Catalog No.
DHE41901
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Human
Isotype
TCR-scFv (ImmTAC)
Target
Cancer/testis antigen 1.4, MAGEA4, MAGE4, CT1.4, Melanoma-associated antigen 4, MAGE-X2 antigen, MAGE-41 antigen, MAGE-4 antigen, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P43358
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
Imc-C103C, Imc C103C, Imc C103C
Clone ID
Imc-C103C
Identification and validation of a novel autoantibody biomarker panel for differential diagnosis of pancreatic ductal adenocarcinoma., PMID:39949781
Adoptive T Cell Therapy Targeting MAGE-A4., PMID:39941782
MAGE-A4 pMHC-targeted CAR-T cells exploiting TCR machinery exhibit significantly improved in vivo function while retaining antigen specificity., PMID:39572159
Preclinical evaluation of a novel CAR-T therapy utilizing a scFv antibody highly specific to MAGE-A4p230-239/HLA-A∗02:01 complex., PMID:38243600
Diagnostic performance of anti-MAGEA family protein autoantibodies in esophageal squamous cell carcinoma., PMID:37866309
Involvement of NY-ESO-1 and MAGE-A4 in the pathogenesis of desmoid tumors., PMID:37266606
The development of a tumor-associated autoantibodies panel to predict clinical outcomes for immune checkpoint inhibitor-based treatment in patients with advanced non-small-cell lung cancer., PMID:36594104
Combinational expression of tumor testis antigens NY-ESO-1, MAGE-A3, and MAGE-A4 predicts response to immunotherapy in mucosal melanoma patients., PMID:36527482
Morphometric and immunohistochemical analysis as a method to identify undifferentiated spermatogonial cells in adult subjects with Klinefelter syndrome: a cohort study., PMID:36116982
Massive digital gene expression analysis reveals different predictive profiles for immune checkpoint inhibitor therapy between adenocarcinoma and squamous cell carcinoma of advanced lung cancer., PMID:35135489
Dynamic alterations of circulating T lymphocytes and the clinical response in patients with head and neck squamous cell carcinoma treated with nivolumab., PMID:34463793
Newly developed pseudogout arthritis after therapy with MAGE-A4 directed TCR T cells responded to treatment with tocilizumab., PMID:34233963
Autoantibody Signatures as a Biomarker Panel for the Detection of Nasopharyngeal Carcinoma., PMID:33653596
Antibody Responses to Cancer Antigens Identify Patients with a Poor Prognosis among HPV-Positive and HPV-Negative Head and Neck Squamous Cell Carcinoma Patients., PMID:31444248
The expression of melanoma-associated antigen A (MAGE-A) in oral squamous cell carcinoma: an evaluation of the significance for tumor prognosis., PMID:31093793
NY-ESO-1 antigen expression and immune response are associated with poor prognosis in MAGE-A4-vaccinated patients with esophageal or head/neck squamous cell carcinoma., PMID:30542513
Antibody response against cancer-testis antigens MAGEA4 and MAGEA10 in patients with melanoma., PMID:29928403
MAGE-A4 and MAGE-A1 Immunohistochemical Expression in High-grade Endometrial Cancer., PMID:29140883
[Expression of cancer testis (CT) antigens in pediatric and adolescent melanomas]., PMID:28631119
Correlation Between Expression of the Cancer/Testis Antigen KK-LC-1 and Helicobacter pylori Infection in Gastric Cancer., PMID:28438869
Promising immunotherapies for esophageal cancer., PMID:28366014
MAGE expression in head and neck squamous cell carcinoma primary tumors, lymph node metastases and respective recurrences-implications for immunotherapy., PMID:28146422
Time-dependent transition of the immunoglobulin G subclass and immunoglobulin E response in cancer patients vaccinated with cholesteryl pullulan-melanoma antigen gene-A4 nanogel., PMID:28105158
Case-Control Study: Smoking History Affects the Production of Tumor Antigen-Specific Antibodies NY-ESO-1 in Patients with Lung Cancer in Comparison with Cancer Disease-Free Group., PMID:27793776
Evaluation of the diagnostic value of 64 simultaneously measured autoantibodies for early detection of gastric cancer., PMID:27140836
Prospective evaluation of 64 serum autoantibodies as biomarkers for early detection of colorectal cancer in a true screening setting., PMID:26909861
Clinical relevance of antigen spreading pattern induced by CHP-MAGE-A4 cancer vaccination., PMID:26888315
Predictive and prognostic effect of CD133 and cancer-testis antigens in stage Ib-IIIA non-small cell lung cancer., PMID:26191258
Expansion and long-term culture of human spermatogonial stem cells via the activation of SMAD3 and AKT pathways., PMID:26088866
Adoptive immunotherapy of cancer utilizing genetically engineered lymphocytes., PMID:26041411
High expression of MAGE-A4 and MHC class I antigens in tumor cells and induction of MAGE-A4 immune responses are prognostic markers of CHP-MAGE-A4 cancer vaccine., PMID:25218300
Expression and immune responses to MAGE antigens predict survival in epithelial ovarian cancer., PMID:25101620
Clinical significance of immunohistochemical expression of cancer/testis tumor-associated antigens (MAGE-A1, MAGE-A3/4, NY-ESO-1) in patients with non-small cell lung cancer., PMID:24675493
Intratubular germ cell neoplasia of the human testis: heterogeneous protein expression and relation to invasive potential., PMID:24457464
The feasibility of fertility preservation in adolescents with Klinefelter syndrome., PMID:23539613
Expression of MAGE-C1/CT7 and selected cancer/testis antigens in ovarian borderline tumours and primary and recurrent ovarian carcinomas., PMID:23529156
[The regulation of antitumor immune responses by helper T cells--From the bench research to the discovery of H/K-HELP cancer vaccine]., PMID:23124083
Selfish spermatogonial selection: evidence from an immunohistochemical screen in testes of elderly men., PMID:22879958
Case report of apoptosis in testis of four AZFc-deleted patients: increased DNA fragmentation during meiosis, but decreased apoptotic markers in post-meiotic germ cells., PMID:22508792
Antigen-specificity of oligoclonal abnormal protein bands in multiple myeloma after allogeneic stem cell transplantation., PMID:22350072
First clinical trial of cancer vaccine therapy with artificially synthesized helper/ killer-hybrid epitope long peptide of MAGE-A4 cancer antigen., PMID:22221328
Ipilimumab increases activated T cells and enhances humoral immunity in patients with advanced melanoma., PMID:22130166
Expression of cancer-testis antigens MAGE-A4 and MAGE-C1 in oral squamous cell carcinoma., PMID:22083937
A novel double staining strategy for improved detection of testicular carcinoma in situ cells in human semen samples., PMID:21486421
Heteroclitic serological response in esophageal and prostate cancer patients after NY-ESO-1 protein vaccination., PMID:21413013
Expression of MAGE-A4 and MAGE-C1 tumor-associated antigen in benign and malignant thyroid diseases., PMID:21246638
Expression and prognostic significance of cancer-testis antigens (CTA) in intrahepatic cholagiocarcinoma., PMID:21211023
High expression of cancer testis antigens MAGE-A, MAGE-C1/CT7, MAGE-C2/CT10, NY-ESO-1, and gage in advanced squamous cell carcinoma of the larynx., PMID:20886663
Immunohistochemical expression of tumor antigens MAGE-A3/4 and NY-ESO-1 in renal oncocytoma and chromophobe renal cell carcinoma., PMID:20591578
Prognostic value of MAGE-A and NY-ESO-1 expression in pharyngeal cancer., PMID:20029985
For research use only. Not for human or drug use.
