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Anti-Human GAS6 Antibody (SAA0476), APC

Catalog #:   FHG78913 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: ELISA, FCM
Accession: Q14393
Overview

Catalog No.

FHG78913

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Conjugation

APC

Target

AXLLG, Growth arrest-specific protein 6, AXL receptor tyrosine kinase ligand, GAS6, GAS-6

Concentration

0.5 mg/ml

Endotoxin level

Please contact with the lab for this information.

Accession

Q14393

Applications

ELISA, FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Stability and Storage

Store at 4°C for 12 months. Protect from light. Do not freeze.

Clone ID

SAA0476

Data Image
References

Electrochemical immunosensing for rapid glaucoma disease diagnosis through simultaneous determination of SPP1 and GAS6 proteins in ocular fluids., PMID:40494269

Vitamin K supports TGF-β1 depended in vitro human Langerhans cell differentiation and function via Axl., PMID:40040711

Phosphatidylserine (PS)-targeting chimeric Interferon (IFN) fusion proteins for anti-tumor applications., PMID:39896467

Stress-experienced monocytes/macrophages lose anti-inflammatory function via β2-adrenergic receptor in skin allergic inflammation., PMID:39566608

AXL-specific single domain antibodies show diagnostic potential and anti-tumor activity in Acute Myeloid Leukemia., PMID:38773967

CD147 Sparks Atherosclerosis by Driving M1 Phenotype and Impairing Efferocytosis., PMID:38166463

Targeting GAS6/AXL signaling improves the response to immunotherapy by restoring the anti-immunogenic tumor microenvironment in gastric cancer., PMID:37952835

Altered expression of AXL receptor tyrosine kinase in gastrointestinal cancers: a promising therapeutic target., PMID:37469409

A procedure for producing an anti-AXL nanobody in E. coli., PMID:37023993

AXL Inhibitors: Status of Clinical Development., PMID:36920638

Microbiota-dependent and -independent postnatal development of salivary immunity., PMID:36640306

Anti-inflammatory clearance of amyloid-β by a chimeric Gas6 fusion protein., PMID:35927581

AXL targeting by a specific small molecule or monoclonal antibody inhibits renal cell carcinoma progression in an orthotopic mice model., PMID:34877810

Interruption of neutrophil extracellular traps formation dictates host defense and tubular HOXA5 stability to augment efficacy of anti-Fn14 therapy against septic AKI., PMID:34646379

AXL Receptor in Cancer Metastasis and Drug Resistance: When Normal Functions Go Askew., PMID:34638349

Tuo-Min-Ding-Chuan Decoction Alleviate Ovalbumin-Induced Allergic Asthma by Inhibiting Mast Cell Degranulation and Down-Regulating the Differential Expression Proteins., PMID:34630102

Anti-Axl monoclonal antibodies attenuate the migration of MDA-MB-231 breast cancer cells., PMID:34539853

Advances in the treatment of platinum resistant epithelial ovarian cancer: an update on standard and experimental therapies., PMID:34082614

Biparatopic single-domain antibodies against Axl achieve ultra-high affinity through intramolecular engagement., PMID:34058562

Ligand-dependent kinase activity of MERTK drives efferocytosis in human iPSC-derived macrophages., PMID:34035216

MERTK Inhibition: Potential as a Treatment Strategy in EGFR Tyrosine Kinase Inhibitor-Resistant Non-Small Cell Lung Cancer., PMID:33562150

Systemic inflammation is a determinant of outcomes of CD40 agonist-based therapy in pancreatic cancer patients., PMID:33497362

TAM receptors: A phosphatidylserine receptor family and its implications in viral infections., PMID:33234246

Anti-Axl antibody treatment reduces the severity of experimental autoimmune encephalomyelitis., PMID:33121494

Selective Increment of Synovial Soluble TYRO3 Correlates with Disease Severity and Joint Inflammation in Patients with Rheumatoid Arthritis., PMID:32964059

CD14+CD16- monocytes are the main precursors of osteoclasts in rheumatoid arthritis via expressing Tyro3TK., PMID:32958023

Gas6 Induces Myelination through Anti-Inflammatory IL-10 and TGF-β Upregulation in White Matter and Glia., PMID:32722558

Interaction with CD68 and Regulation of GAS6 Expression by Endosialin in Fibroblasts Drives Recruitment and Polarization of Macrophages in Hepatocellular Carcinoma., PMID:32591411

Heme oxygenase-1 inhibition mediates Gas6 to enhance bortezomib-sensitivity in multiple myeloma via ERK/STAT3 axis., PMID:32298237

Possible Association of Elevated Plasma Levels of Growth Arrest-Specific Protein 6 and the Soluble Form of Tyrosine Kinase Receptor Axl with Low Hepatitis C Viral Load in Patients with Type 2 Diabetes Mellitus., PMID:31905327

AXL receptor tyrosine kinase as a promising anti-cancer approach: functions, molecular mechanisms and clinical applications., PMID:31684958

Increased sMer, but not sAxl, sTyro3, and Gas6 relate with active disease in juvenile systemic lupus erythematosus., PMID:31655933

Target-Mediated Drug Disposition Pharmacokinetic/Pharmacodynamic Model-Informed Dose Selection for the First-in-Human Study of AVB-S6-500., PMID:31599479

Macrophage phenotypes and Gas6/Axl signaling in apical lesions., PMID:31528256

Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner., PMID:31285764

Engineered AXL-ECD-Fc variants that abolish the AXL/Gas6 interaction suppress tumor cell migration., PMID:31186805

Growth arrest-specific protein 6 (Gas6) attenuates inflammatory injury and apoptosis in iodine-induced NOD.H-2h4 mice., PMID:31129420

A novel human anti-AXL monoclonal antibody attenuates tumour cell migration., PMID:31075180

Pan-TAM Tyrosine Kinase Inhibitor BMS-777607 Enhances Anti-PD-1 mAb Efficacy in a Murine Model of Triple-Negative Breast Cancer., PMID:30877108

Differential Interaction of Platelet-Derived Extracellular Vesicles With Circulating Immune Cells: Roles of TAM Receptors, CD11b, and Phosphatidylserine., PMID:30619243

Tyro3, Axl, and Mertk receptors differentially participate in platelet activation and thrombus formation., PMID:30541554

Targeted inhibition of Axl receptor tyrosine kinase ameliorates anti-GBM-induced lupus-like nephritis., PMID:29895432

Proseek single-plex protein assay kit system to detect sAxl and Gas6 in serological material of brain tumor patients., PMID:29876303

Targeting of TAM Receptors Ameliorates Fibrotic Mechanisms in Idiopathic Pulmonary Fibrosis., PMID:29634284

Axl and MerTK receptor tyrosine kinases maintain human macrophage efferocytic capacity in the presence of viral triggers., PMID:29400409

Antiphospholipid Antibodies Inhibit Trophoblast Toll-Like Receptor and Inflammasome Negative Regulators., PMID:29342502

Inhibition of type I interferon responses by adenovirus serotype-dependent Gas6 binding., PMID:29288958

A critical role of Gas6/Axl signal in allergic airway responses during RSV vaccine-enhanced disease., PMID:28722020

Gas6 Promotes Inflammatory (CCR2hiCX3CR1lo) Monocyte Recruitment in Venous Thrombosis., PMID:28450294

Axl acts as a tumor suppressor by regulating LIGHT expression in T lymphoma., PMID:28423548

Datasheet
$ 258
Product specifications
50 T 258 100 T 426

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For research use only. Not for human or drug use.

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Anti-Human GAS6 Antibody (SAA0476), APC [FHG78913]
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