The methyltransferase METTL3 promotes tumorigenesis via mediating HHLA2 mRNA m6A modification in human renal cell carcinoma., PMID:35794583
KIR3DL3-HHLA2 and TMIGD2-HHLA2 pathways: The dual role of HHLA2 in immune responses and its potential therapeutic approach for cancer immunotherapy., PMID:35933091
HHLA2 predicts improved prognosis of anti-PD-1/PD-L1 immunotherapy in patients with melanoma., PMID:36003385
Novel immune scoring dynamic nomograms based on B7-H3, B7-H4, and HHLA2: Potential prediction in survival and immunotherapeutic efficacy for gallbladder cancer., PMID:36159808
Single-cell RNA sequencing highlights the functional role of human endogenous retroviruses in gallbladder cancer., PMID:36374772
Protocol for evaluating antitumor activity of KIR3DL3 blockade in an NK cell-based xenogeneic lung tumor model., PMID:36386885
The Correlation of Ten Immune Checkpoint Gene Expressions and Their Association with Gastric Cancer Development., PMID:36430322
B7 Family Members in Pancreatic Ductal Adenocarcinoma: Attractive Targets for Cancer Immunotherapy., PMID:36499340
Silencing tumor-intrinsic HHLA2 potentiates the anti-tumoral effect of paclitaxel on MG63 cells: Another side of immune checkpoint., PMID:36535461
Increased co-expression of stromal HHLA2 and fibroblast activation protein in upper tract urothelial carcinoma., PMID:36598731
Construction and Validation of a Novel Immune Checkpoint-Related Model in Clear Cell Renal Cell Carcinoma., PMID:36618968
Immunosuppression by Inflammation-Stimulated Amplification of Myeloid-Derived Suppressor Cells and Changes in Expression of Immune Checkpoint HHLA2 in Chronic Obstructive Pulmonary Disease., PMID:36846109
Integrative analyses identify CD73 as a prognostic biomarker and immunotherapeutic target in intrahepatic cholangiocarcinoma., PMID:36899373
Overexpression and Role of HHLA2, a Novel Immune Checkpoint, in Colorectal Cancer., PMID:36982953
Transcriptome profiling reveals transcriptional regulation of VISTA in T cell activation., PMID:37004501
HHLA2 immune-regulatory roles in cancer., PMID:37011487
Recent advancements in the B7/CD28 immune checkpoint families: new biology and clinical therapeutic strategies., PMID:37069229
A new prediction model of hepatocellular carcinoma based on N7-methylguanosine modification., PMID:37081394
The Identification and Clinical Value Evaluation of CYCS Related to Asthma through Bioinformatics Analysis and Functional Experiments., PMID:37091894
Presence of PD-1 similarity genes in monocytes may promote the development of type 1 diabetes mellitus and poor prognosis of pancreatic cancer., PMID:37130628
Downregulation of HHLA2 inhibits ovarian cancer progression via the NF-κB signaling pathway and suppresses the expression of CA9., PMID:37210768
CancerHERVdb: Human Endogenous Retrovirus (HERV) Expression Database for Human Cancer Accelerates Studies of the Retrovirome and Predictions for HERV-Based Therapies., PMID:37255431
B7-H7: A potential target for cancer immunotherapy., PMID:37290327
Polymorphic KIR3DL3 expression modulates tissue-resident and innate-like T cells., PMID:37390222
Heterogeneous Expression of PD-L1, B7x, B7-H3, and HHLA2 in Pulmonary Sarcomatoid Carcinoma and the Related Regulatory Signaling Pathways., PMID:37444481
Role of Next Generation Immune Checkpoint Inhibitor (ICI) Therapy in Philadelphia Negative Classic Myeloproliferative Neoplasm (MPN): Review of the Literature., PMID:37569880
Analysis of a new therapeutic target and construction of a prognostic model for breast cancer based on ferroptosis genes., PMID:37643511
MUC16 stimulates neutrophils to an inflammatory and immunosuppressive phenotype in ovarian cancer., PMID:37644468
Regulation of HHLA2 expression in kidney cancer and myeloid cells., PMID:37891555
Seven chromatin regulators as immune cell infiltration characteristics, potential diagnostic biomarkers and drugs prediction in hepatocellular carcinoma., PMID:37903974
Novel immune checkpoint targets: A promising therapy for cancer treatments., PMID:37979454
Alternative immune checkpoints in immunoregulatory profile of cancer stem cells., PMID:38144305
Evaluation of HHLA2 and CD8 Immunohistochemical Expression in Colorectal Carcinoma and Their Prognostic Significance., PMID:38156868
Clinical Significance of HHLA2 as a Novel Therapeutic Target for Colorectal Cancer., PMID:38299402
HHLA2 is more significantly associated with poor prognosis in TSCC than PD-L1., PMID:38321252
The B7:CD28 family and friends: Unraveling coinhibitory interactions., PMID:38354702
Pharmacological suppression of HHLA2 glycosylation restores anti-tumor immunity in colorectal cancer., PMID:38522775
Down-regulated HHLA2 enhances neoadjuvant immunotherapy efficacy in patients with non-small cell lung cancer (NSCLC) with chronic obstructive pulmonary disease (COPD)., PMID:38553708
A radiomics signature derived from CT imaging to predict MSI status and immunotherapy outcomes in gastric cancer: a multi-cohort study., PMID:38561648
HHLA2 promotes hepatoma cell proliferation, migration, and invasion via SPP1/PI3K/AKT signaling pathway., PMID:38578157
Clinical Value of Human Endogenous Retrovirus-H Long Terminal Repeat Associating 2 (HHLA2) in Small Cell Lung Cancer., PMID:38613340
Prognostic Value of HHLA2 in Patients with Solid Tumors: A Meta-Analysis., PMID:38731979
HHLA2 deficiency inhibits pancreatic cancer progression and THP-1 macrophage M2 polarization via EGFR/MAPK/ERK and mTOR/AKT pathway., PMID:38762741
The Importance of HHLA2 in Solid Tumors-A Review of the Literature., PMID:38786018
Aberrant expression of B7-H4 and B7-H5 contributes to the development of cutaneous squamous cell carcinoma., PMID:38850312
Human endogenous retrovirus-H long terminal repeat-associating 2: an emerging immune checkpoint for cancer immunotherapy., PMID:38973642
HLA and KIR genetic association and NK cells in anti-NMDAR encephalitis., PMID:39050850
Correct stimulation of CD28H arms NK cells against tumor cells., PMID:39101623
Unlocking the potential of HHLA2: identifying functional immune infiltrating cells in the tumor microenvironment and predicting clinical outcomes in laryngeal squamous cell carcinoma., PMID:39105870
Multiplexed Spatial Imaging at the Single-Cell Level Reveals Mutually Exclusive Expression of B7 Family Proteins., PMID:39244158
For research use only. Not for human or drug use.
