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Anti-Human CSPG4/HMW-MAA/MCSP/NG2 Antibody (9.2.27#), FITC

Catalog #:   FHJ08361 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a
Applications: FCM, IF, WB
Accession: Q6UVK1
Overview

Catalog No.

FHJ08361

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a

Clonality

Monoclonal

Conjugation

FITC

Target

Chondroitin sulfate proteoglycan 4, CSPG4, Chondroitin sulfate proteoglycan NG2, MCSP, Melanoma chondroitin sulfate proteoglycan, Melanoma-associated chondroitin sulfate proteoglycan

Concentration

0.5 mg/ml

Endotoxin level

Please contact with the lab for this information.

Accession

Q6UVK1

Applications

FCM, IF, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Stability and Storage

Store at 4°C for 12 months. Protect from light. Do not freeze.

Clone ID

9.2.27#

Data Image
References

Chondroitin Sulfate Proteoglycan 4 (CSPG4) as an Emerging Target for Immunotherapy to Treat Melanoma., PMID:39409881

CSPG4-targeting CAR-macrophages inhibit melanoma growth., PMID:38895447

Chondroitin sulfate proteoglycan 4: An attractive target for antibody-based immunotherapy., PMID:38735753

MiR126-targeted-nanoparticles combined with PI3K/AKT inhibitor as a new strategy to overcome melanoma resistance., PMID:37990493

CSPG4 as a target for the specific killing of triple-negative breast cancer cells by a recombinant SNAP-tag-based antibody-auristatin F drug conjugate., PMID:37432459

Bispecific antibodies redirect synthetic agonistic receptor modified T cells against melanoma., PMID:37208128

Anti-cancer pro-inflammatory effects of an IgE antibody targeting the melanoma-associated antigen chondroitin sulfate proteoglycan 4., PMID:37185332

VT68.2: An Antibody to Chondroitin Sulfate Proteoglycan 4 (CSPG4) Displays Reactivity against a Tumor-Associated Carbohydrate Antigen., PMID:36768830

The role of pericytes on the efficacy of bevacizumab in colorectal cancer., PMID:36422502

Generation and Characterization of Native and Sialic Acid-Deficient IgE., PMID:36362241

The Potential of Antibody Technology and Silver Nanoparticles for Enhancing Photodynamic Therapy for Melanoma., PMID:36140259

Chondroitin sulfate proteoglycan 4 expression in chondrosarcoma: A potential target for antibody-based immunotherapy., PMID:36110930

Identification of Novel Retinal Pericyte-Targeting rAAV Vectors Through Directed Evolution., PMID:36018583

Immunotherapeutic Targeting of NG2/CSPG4 in Solid Organ Cancers., PMID:35891187

Antigen mimicry as an effective strategy to induce CSPG4-targeted immunity in dogs with oral melanoma: a veterinary trial., PMID:35580930

A proof-of-concept study on the use of a fluorescein-based 18F-tracer for pretargeted PET., PMID:35239034

Chondroitin sulfate proteoglycan 4, a targetable oncoantigen that promotes ovarian cancer growth, invasion, cisplatin resistance and spheroid formation., PMID:34942534

Receptor binding mechanisms of Clostridioides difficile toxin B and implications for therapeutics development., PMID:34862749

In vivo trafficking of a tumor-targeting IgE antibody: molecular imaging demonstrates rapid hepatobiliary clearance compared to IgG counterpart., PMID:34513315

A chondroitin sulfate proteoglycan 4‑specific monoclonal antibody inhibits melanoma cell invasion in a spheroid model., PMID:34318902

Structural basis for CSPG4 as a receptor for TcdB and a therapeutic target in Clostridioides difficile infection., PMID:34145250

Immunoaffinity-Based Isolation of Melanoma Cell-Derived and T Cell-Derived Exosomes from Plasma of Melanoma Patients., PMID:33704724

Proteomic profile of melanoma cell-derived small extracellular vesicles in patients' plasma: a potential correlate of melanoma progression., PMID:33613873

BNIP3L-mediated mitophagy is required for mitochondrial remodeling during the differentiation of optic nerve oligodendrocytes., PMID:33404293

Oligodendrocyte Lineage Marker Expression in eGFP-GFAP Transgenic Mice., PMID:33346907

Chondroitin Sulphate Proteoglycan 4 (NG2/CSPG4) Localization in Low- and High-Grade Gliomas., PMID:32599896

A Novel Antibody-Drug Conjugate (ADC) Delivering a DNA Mono-Alkylating Payload to Chondroitin Sulfate Proteoglycan (CSPG4)-Expressing Melanoma., PMID:32331483

In vivo safety profile of a CSPG4-directed IgE antibody in an immunocompetent rat model., PMID:31769737

Designed Ankyrin Repeat Protein (DARPin) Neutralizers of TcdB from Clostridium difficile Ribotype 027., PMID:31578248

Selection and characterization of ultrahigh potency designed ankyrin repeat protein inhibitors of C. difficile toxin B., PMID:31233493

Proteoglycans and glycosaminoglycans as regulators of cancer stem cell function and therapeutic resistance., PMID:31230410

Identification of CSPG4 as a promising target for translational combinatorial approaches in osteosarcoma., PMID:31217827

Bispecific Antibody Approach for Improved Melanoma-Selective PD-L1 Immune Checkpoint Blockade., PMID:31128201

Mesenchymal stromal cells for bone sarcoma treatment: Roadmap to clinical practice., PMID:30956944

Synergistic antitumor effects of 9.2.27-PE38KDEL and ABT-737 in primary and metastatic brain tumors., PMID:30625226

Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism., PMID:30340601

Enhanced targeting of triple-negative breast carcinoma and malignant melanoma by photochemical internalization of CSPG4-targeting immunotoxins., PMID:29565434

212Pb-Labeled Antibody 225.28 Targeted to Chondroitin Sulfate Proteoglycan 4 for Triple-Negative Breast Cancer Therapy in Mouse Models., PMID:29561763

Chondroitin Sulfate Proteoglycan 4 and Its Potential As an Antibody Immunotherapy Target across Different Tumor Types., PMID:29375561

Resident cell lineages are preserved in pulmonary vascular remodeling., PMID:29359814

Effects of chondroitin sulfate proteoglycan 4 (NG2/CSPG4) on soft-tissue sarcoma growth depend on tumor developmental stage., PMID:29196603

Human recombinant Fab fragment from combinatorial libraries of a B-cell lymphoma patient recognizes core protein of chondroitin sulphate proteoglycan 4., PMID:29036679

Selection of novel affinity-matured human chondroitin sulfate proteoglycan 4 antibody fragments by yeast display., PMID:28981720

Functional defects in Clostridium difficile TcdB toxin uptake identify CSPG4 receptor-binding determinants., PMID:28842504

CSPG4: A Target for Selective Delivery of Human Cytolytic Fusion Proteins and TRAIL., PMID:28657611

Immunomodulating and Immunoresistance Properties of Cancer-Initiating Cells: Implications for the Clinical Success of Immunotherapy., PMID:28287848

Development and validation of a cell-based fluorescent method for measuring antibody affinity., PMID:28024998

Isolating subpopulations of human epidermal basal cells based on polyclonal serum against trypsin-resistant CSPG4 epitopes., PMID:28011196

Roles of chondroitin sulfate proteoglycan 4 in fibrogenic/adipogenic differentiation in skeletal muscle tissues., PMID:27582000

Photoimmunotheranostic agents for triple-negative breast cancer diagnosis and therapy that can be activated on demand., PMID:27448975

Datasheet
$ 225
Product specifications
50 T 225 100 T 372

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Anti-Human CSPG4/HMW-MAA/MCSP/NG2 Antibody (9.2.27#), FITC [FHJ08361]
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