA0090

Note

For research use only.

Data Image
References

Induction of NK cell reactivity against acute myeloid leukemia by Fc-optimized CD276 (B7-H3) antibody., PMID:38637557

B7-H3-Targeting Chimeric Antigen Receptors Epstein-Barr Virus-specific T Cells Provides a Tumor Agnostic Off-The-Shelf Therapy Against B7-H3-positive Solid Tumors., PMID:38717140

CD276 regulates the immune escape of esophageal squamous cell carcinoma through CXCL1-CXCR2 induced NETs., PMID:38724465

The bispecific B7H3xCD3 antibody CC-3 induces T cell immunity against bone and soft tissue sarcomas., PMID:38765008

Chimeric Antigen Receptor T Cell with an Inducible Caspase-9 Suicide Gene Eradicates Uveal Melanoma Liver Metastases via B7-H3 Targeting., PMID:38767611

Targeting both GD2 and B7-H3 using bispecific antibody improves tumor selectivity for GD2-positive tumors., PMID:38853889

Development of DNA aptamers targeting B7H3 by hybrid-SELEX: an alternative to antibodies for immuno-assays., PMID:38866941

Differential Immune Checkpoint Protein Expression in HNSCC: The Role of HGF/MET Signaling., PMID:39000441

Expression and Prognostic Value of a Novel B7-H3 (CD276) Antibody in Acute Myeloid Leukemia., PMID:39001517

CAR T-cells targeting FGFR4 and CD276 simultaneously show potent antitumor effect against childhood rhabdomyosarcoma., PMID:39043633

Diet restriction enhances the effect of immune checkpoint block by inhibiting the intratumoral mTORC1/B7-H3 axis., PMID:39132973

ITGB6 modulates resistance to anti-CD276 therapy in head and neck cancer by promoting PF4+ macrophage infiltration., PMID:39152118

A Dual-Payload Antibody-Drug Conjugate Targeting CD276/B7-H3 Elicits Cytotoxicity and Immune Activation in Triple-Negative Breast Cancer., PMID:39186778

B7 homolog 3 in pancreatic cancer., PMID:39193002

Genetically engineered CD276-anchoring biomimetic nanovesicles target senescent escaped tumor cells to overcome chemoresistant and immunosuppressive breast cancer., PMID:39226654

Multiplexed Spatial Imaging at the Single-Cell Level Reveals Mutually Exclusive Expression of B7 Family Proteins., PMID:39244158

B7-H3 promotes nasopharyngeal carcinoma progression by regulating CD8+ T cell exhaustion., PMID:39267471

A B7-H3-Targeted CD28 Bispecific Antibody Enhances the Activity of Anti-PD-1 and CD3 T-cell Engager Immunotherapies., PMID:39301613

Development of a Specifically Labeled 89Zr Antibody for the Noninvasive Imaging of Tumors Overexpressing B7-H3., PMID:39322604

Novel bispecific antibody-drug conjugate targeting PD-L1 and B7-H3 enhances antitumor efficacy and promotes immune-mediated antitumor responses., PMID:39357981

Targeting CD276 for T cell-based immunotherapy of breast cancer., PMID:39367484

Targeting overexpressed antigens in glioblastoma via CAR T cells with computationally designed high-affinity protein binders., PMID:39420062

Ultrasound Molecular Imaging Enhances High-Intensity Focused Ultrasound Ablation on Liver Cancer With B7-H3-Targeted Microbubbles., PMID:39431644

Preclinical evaluation of antigen-sensitive B7-H3-targeting nanobody-based CAR-T cells in glioblastoma cautions for on-target, off-tumor toxicity., PMID:39562005

Prognostic value of B7-H3 expression in metastatic renal cell carcinoma and its impact on immunotherapy response., PMID:39614178

Engineered oncolytic virus expressing B7H3-targeting BiTE enhances antitumor T-cell immune response., PMID:39615894

B7-H3 in glioblastoma and beyond: significance and therapeutic strategies., PMID:39664380

Assessment of targets of antibody drug conjugates in SCLC., PMID:39748112

Statins inhibit onco-dimerization of the 4Ig isoform of B7-H3., PMID:39763965

The inhibitory effects of nimotuzumab on CD276 expression and immune escape in head and neck squamous cell carcinoma: Insights into anticancer mechanisms., PMID:39778280

PRMT5-Mediated ALKBH5 Methylation Promotes Colorectal Cancer Immune Evasion via Increasing CD276 Expression., PMID:39781264

Engineered T cells secreting αB7-H3-αCD3 bispecific engagers for enhanced anti-tumor activity against B7-H3 positive multiple myeloma: a novel therapeutic approach., PMID:39806405

Unraveling the dynamics of B7-H3-targeting therapeutic antibodies in cancer through PET imaging and antibody pharmacokinetics., PMID:39814321

An immunohistochemical and molecular genetic study of 60 colorectal carcinoma brain metastases in pursuit of predictive biomarkers for cancer therapy., PMID:39824298

Lineage-dependence of the neuroblastoma surfaceome defines tumor cell state-dependent and independent immunotherapeutic targets., PMID:39825754

A humanized anti-b7h3×4-1BB bispecific antibody exerts potent antitumour effects through the activation of innate and adaptive immunity., PMID:39847994

Identification and characterization of CD83 and CD276 as markers of dendritic cells in olive flounder (Paralichthys olivaceus)., PMID:39848419

Novel B7-H3 CAR T cells show potent antitumor effects in glioblastoma: a preclinical study., PMID:39863300

B7-H3-liquid biopsy for the characterization and monitoring of the dynamic biology of prostate cancer., PMID:39914189

The AURKA inhibitor alters the immune microenvironment and enhances targeting B7-H3 immunotherapy in glioblastoma., PMID:39928563

Advances in adoptive cell therapies in small cell lung cancer., PMID:40160238

Molecular Imaging of B7-H3-Targeting Bispecific T Cell-Engaging Antibody MGD009 in Glioblastoma Models., PMID:40183579

B7H3 in Gastrointestinal Tumors: Role in Immune Modulation and Cancer Progression: A Review of the Literature., PMID:40214484

Codelivery of apigenin, FdUMP and CD276 antibody synergistic inhibit colorectal cancer by ferroptosis-apoptosis-pyroptosis and CD276 blockade., PMID:40224726

Targeting site-specific N-glycosylated B7H3 induces potent antitumor immunity., PMID:40229277

Biomarkers of response to antibody-drug conjugates (TROP2 and nectin-4) and the immune microenvironment (NKG7, PD-L1, and B7-H3) in penile squamous cell carcinoma., PMID:40327767

Actionable heterogeneity of hepatocellular carcinoma therapy-induced senescence., PMID:40374812

m276-SL-PBD eradicates tumors and instigates long-lasting tumor-free survival in Merkel cell carcinoma preclinical models., PMID:40384933

PARP inhibitors accumulate B7-H3 on fibroblasts via blocking autophagic flux to potentiate immune evasion in ovarian cancer., PMID:40497528

Utilization of universal-targeting mSA2 CAR-T cells for the treatment of glioblastoma., PMID:40518621

Datasheet
$ 292
Product specifications
50 T 292 100 T 484

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Anti-Human CD276 Antibody (SAA0090), APC [FHJ04013]
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