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Anti-Human CD18/ITGB2 Antibody (60.3), FITC

Catalog #:   FHC13141 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a
Applications: FCM, WB
Accession: P05107
Overview

Catalog No.

FHC13141

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a

Clonality

Monoclonal

Conjugation

FITC

Target

Complement receptor C3 subunit beta, Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta, Integrin beta-2, MFI7, CD18, ITGB2

Concentration

0.5 mg/ml

Endotoxin level

Please contact with the lab for this information.

Accession

P05107

Applications

FCM, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Stability and Storage

Store at 4°C for 12 months. Protect from light. Do not freeze.

Clone ID

60.3

Note

For research use only.

Data Image
References

Monocytes augment inflammatory responses in human aortic valve interstitial cells via β2-integrin/ICAM-1-mediated signaling., PMID:35411432

Using digital RNA counting to establish flow cytometry diagnostic criteria for subtypes of CD34+ canine acute leukaemia., PMID:35491468

Humanized β2 Integrin-Expressing Hoxb8 Cells Serve as Model to Study Integrin Activation., PMID:35563841

A humanized β2 integrin knockin mouse reveals localized intra- and extravascular neutrophil integrin activation in vivo., PMID:35649374

CD18 Mediates Neutrophil Imperviousness to the Aggregatibacter actinomycetemcomitans JP2 Clone in Molar-Incisor Pattern Periodontitis., PMID:35663998

Cancer cells resist antibody-mediated destruction by neutrophils through activation of the exocyst complex., PMID:35728876

Flow Cytometric Analysis of Leukocyte Populations in the Lung Tissue of Dromedary Camels., PMID:35737339

Structural basis for non-canonical integrin engagement by Bordetella adenylate cyclase toxin., PMID:35977491

β2-Integrin Adhesive Bond Tension under Shear Stress Modulates Cytosolic Calcium Flux and Neutrophil Inflammatory Response., PMID:36139397

B-cell receptor associated protein 31 deficiency decreases the expression of adhesion molecule CD11b/CD18 and PSGL-1 in neutrophils to ameliorate acute lung injury., PMID:36210579

Characterization of microglia/macrophage phenotypes in the spinal cord following intervertebral disc herniation., PMID:36262531

High-Dimensional Cytometry Dissects Immunological Fingerprints of Idiopathic Inflammatory Myopathies., PMID:36291195

Undifferentiated Wing Sarcoma in a Peach-Faced Lovebird (Agapornis roseicollis)., PMID:36335863

Integrin CD11b Contributes to Hypertension and Vascular Dysfunction Through Mediating Macrophage Adhesion and Migration., PMID:36377602

Immunosuppressive Effects of Annona muricata L. Leaf Extract on Cellular and Humoral Immune Responses in Male Wistar Rats., PMID:36545731

In-depth immunophenotyping reveals significant alteration of lymphocytes in buffalo with brucellosis., PMID:36602043

Neutrophil function following treatment of psoriatic arthritis patients with secukinumab: altered cytokine signalling but no impairment of host defence., PMID:36617171

Myo/Nog Cells Give Rise to Myofibroblasts During Epiretinal Membrane Formation in a Mouse Model of Proliferative Vitreoretinopathy., PMID:36723927

The CIS association of CD47 with integrin Mac-1 regulates macrophage responses by stabilizing the extended integrin conformation., PMID:36796515

Phenotyping and Genotyping of HNA: Prevalence, Risk of Alloimmunization, and HNA Incompatibilities in Indians., PMID:36818775

CD11b mediates hypertensive cardiac remodeling by regulating macrophage infiltration and polarization., PMID:36822392

Phagocytosis via complement receptor 3 enables microbes to evade killing by neutrophils., PMID:36882066

Allosteric targeting resolves limitations of earlier LFA-1 directed modalities., PMID:36921634

Modulating CD40 and integrin signaling in the proinflammatory nexus using a 15-amino-acid peptide, KGYY15., PMID:36944397

Mechano-Redox Control of Mac-1 De-Adhesion by PDI Promotes Directional Movement Under Flow., PMID:37021588

Regulation of coagulation activation in newly diagnosed AML by the heme enzyme myeloperoxidase., PMID:37473552

Polymorphonuclear phenotypical expression of CD18, at baseline and after in vitro activation, in several clinical disorders: Revision of our case series., PMID:37482987

Neutrophil attachment via Mac-1 (αMβ2; CD11b/CD18; CR3) integrins induces PAD4 deimination of profilin and histone H3., PMID:37778386

Analysis of cells of epithelial, connective tissue and immune differentiation in HPV-positive-, HPV-negative oropharyngeal carcinoma and normal oropharyngeal tissue by immunofluorescence multiplex image cytometry: a preliminary report., PMID:38012597

SIGLEC-5/14 Inhibits CD11b/CD18 Integrin Activation and Neutrophil-Mediated Tumor Cell Cytotoxicity., PMID:38138970

A Flow Cytometry-Based High-Throughput Technique for Screening Integrin-Inhibitory Drugs., PMID:38372326

The extracellular cyclophilin A-integrin β2 complex as a therapeutic target of viral pneumonia., PMID:38454605

SKAP2 acts downstream of CD11b/CD18 and regulates neutrophil effector function., PMID:38487529

The monocyte cell surface is a unique site of autoantigen generation in rheumatoid arthritis., PMID:38630712

Melan-A immunolabeling in canine extramedullary plasmacytomas., PMID:38642035

Flow cytometric analysis of immune cell populations in the bronchial and mesenteric lymph nodes of the dromedary camel., PMID:38746932

Deletion of Talin1 in Myeloid Cells Facilitates Atherosclerosis in Mice., PMID:38899470

CD47-SIRPα Blockade Sensitizes Head and Neck Squamous Cell Carcinoma to Cetuximab by Enhancing Macrophage Adhesion to Cancer Cells., PMID:38959336

Sarcomas of synovial origin in dogs: An updated review., PMID:39068516

Flow cytometric-based detection of CD80 is a useful diagnostic marker of acute myeloid leukemia in dogs., PMID:39224452

Targeting Human Pancreatic Cancer with a Fluorophore-Conjugated Mucin 4 (MUC4) Antibody: Initial Characterization in Orthotopic Cell Line Mouse Models., PMID:39458160

Mechanisms of Mt.b Ag85B-Fc fusion protein against allergic asthma in mice by intranasal immunization., PMID:39549815

Humanized anti-CD11d monoclonal antibodies suitable for basic research and therapeutic applications., PMID:39839909

Triple knockdown of CD11a, CD49d, and PSGL1 in T cells reduces CAR-T cell toxicity but preserves activity against solid tumors in mice., PMID:39841806

Dual in vivo T cell depleted haploidentical hematopoietic stem cell transplantation with post-transplant cyclophosphamide and anti-thymocyte globulin as a third salvage transplant for leukocyte adhesion deficiency with graft failure: a case report., PMID:39845947

Extracellular vesicle surface engineering with integrins (ITGAL & ITGB2) to specifically target ICAM-1-expressing endothelial cells., PMID:39885580

ICAM-1/CD18-mediated sequestration of parasitized phagocytes in cortical capillaries promotes neuronal colonization by Toxoplasma gondii., PMID:40229286

MOSPD2 regulates the activation state of αLβ2 integrin to control monocyte migration: applicability for treatment of chronic inflammatory diseases., PMID:40312574

Glycosylation-driven programs coordinate immunoregulatory and pro-angiogenic functions of myeloid-derived suppressor cells., PMID:40381622

PSGL-1 is a phagocytosis checkpoint that enables tumor escape from macrophage clearance., PMID:40512837

Datasheet
$ 198
Product specifications
50 T 198 100 T 328

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Anti-Human CD18/ITGB2 Antibody (60.3), FITC [FHC13141]
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