Catalog No.
DHE75503
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Human
Isotype
IgG
Clonality
Monoclonal
Target
MT-MMP 1, Matrix metalloproteinase-14, Membrane-type matrix metalloproteinase 1, Membrane-type-1 matrix metalloproteinase, MMP14, MTMMP1, MT1-MMP, MMP-14, MMP-X1, MT1MMP
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P50281
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
RLVT 14-02, RLVT-14-02, RLVT14-02
Clone ID
RLVT 14-02
Cytokine CCL9 Mediates Oncogenic KRAS-Induced Pancreatic Acinar-to-Ductal Metaplasia by Promoting Reactive Oxygen Species and Metalloproteinases., PMID:38731942
The interplay of Cxcl10+/Mmp14+ monocytes and Ccl3+ neutrophils proactively mediates silica-induced pulmonary fibrosis., PMID:38335607
Genetically engineered nano-melittin vesicles for multimodal synergetic cancer therapy., PMID:38023709
Substrate derived sequences act as subsite-blocking motifs in protease inhibitory antibodies., PMID:37278099
MMP14 is a diagnostic gene of intrahepatic cholangiocarcinoma associated with immune cell infiltration., PMID:37274806
Bone sialoprotein promotes lung cancer osteolytic bone metastasis via MMP14-dependent mechanisms., PMID:37028462
Atorvastatin attenuates NS1 (Non-structural protein-1) of dengue type-2 serotype-induced expressions of matrix metalloproteinases in HL-60 cells, differentiated to neutrophils: Implications for the immunopathogenesis of dengue viral disease., PMID:36108401
Endoglin and MMP14 Contribute to Ewing Sarcoma Spreading by Modulation of Cell-Matrix Interactions., PMID:35955799
Matrix Metalloproteinases Expression Is Associated with SARS-CoV-2-Induced Lung Pathology and Extracellular-Matrix Remodeling in K18-hACE2 Mice., PMID:35893698
Selfish antibodies target auto-antigens in cancer., PMID:35658013
Breaching B cell tolerance in the tumor microenvironment., PMID:35413269
Locally produced autoantibodies in cancer., PMID:35364029
Tumor-reactive antibodies evolve from non-binding and autoreactive precursors., PMID:35305314
Modulation of the Physical Properties of 3D Spheroids Derived from Human Scleral Stroma Fibroblasts (HSSFs) with Different Axial Lengths Obtained from Surgical Patients., PMID:34698138
Extracellular matrix remodeling and inflammatory pathway in human endometrium: insights from uterine leiomyomas., PMID:34256950
Inhibition of β1 integrin induces its association with MT1-MMP and decreases MT1-MMP internalization and cellular invasiveness., PMID:33744418
Hematopoietic stem cell gene therapy targeting TGFβ enhances the efficacy of irradiation therapy in a preclinical glioblastoma model., PMID:33707311
Matrix metalloproteinases and their inhibitors in Fuchs endothelial corneal dystrophy., PMID:33617849
Expression of invadopodia markers can identify oral lesions with a high risk of malignant transformation., PMID:33001588
Protease Inhibition Mechanism of Camelid-like Synthetic Human Antibodies., PMID:32997500
LOXL2 Inhibition Paves the Way for Macrophage-Mediated Collagen Degradation in Liver Fibrosis., PMID:32296422
β1 integrin-mediated signaling regulates MT1-MMP phosphorylation to promote tumor cell invasion., PMID:32205364
Antiangiogenic immunotherapy suppresses desmoplastic and chemoresistant intestinal tumors in mice., PMID:32015230
Morphological and Molecular Changes in Juvenile Normal Human Fibroblasts Exposed to Simulated Microgravity., PMID:31417174
Functional selection of protease inhibitory antibodies., PMID:31363054
Inflammatory Bowel Disease Types Differ in Markers of Inflammation, Gut Barrier and in Specific Anti-Bacterial Response., PMID:31337064
Inhibitory Antibodies Designed for Matrix Metalloproteinase Modulation., PMID:31216704
CAIX Regulates Invadopodia Formation through Both a pH-Dependent Mechanism and Interplay with Actin Regulatory Proteins., PMID:31167468
MMP14-Containing Exosomes Cleave VEGFR1 and Promote VEGFA-Induced Migration and Proliferation of Vascular Endothelial Cells., PMID:31117124
[Not Available]., PMID:31082464
AID modulates carcinogenesis network via DNA demethylation in bladder urothelial cell carcinoma., PMID:30874539
Myosin-X Silencing in the Trabecular Meshwork Suggests a Role for Tunneling Nanotubes in Outflow Regulation., PMID:30807639
Reducing proteolytic liability of a MMP-14 inhibitory antibody by site-saturation mutagenesis., PMID:30592555
Preclinical Efficacy of Endoglin-Targeting Antibody-Drug Conjugates for the Treatment of Ewing Sarcoma., PMID:30420447
Selectivity Conversion of Protease Inhibitory Antibodies., PMID:30406213
Epitope-specific affinity maturation improved stability of potent protease inhibitory antibodies., PMID:30102763
Use of a novel camelid-inspired human antibody demonstrates the importance of MMP-14 to cancer stem cell function in the metastatic process., PMID:30034628
MMP14 is a novel target of PTH signaling in osteocytes that controls resorption by regulating soluble RANKL production., PMID:29401593
Generation of Highly Selective MMP Antibody Inhibitors., PMID:29318563
A novel immunotherapy targeting MMP-14 limits hypoxia, immune suppression and metastasis in triple-negative breast cancer models., PMID:28938563
Prognostic Influence of Tumor Stroma on Breast Cancer Subtypes., PMID:28927692
PAR-1 and PAR-2 Expression Is Enhanced in Inflamed Odontoblast Cells., PMID:28759300
Cadherin composition and multicellular aggregate invasion in organotypic models of epithelial ovarian cancer intraperitoneal metastasis., PMID:28628116
Effects of C-reactive protein on the expression of matrix metalloproteinases and their inhibitors via Fcγ receptors on 3T3-L1 adipocytes., PMID:28539825
Modulation of Matrix Metalloproteinase 14, Tissue Inhibitor of Metalloproteinase 3, Tissue Inhibitor of Metalloproteinase 4, and Inducible Nitric Oxide Synthase in the Development of Periapical Lesions., PMID:28527839
Efficient Antibody Assembly in E. coli Periplasm by Disulfide Bond Folding Factor Co-expression and Culture Optimization., PMID:28488120
Clinically compatible flexible wide-field multi-color fluorescence endoscopy with a porcine colon model., PMID:28270983
Inhibition of Shedding of Low-Density Lipoprotein Receptor-Related Protein 1 Reverses Cartilage Matrix Degradation in Osteoarthritis., PMID:28235248
MMP-2 and MMP-14 Silencing Inhibits VEGFR2 Cleavage and Induces the Differentiation of Porcine Adipose-Derived Mesenchymal Stem Cells to Endothelial Cells., PMID:28213979
Identification of highly selective MMP-14 inhibitory Fabs by deep sequencing., PMID:28090632
For research use only. Not for human or drug use.
