Catalog No.
RHJ04002
Species reactivity
Human
Host species
Alpaca
Isotype
VHH-6His
Clonality
Monoclonal
Target
CD276, B7-H3, Costimulatory molecule, B7H3, 4Ig-B7-H3, B7 homolog 3, CD276 antigen
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q5ZPR3
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA2193
B7-H3 in glioblastoma and beyond: significance and therapeutic strategies., PMID:39664380
Preclinical evaluation of antigen-sensitive B7-H3-targeting nanobody-based CAR-T cells in glioblastoma cautions for on-target, off-tumor toxicity., PMID:39562005
B7-H3-Targeting Chimeric Antigen Receptors Epstein-Barr Virus-specific T Cells Provides a Tumor Agnostic Off-The-Shelf Therapy Against B7-H3-positive Solid Tumors., PMID:38717140
CD276-CAR T cells and Dual-CAR T cells targeting CD276/FGFR4 promote rhabdomyosarcoma clearance in orthotopic mouse models., PMID:37924157
Camel nanobody-based B7-H3 CAR-T cells show high efficacy against large solid tumours., PMID:37739951
Advances in immunotherapeutic targets for childhood cancers: A focus on glypican-2 and B7-H3., PMID:33992682
Advanced genetic engineering to achieve in vivo targeting of adenovirus utilizing camelid single domain antibody., PMID:33872627
Isolation of rabbit single domain antibodies to B7-H3 via protein immunization and phage display., PMID:32166218
For research use only. Not for human or drug use.
