Catalog No.
YVV40301
Expression system
E. coli
Species
Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5)
Protein length
Gly387-Glu581
Predicted molecular weight
22.52 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P11818
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Fiber protein, SPIKE, Protein IV, L5
CELO Fiber1 Knob Is a Promising Candidate to Modify the Tropism of Adenoviral Vectors., PMID:36553583
Affilin-based retargeting of adenoviral vectors to the epidermal growth factor receptor., PMID:36442453
Hexon modification of human adenovirus type 5 vectors enables efficient transduction of human multipotent mesenchymal stromal cells., PMID:35402633
Immunoinformatic construction of an adenovirus-based modular vaccine platform and its application in the design of a SARS-CoV-2 vaccine., PMID:32758675
Whole genomic analysis of a potential recombinant human adenovirus type 1 in Qinghai plateau, China., PMID:32698808
Efficient gene transfer into T lymphocytes by fiber-modified human adenovirus 5., PMID:31014302
Interaction of Human Enterochromaffin Cells with Human Enteric Adenovirus 41 Leads to Serotonin Release and Subsequent Activation of Enteric Glia Cells., PMID:29367250
Defining a Novel Role for the Coxsackievirus and Adenovirus Receptor in Human Adenovirus Serotype 5 Transduction In Vitro in the Presence of Mouse Serum., PMID:28381574
Retargeting FX-binding-ablated HAdV-5 to vascular cells by inclusion of the RGD-4C peptide in hexon hypervariable region 7 and the HI loop., PMID:27189759
Differential immunogenicity between HAdV-5 and chimpanzee adenovirus vector ChAdOx1 is independent of fiber and penton RGD loop sequences in mice., PMID:26576856
Adenoviruses using the cancer marker EphA2 as a receptor in vitro and in vivo by genetic ligand insertion into different capsid scaffolds., PMID:24760010
An adenovirus vector incorporating carbohydrate binding domains utilizes glycans for gene transfer., PMID:23383334
Sstr2A: a relevant target for the delivery of genes into human glioblastoma cells using fiber-modified adenoviral vectors., PMID:22592599
Truncating the i-leader open reading frame enhances release of human adenovirus type 5 in glioma cells., PMID:21477385
Enhanced transduction of CAR-negative cells by protein IX-gene deleted adenovirus 5 vectors., PMID:21130482
An adenoviral vector expressing human adenovirus 5 and 3 fiber proteins for targeting heterogeneous cell populations., PMID:20828776
Influence of chimeric human-bovine fibers on adenoviral uptake by liver cells and the antiviral immune response., PMID:20393506
Chimeric adenoviral vectors incorporating a fiber of human adenovirus 3 efficiently mediate gene transfer into prostate cancer cells., PMID:19902467
Packaging of viral RNAs in virions of adenoviruses., PMID:19196470
Three-dimensional structure of canine adenovirus serotype 2 capsid., PMID:18216088
A system for efficient generation of adenovirus protein IX-producing helper cell lines., PMID:16288495
Detection of antibodies against adenovirus protein IX, fiber, and hexon in human sera by immunoblot assay., PMID:16145087