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Research Grade Anti-Human C1q Antibody (ANX005)

Catalog #:   DHC00201 Specific References (50) DATASHEET
Host species: Human
Isotype: IgG
Applications: Research Grade Biosimilar
Expression system: Mammalian Cells
Overview

Catalog No.

DHC00201

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

IgG

Target

C1QA, Complement C1q subcomponent subunit A

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P02745

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

ANX005, ANX 005, ANX-005

Clone ID

ANX005

Data Image
References

Microglial pruning of glycinergic synapses disinhibits spinal PKCγ interneurons to drive pain hypersensitivity in mice., PMID:40531965

CTRP7 as a molecular biomarker associating with responsiveness to pulmonary vasodilators: insights from human and animal studies in pulmonary arterial hypertension., PMID:40504501

Luminex-based pilot study identifies novel serum autoantibodies associated with disease activity in patients with lupus nephritis., PMID:40500568

A multicenter prospective cohort study evaluating impact of an active delisting strategy to enable kidney transplantation in wait-listed candidates with calculated Panel Reactive Antibody ≥ 99.9., PMID:40484353

Complement in anti-glomerular basement membrane glomerulonephritis., PMID:40469278

Evolving understanding of Guillain-Barré syndrome pathophysiology and the central role of the classical complement pathway in axonal injury., PMID:40438570

C1q Binds to CD4+ T Cells and Inhibits the Release of Pro-Inflammatory Cytokines: Role in the Pathogenesis of Systemic Lupus Erythematosus., PMID:40429614

A novel complement C1q A chain from marbled flounder, Pseudopleuronectes yokohamae: genome characterization, expression and potential role in antibacterial immunity., PMID:40349809

Bartonella Endocarditis-Associated Glomerulonephritis: A Mimicker of Autoimmunity and Vasculitis., PMID:40303199

Deposition of complement regulators on the surface of Plasmodium falciparum merozoites depends on the immune status of the host., PMID:40294075

Complement updates in optic neuritis., PMID:40206291

Direct immunofluorescence of labial gland in diagnosis of Sjögren's disease., PMID:40172814

C1q+ Macrophage-Tumor Cell Interaction Promoted Tumorigenesis via GPR17/PI3K/AKT Pathway Induced DNA Hypermethylation in Nasopharyngeal Carcinoma., PMID:40171991

Clinical and immunological biomarkers can identify proliferative changes and predict renal flares in lupus nephritis., PMID:40165257

IgM Variant of Proliferative Glomerulonephritis With Monoclonal Immunoglobulin Deposits: A Case Series., PMID:40147751

Anti-C1s autoantibodies as complementary serologic biomarker in lupus nephritis., PMID:40132784

Post-vaccination IgG4 and IgG2 class switch associates with increased risk of SARS-CoV-2 infections., PMID:40113142

ANCA Negative Vasculitis Manifesting as Pulmonary-Renal Syndrome in a Patient with Chronic Osteomyelitis., PMID:40087953

Evaluation of Serum CTRP-4 and CTRP-12 Levels in Hashimoto's Thyroiditis Patients: A Comparative Analysis with a Control Group and Their Correlation with Biochemical Factors., PMID:40060227

Intravitreal delivery of NMO-IgG causes primary retinal damage in the absence of optic nerve injury., PMID:40055743

Rare presentation of hypocomplementaemic urticarial vasculitis syndrome (HUVS) overlapping with systemic erythematosus lupus (SLE) and small lymphocytic lymphoma (SLL)., PMID:39933844

Two siblings with monogenic lupus due to C1qC deficiency and case based review., PMID:39843834

Non-canonical Roles of Complement in the CNS: From Synaptic Organizer to Presynaptic Modulator of Glutamate Transmission., PMID:39817397

Anti-C1q antibodies in IgG4-related disease are common and associated with renal involvement and cutaneous small-vessel vasculitis., PMID:39798124

Enhancing Neuron Activity Promotes Functional Recovery by Inhibiting Microglia-Mediated Synapse Elimination After Stroke., PMID:39772780

HLA and Non-HLA Factors for Donor Selection in Hematopoietic Stem Cell Transplantation with Post-Transplant Cyclophosphamide GvHD Prophylaxis., PMID:39768158

Enhancing complement activation by therapeutic anti-tumor antibodies: Mechanisms, strategies, and engineering approaches., PMID:39742715

A case of neuron-derived neurotrophic factor-positive, syphilis-related membranous nephropathy that achieved spontaneous remission., PMID:39733185

A novel monoclonal antibody against human thymic stromal lymphopoietin for the treatment of TSLP-mediated diseases., PMID:39726595

Exploring CTRP6: a biomarker and therapeutic target in metabolic diseases., PMID:39701154

Lupus nephritis and related renal disease: review from case series., PMID:39699701

Infiltrative classical monocyte-derived and SPP1 lipid-associated macrophages mediate inflammation and fibrosis in ANCA-associated glomerulonephritis., PMID:39694817

Immune complexome analysis reveals an autoimmune signature predictive of COVID-19 severity., PMID:39689808

Polyfunctionality and breadth of HIV-1 antibodies are associated with delayed disease progression., PMID:39661636

Characteristics of glomerulonephritis with dominant C1q precipitation compared to corresponding glomerulonephritis without C1q staining on immunofluorescent examination., PMID:39639420

A novel multiple marker microarray analyzer and methodology to predict major obstetric syndromes using surface markers of circulating extracellular vesicles from maternal plasma., PMID:39607297

A Case of Hypocomplementemic Urticarial Vasculitis Syndrome With Severe Renal and Gastrointestinal Involvement., PMID:39575061

Correlation of autoimmune response and immune system components in the progression of IgA nephropathy: A comparative study., PMID:39566436

Immune Markers and Inflammatory Cytokines in Granulomatous Lobular Mastitis: A Case-Control Study., PMID:39553312

Downhill running does not alter blood C1q availability or complement-dependent cytotoxicity of therapeutic monoclonal antibodies against haematological cancer cell lines in vitro., PMID:39548231

Beyond Recycling Antibodies: Crovalimab's Molecular Design Enables Four-Weekly Subcutaneous Injections for PNH Treatment., PMID:39519232

C1q Binding Ability for Prior Risk Assessment of Acute Antibody-Mediated Rejection in ABO-Incompatible Kidney Transplantation., PMID:39474587

Hematopoietic Stem Cell Transplantation for C1q Deficiency: A Study on Behalf of the EBMT Inborn Errors Working Party., PMID:39470951

Circulating Immune Complexes and Complement Activation in Sensitized Kidney Transplant Recipients., PMID:39456685

Immunoglobulin G and Complement as Major Players in the Neurodegeneration of Multiple Sclerosis., PMID:39456143

The evolution of flexibility and function in the Fc domains of IgM, IgY, and IgE., PMID:39445016

C1q-Fixing De Novo Donor Specific Antibodies in Therapeutic Management of Chronic Antibody-Mediated Rejection Postkidney Transplantation., PMID:39443200

Humoral signatures of Caspr2-antibody spectrum disorder track with clinical phenotypes and outcomes., PMID:39393351

Cardiac-derived CTRP9 mediates the protection of empagliflozin against diabetes-induced male subfertility in mice., PMID:39392219

Case Report: Hypocomplementemic urticarial vasculitis syndrome in a pediatric patient with complement factor 1 deficiency., PMID:39376673

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1486

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Research Grade Anti-Human C1q Antibody (ANX005) [DHC00201]
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