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Anti-Human TrkB /NTRK2 Antibody (SAA0477), APC

Catalog #:   FHH31813 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: ELISA, FCM
Accession: Q16620
Overview

Catalog No.

FHH31813

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Conjugation

APC

Applications

ELISA, FCM

Target

Neurotrophic tyrosine kinase receptor type 2, TrkB tyrosine kinase, GP145-TrkB, TRKB, NTRK2, Tropomyosin-related kinase B, BDNF/NT-3 growth factors receptor, Trk-B

Concentration

0.5 mg/ml

Endotoxin level

Please contact with the lab for this information.

Accession

Q16620

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Stability and Storage

Store at 4°C for 12 months. Protect from light. Do not freeze.

Clone ID

SAA0477

Note

For research use only.

Data Image
References

ProBDNF Dependence of LTD and Fear Extinction Learning in the Amygdala of Adult Mice., PMID:34470044

Infralimbic BDNF signaling is necessary for the beneficial effects of extinction on set shifting in stressed rats., PMID:34497360

The brain-derived neurotrophic factor prompts platelet aggregation and secretion., PMID:34546355

Identification of Trigeminal Sensory Neuronal Types Innervating Masseter Muscle., PMID:34580157

Localization of Neurotrophin Specific Trk Receptors in Mechanosensory Systems of Killifish (Nothobranchius guentheri)., PMID:34638748

Environmental Enrichment Induces Meningeal Niche Remodeling through TrkB-Mediated Signaling., PMID:34638999

Identification of TrkB Binders from Complex Matrices Using a Magnetic Drug Screening Nanoplatform., PMID:35006910

Involvement of the BDNF-TrkB-KCC2 pathway in neuropathic pain after brachial plexus avulsion., PMID:35106976

TrkB agonist antibody ameliorates fertility deficits in aged and cyclophosphamide-induced premature ovarian failure model mice., PMID:35177657

Tools for analysis and conditional deletion of subsets of sensory neurons., PMID:35233469

Body Weight-Supported Treadmill Training Ameliorates Motoneuronal Hyperexcitability by Increasing GAD-65/67 and KCC2 Expression via TrkB Signaling in Rats with Incomplete Spinal Cord Injury., PMID:35320460

Effects of Excessive Iodine on the BDNF-TrkB Signaling Pathway and Related Genes in Offspring of EAT Rats., PMID:35322353

Corticosterone antagonist or TrkB agonist attenuates schizophrenia-like behavior in a mouse model combining Bdnf-e6 deficiency and developmental stress., PMID:35789832

Actions of the TrkB Agonist Antibody ZEB85 in Regulating the Architecture and Synaptic Plasticity in Hippocampal Neurons., PMID:35845610

A Single Domain Shark Antibody Targeting the Transferrin Receptor 1 Delivers a TrkB Agonist Antibody to the Brain and Provides Full Neuroprotection in a Mouse Model of Parkinson's Disease., PMID:35890231

ERK1/2-dependent BDNF synthesis and signaling is required for the antidepressant effect of microglia stimulation., PMID:35995236

[Analgesic effect and mechanism of electroacupuncture on SNI rats based on microglia-BDNF-neuron signal]., PMID:36075600

New, potent, small molecule agonists of tyrosine kinase receptors attenuate dry eye disease., PMID:36091713

Neuroprotective effect of secukinumab against rotenone induced Parkinson's disease in rat model: Involvement of IL-17, HMGB-1/TLR4 axis and BDNF/TrKB cascade., PMID:36527875

Mechanistic study of Coriandrum sativum on neuritogenesis and synaptogenesis based on computationally guided in vitro analyses., PMID:36641106

Sensory innervation of masseter, temporal and lateral pterygoid muscles in common marmosets., PMID:36798270

EA participates in pain transition through regulating KCC2 expression by BDNF-TrkB in the spinal cord dorsal horn of male rats., PMID:36875547

Nerve growth factor promotes differentiation and protects the oligodendrocyte precursor cells from in vitro hypoxia/ischemia., PMID:36875668

Frequent Overexpression of HER3 in Brain Metastases from Breast and Lung Cancer., PMID:37036472

Bispecific antibody shuttles targeting CD98hc mediate efficient and long-lived brain delivery of IgGs., PMID:37162883

Redefining Autoimmune Disorders' Pathoetiology: Implications for Mood and Psychotic Disorders' Association with Neurodegenerative and Classical Autoimmune Disorders., PMID:37174637

Isolation of human pluripotent stem cell-derived sensory neuron subtypes by immunopanning., PMID:37206924

Regulation of Satiety by Bdnf-e2-Expressing Neurons through TrkB Activation in Ventromedial Hypothalamus., PMID:37238691

Downregulation of BDNF-TrkB signaling may contribute to the colonic motility disorders in mice with streptozocin-induced diabetes., PMID:37417388

Neuroprotective and Disease-Modifying Effects of the Triazinetrione ACD856, a Positive Allosteric Modulator of Trk-Receptors for the Treatment of Cognitive Dysfunction in Alzheimer's Disease., PMID:37446337

Are TrkB receptor agonists the right tool to fulfill the promises for a therapeutic value of the brain-derived neurotrophic factor?, PMID:37488840

The efficacy of a TrkB monoclonal antibody agonist in preserving the auditory nerve in deafened guinea pigs., PMID:37837701

Bispecific antibody shuttles targeting CD98hc mediate efficient and long-lived brain delivery of IgGs., PMID:37890480

The role of hypoxia and radiation in developing a CTCs-like phenotype in murine osteosarcoma cells., PMID:38033871

Distinctive mesenchymal-like neurofibroma stem cells shape NF1 clinical phenotypes controlled by BDNF microenvironment., PMID:38042136

Obligatory role of microglia-mobilized hippocampal CREB-BDNF signaling in the prophylactic effect of β-glucan on chronic stress-induced depression-like behaviors in mice., PMID:38142848

Sensory innervation of masseter, temporal and lateral pterygoid muscles in common marmosets., PMID:38155190

Genetic knockout of NTRK2 by CRISPR/Cas9 decreases neurogenesis and favors glial progenitors during differentiation of neural progenitor stem cells., PMID:38161998

Localization of truncated TrkB and co-expression with full-length TrkB in the cerebral cortex of adult mice., PMID:38335799

TrkB-BDNF Signalling and Arc/Arg3.1 Immediate Early Genes in the Anterior Cingulate Cortex and Hippocampus: Insights into Novel Memory Milestones Through Behavioural Tagging., PMID:38485841

A Four-Week High-Fat Diet Induces Anxiolytic-like Behaviors through Mature BDNF in the mPFC of Mice., PMID:38672038

Targeting TrkB-PSD-95 coupling to mitigate neurological disorders., PMID:38886937

BDNF/TrkB signalling, in cooperation with muscarinic signalling, retrogradely regulates PKA pathway to phosphorylate SNAP-25 and Synapsin-1 at the neuromuscular junction., PMID:39044222

Targeting NGF but not VEGFR1 or BDNF signaling reduces endometriosis-associated pain in mice., PMID:39142441

Developing a novel neutralizing monoclonal antibody against TrkB., PMID:39247456

A peptide encoded by upstream open reading frame of MYC binds to tropomyosin receptor kinase B and promotes glioblastoma growth in mice., PMID:39356747

Spitz Spindle Cell/Reed Nevus With SQSTM1 :: NTRK2 Fusion and Atypical Features in an Older Male Patient: A Case Report and Review of Literature., PMID:39980385

Comparative Radiotracing Quantifies Brain Cellular Uptake and Catabolism of Bispecific Antibodies Targeting Transferrin Receptor and CD98hc., PMID:40071777

Cetuximab and Paclitaxel Drug Response in Head and Neck Tumor Stem Cells., PMID:40149887

Immunotherapy against tau fragment diminishes AD pathology, improving synaptic function and cognition., PMID:40426267

Datasheet
$ 258
Product specifications
50 T 258 100 T 426

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Distributor list

For research use only. Not for human or drug use.

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Anti-Human TrkB /NTRK2 Antibody (SAA0477), APC [FHH31813]
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