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Anti-Human TNFSF12/APO3L Antibody (SAA0806), FITC

Catalog #:   FHA69211 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1, kappa
Applications: ELISA, FCM
Accession: O43508
Overview

Catalog No.

FHA69211

Species reactivity

Human

Host species

Mouse

Isotype

IgG1, kappa

Clonality

Monoclonal

Conjugation

FITC

Target

TWEAK, DR3LG, TNFSF12, Tumor necrosis factor ligand superfamily member 12, APO3L, TNF-related weak inducer of apoptosis, APO3 ligand

Concentration

0.5 mg/ml

Endotoxin level

Please contact with the lab for this information.

Accession

O43508

Applications

ELISA, FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Stability and Storage

Store at 4°C for 12 months. Protect from light. Do not freeze.

Clone ID

SAA0806

Data Image
References

TWEAK increases angiogenesis to promote diabetic skin wound healing by regulating Fn14/EGFR signaling., PMID:39166480

Tweak/Fn14 system is involved in rhabdomyolysis-induced acute kidney injury., PMID:38007933

TNF-like weak inducer of apoptosis inhibition is comparable to IL-13 blockade in ameliorating atopic dermatitis inflammation., PMID:37650473

Artificial Neural Networks Predicted the Overall Survival and Molecular Subtypes of Diffuse Large B-Cell Lymphoma Using a Pancancer Immune-Oncology Panel., PMID:34945004

TWEAK functions with TNF and IL-17 on keratinocytes and is a potential target for psoriasis therapy., PMID:34797693

Interruption of neutrophil extracellular traps formation dictates host defense and tubular HOXA5 stability to augment efficacy of anti-Fn14 therapy against septic AKI., PMID:34646379

TWEAK Signaling Pathway Blockade Slows Cyst Growth and Disease Progression in Autosomal Dominant Polycystic Kidney Disease., PMID:34155062

Norcantharidin protects against renal interstitial fibrosis by suppressing TWEAK-mediated Smad3 phosphorylation., PMID:32979359

Serum and urine TNF-like weak inducer of apoptosis, monocyte chemoattractant protein-1 and neutrophil gelatinase-associated lipocalin as biomarkers of disease activity in patients with systemic lupus erythematosus., PMID:32041504

MicroRNA-889 Inhibits Autophagy To Maintain Mycobacterial Survival in Patients with Latent Tuberculosis Infection by Targeting TWEAK., PMID:31992621

Tumor Necrosis Factor (TNF) Receptor Expression Determines Keratinocyte Fate upon Stimulation with TNF-Like Weak Inducer of Apoptosis., PMID:31885495

The TNF-like weak inducer of the apoptosis/fibroblast growth factor-inducible molecule 14 axis mediates histamine and platelet-activating factor-induced subcutaneous vascular leakage and anaphylactic shock., PMID:31679818

Changes in serum TNF-like weak inducer of apoptosis (TWEAK) levels and Psoriasis Area Severity Index (PASI) scores in plaque psoriasis patients treated with conventional versus anti-TNF treatments., PMID:31531981

A major role of TWEAK/Fn14 axis as a therapeutic target for post-angioplasty restenosis., PMID:31395500

Tumor necrosis factor-like weak inducer of apoptosis induces inflammation in Graves' orbital fibroblasts., PMID:30576385

Combined utilization of untimed single urine of MCP-1 and TWEAK as a potential indicator for proteinuria in lupus nephritis: A case-control study., PMID:29668584

Effect of influenza vaccine on tumor necrosis factor-like weak inducer of apoptosis (TWEAK) in older adults., PMID:29548604

Enavatuzumab, a Humanized Anti-TWEAK Receptor Monoclonal Antibody, Exerts Antitumor Activity through Attracting and Activating Innate Immune Effector Cells., PMID:29075649

Predictive biological markers of systemic lupus erythematosus flares: a systematic literature review., PMID:29065901

TWEAK/Fn14 signaling in tumors., PMID:28639899

Role of the tumour necrosis factor-like weak inducer of apoptosis (TWEAK)/fibroblast growth factor-inducible 14 (Fn14) axis in autoimmune thyroid disease., PMID:28636775

Advanced glycation end products attenuate the function of tumor necrosis factor-like weak inducer of apoptosis to regulate the inflammatory response., PMID:28455790

TWEAK blockade decreases atherosclerotic lesion size and progression through suppression of STAT1 signaling in diabetic mice., PMID:28447667

Disruption of the TWEAK/Fn14 pathway prevents 5-fluorouracil-induced diarrhea in mice., PMID:28428709

Beyond TNF: TNF superfamily cytokines as targets for the treatment of rheumatic diseases., PMID:28275260

Systemic lupus erythematosus biomarkers: the challenging quest., PMID:28013203

Roles of tumour necrosis factor-related weak inducer of apoptosis/fibroblast growth factor-inducible 14 pathway in lupus nephritis., PMID:27786399

The role of soluble tumor necrosis factor like weak inducer of apoptosis and interleukin-17A in the etiopathogenesis of celiac disease: A cross-sectional study., PMID:27367991

Out of the TWEAKlight: Elucidating the Role of Fn14 and TWEAK in Acute Kidney Injury., PMID:27339384

TWEAK-binding autoantibodies are generated during psoriatic arthritis and are not influenced by anti-TNF therapy., PMID:27338143

Genes associated with common variable immunodeficiency: one diagnosis to rule them all?, PMID:27250108

Fn14-Fc suppresses germinal center formation and pathogenic B cells in a lupus mouse model via inhibition of the TWEAK/Fn14 Pathway., PMID:27098560

TWEAK-Fn14 Signaling Activates Myofibroblasts to Drive Progression of Fibrotic Kidney Disease., PMID:27026366

Population pharmacokinetic and pharmacodynamic analysis of BIIB023, an anti-TNF-like weak inducer of apoptosis (anti-TWEAK) monoclonal antibody., PMID:26896828

The role of circulating sTWEAK in the pathogenesis of Hashimoto's thyroiditis - a pilot study., PMID:26884302

The role of TWEAK/Fn14 signaling in the MPTP-model of Parkinson's disease., PMID:26808775

Towards new avenues in the management of lupus glomerulonephritis., PMID:26729459

The inflammatory cytokine TWEAK decreases PGC-1α expression and mitochondrial function in acute kidney injury., PMID:26535995

Exposure and Tumor Fn14 Expression as Determinants of Pharmacodynamics of the Anti-TWEAK Monoclonal Antibody RG7212 in Patients with Fn14-Positive Solid Tumors., PMID:26446946

Targeting of Fn14 Prevents Cancer-Induced Cachexia and Prolongs Survival., PMID:26359988

Blocking TWEAK-Fn14 interaction inhibits hematopoietic stem cell transplantation-induced intestinal cell death and reduces GVHD., PMID:26012567

TNF-like weak inducer of apoptosis promotes blood brain barrier disruption and increases neuronal cell death in MRL/lpr mice., PMID:25911200

Elevated Serum Levels of Soluble CD163 in Polymyositis and Dermatomyositis: Associated with Macrophage Infiltration in Muscle Tissue., PMID:25877505

Tweak regulates astrogliosis, microgliosis and skeletal muscle atrophy in a mouse model of amyotrophic lateral sclerosis., PMID:25765661

TWEAK and NT-proBNP levels predict exercise capacity in hypertrophic cardiomyopathy., PMID:25524713

TWEAK/Fn14, a pathway and novel therapeutic target in myotonic dystrophy., PMID:25504044

Deficiency of fibroblast growth factor-inducible 14 (Fn14) preserves the filtration barrier and ameliorates lupus nephritis., PMID:25270074

Pathological activation of canonical nuclear-factor κB by synergy of tumor necrosis factor α and TNF-like weak inducer of apoptosis in mouse acute colitis., PMID:25022957

TNF-like weak inducer of apoptosis aggravates left ventricular dysfunction after myocardial infarction in mice., PMID:24692845

TWEAK and the progression of renal disease: clinical translation., PMID:24493870

Datasheet
$ 225
Product specifications
50 T 225 100 T 372

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For research use only. Not for human or drug use.

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Anti-Human TNFSF12/APO3L Antibody (SAA0806), FITC [FHA69211]
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