Catalog No.
DHF71403
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Human
Isotype
IgG1-kappa
Target
DLK, DLK-1, pG2, DLK1, Protein delta homolog 1, FA1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P80370
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
LIV-1205, LIV1205, LIV 1205
Clone ID
LIV-1205
Bimodal genomic approach predicting Semaphorin 7A (SEMA7A) as prognostic biomarker in adrenocortical carcinoma., PMID:40291702
A Phase I, First-In-Human Study of CBA-1205, an Anti-DLK1 Monoclonal Antibody, in Patients With Advanced Solid Tumors., PMID:39832211
A Novel Glycoengineered Humanized Antibody Targeting DLK1 Exhibits Potent Anti-Tumor Activity in DLK1-Expressing Liver Cancer Cell Xenograft Models., PMID:39769389
A proteogenomic surfaceome study identifies DLK1 as an immunotherapeutic target in neuroblastoma., PMID:39454577
Identification of DLK1, a Notch ligand, as an immunotherapeutic target and regulator of tumor cell plasticity and chemoresistance in adrenocortical carcinoma., PMID:39416174
Brain ischemia causes systemic Notch1 activity in endothelial cells to drive atherosclerosis., PMID:39079536
DLK1 regulates periodontal inflammation by inhibiting NF-κB p65 and JNK signaling pathways., PMID:38995322
A proteogenomic surfaceome study identifies DLK1 as an immunotherapeutic target in neuroblastoma., PMID:38106022
Robust protein-based engineering of hepatocyte-like cells from human mesenchymal stem cells., PMID:36848084
Identification and Quantification of Proliferating Cells in Skeletal Muscle of Glutamine Supplemented Low- and Normal-Birth-Weight Piglets., PMID:36831247
DLK1-directed chimeric antigen receptor T-cell therapy for hepatocellular carcinoma., PMID:36002393
Aniridia-related keratopathy relevant cell signaling pathways in human fetal corneas., PMID:35551459
Delta-like 1-Expressing Cells at the Gland Base Promote Proliferation of Gastric Antral Stem Cells in Mouse., PMID:34438113
Development of antibodies against the notch ligand Delta-Like-1 by phage display with activity against breast cancer cells., PMID:33992842
Delta-like 1 homolog (DLK1) as a possible therapeutic target and its application to radioimmunotherapy using 125I-labelled anti-DLK1 antibody in lung cancer models (HOT1801 and FIGHT004)., PMID:33508526
Dermal Adipose Tissue Secretes HGF to Promote Human Hair Growth and Pigmentation., PMID:33493531
Functional characterization of DLK1/MEG3 locus on chromosome 14q32.2 reveals the differentiation of pituitary neuroendocrine tumors., PMID:33472171
CD28 Signaling Drives Notch Ligand Expression on CD4 T Cells., PMID:32457739
Heterogeneity of Satellite Cells Implicates DELTA1/NOTCH2 Signaling in Self-Renewal., PMID:32023464
In Vitro Conversion of Activated T Cells into Stem Cell Memory-Like T Cells., PMID:31396927
Retinal myeloid cells regulate tip cell selection and vascular branching morphogenesis via Notch ligand Delta-like 1., PMID:31278348
Delta-like 1 homologue promotes tumorigenesis and epithelial-mesenchymal transition of ovarian high-grade serous carcinoma through activation of Notch signaling., PMID:30626939
Altered Signaling Pathways in Aniridia-Related Keratopathy., PMID:30480741
Notch signaling mediated by Delta-like ligands 1 and 4 controls the pathogenesis of chronic GVHD in mice., PMID:30181175
Genome-wide meta-analysis identifies novel gender specific loci associated with thyroid antibodies level in Croatians., PMID:29678681
Antibody-based inhibition of circulating DLK1 protects from estrogen deficiency-induced bone loss in mice., PMID:29499415
Soluble delta-like 1 homolog (DLK1) stimulates angiogenesis through Notch1/Akt/eNOS signaling in endothelial cells., PMID:29383634
Production and characterization of a novel Delta-like 1 functional unit as a tool for Notch pathway activation and generation of a specific antibody., PMID:29366964
Overexpression of Notch ligand Delta-like-1 by dendritic cells enhances their immunoregulatory capacity and exerts antiallergic effects on Th2-mediated allergic asthma in mice., PMID:29038036
Both Notch1 and its ligands in B cells promote antibody production., PMID:28863329
A link between adipogenesis and innate immunity: RNase-L promotes 3T3-L1 adipogenesis by destabilizing Pref-1 mRNA., PMID:27831565
Notch signalling suppresses regulatory T-cell function in murine experimental autoimmune uveitis., PMID:27564686
A Role for DLK in Microtubule Reorganization to the Cell Periphery and in the Maintenance of Desmosomal and Tight Junction Integrity., PMID:27519653
Transient blockade of delta-like Notch ligands prevents allograft rejection mediated by cellular and humoral mechanisms in a mouse model of heart transplantation., PMID:25687759
Delta-like 1 homologue (DLK1) protein in neurons of the arcuate nucleus that control weight homeostasis and effect of fasting on hypothalamic DLK1 mRNA., PMID:25342302
Specific fibroblastic niches in secondary lymphoid organs orchestrate distinct Notch-regulated immune responses., PMID:25311507
Macrophage-derived delta-like protein 1 enhances interleukin-6 and matrix metalloproteinase 3 production by fibroblast-like synoviocytes in mice with collagen-induced arthritis., PMID:24943093
GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development., PMID:24929016
Identification of a human splenic marginal zone B cell precursor with NOTCH2-dependent differentiation properties., PMID:24733829
Mesenchymal progenitor cells in mouse foetal liver regulate differentiation and proliferation of hepatoblasts., PMID:24238062
Delta-like 1 homolog (dlk1): a marker for rhabdomyosarcomas implicated in skeletal muscle regeneration., PMID:23577150
Blockade of individual Notch ligands and receptors controls graft-versus-host disease., PMID:23454750
Methylation status of imprinted genes DLK1-GTL2, MEST (PEG1), ZAC (PLAGL1), and LINE-1 elements in spermatozoa of normozoospermic men, unlike H19 imprinting control regions, is not associated with idiopathic recurrent spontaneous miscarriages., PMID:23415968
Delta-like 1 homologue is a hypothalamus-enriched protein that is present in orexin-containing neurones of the lateral hypothalamic area., PMID:23387476
MicroRNA-34a is a tumor suppressor in choriocarcinoma via regulation of Delta-like1., PMID:23327670
A comparative analysis of the adipogenic potential in human mesenchymal stromal cells from cord blood and other sources., PMID:23260088
[Characterization of hepatic stem/progenitor cells by molecular markers]., PMID:23012873
Reprogramming IgH isotype-switched B cells to functional-grade induced pluripotent stem cells., PMID:22869756
hDlk-1: a cell surface marker common to normal hepatic stem/progenitor cells and carcinomas., PMID:22692292
Differential regulation of osteoclastogenesis by Notch2/Delta-like 1 and Notch1/Jagged1 axes., PMID:22390640
For research use only. Not for human or drug use.
