Catalog No.
YVV05901
Expression system
E. coli
Species
African swine fever virus (ASFV)
Protein length
Ser230-Ile360
Predicted molecular weight
17.11 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
A0A0A7W5A6
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 5% Trehalose, 2% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CD2 homolog, 5HL, CD2v, T-lymphocyte CD2 receptor-like protein, pEP402R, EP402R, EP402R CDS, ASFV-Georgia_4-082, ASFV_Kyiv_2016_131_00086
Note
For research use only.
Recombinant vaccinia vectored ASFV vaccine enhances swine survival against genotype II challenge. [YVV05901]
Deletion of a CD2-like gene, 8-DR, from African swine fever virus affects viral infection in domestic swine., PMID:9525608
The CD2v protein enhances African swine fever virus replication in the tick vector, Ornithodoros erraticus., PMID:19729182
African swine fever virus serotype-specific proteins are significant protective antigens for African swine fever., PMID:27114233
Improved Strategy for Molecular Characterization of African Swine Fever Viruses from Sardinia, Based on Analysis of p30, CD2V and I73R/I329L Variable Regions., PMID:27174805
Evolution of African swine fever virus genes related to evasion of host immune response., PMID:27599940
Safety and immunogenicity of mammalian cell derived and Modified Vaccinia Ankara vectored African swine fever subunit antigens in swine., PMID:28241999
BA71ΔCD2: a New Recombinant Live Attenuated African Swine Fever Virus with Cross-Protective Capabilities., PMID:28814514
[ASF virus replication features in the presence of recombinant proteins CD2v, pX69R and pE248R.]., PMID:32163686
Identification of T-cell epitopes in African swine fever virus CD2v and C-type lectin proteins., PMID:30628881
Interaction of historical and modern Sardinian African swine fever viruses with porcine and wild-boar monocytes and monocyte-derived macrophages., PMID:30631959
An Update on African Swine Fever Virology., PMID:31533244
Deletion of CD2-like gene from the genome of African swine fever virus strain Georgia does not attenuate virulence in swine., PMID:31949276
Production of Recombinant African Swine Fever Viruses: Speeding Up the Process., PMID:32516890
Deletion of CD2-Like (CD2v) and C-Type Lectin-Like (EP153R) Genes from African Swine Fever Virus Georgia-∆9GL Abrogates Its Effectiveness as an Experimental Vaccine., PMID:33092057
Recombination shapes African swine fever virus serotype-specific locus evolution., PMID:33116230
The first complete genome sequence of the African swine fever virus genotype X and serogroup 7 isolated in domestic pigs from the Democratic Republic of Congo., PMID:33478547
The genetic variation landscape of African swine fever virus reveals frequent positive selection and adaptive flexibility., PMID:33751854
Identification of a new cell-penetrating peptide derived from the african swine fever virus CD2v protein., PMID:34006158
Growth Kinetics and Protective Efficacy of Attenuated ASFV Strain Congo with Deletion of the EP402 Gene., PMID:34203302
African Swine Fever Virus CD2v Protein Induces β-Interferon Expression and Apoptosis in Swine Peripheral Blood Mononuclear Cells., PMID:34452346
Role of African Swine Fever Virus Proteins EP153R and EP402R in Reducing Viral Persistence in Blood and Virulence in Pigs Infected with BeninΔDP148R., PMID:34643433
Genetic Characterization and Variation of African Swine Fever Virus China/GD/2019 Strain in Domestic Pigs., PMID:35056045
Live pig markets are hotspots for spread of African swine fever virus in Nigeria., PMID:35179830
Genetic variation and evolution of attenuated African swine fever virus strain isolated in the field: A review., PMID:35872281
First Report of a Complete Genome Sequence of a Variant African Swine Fever Virus in the Mekong Delta, Vietnam., PMID:35890041
Co-Deletion of A238L and EP402R Genes from a Genotype IX African Swine Fever Virus Results in Partial Attenuation and Protection in Swine., PMID:36146830
Expression of extracellular domain of ASFV CD2v protein in mammalian cells and identification of B cell epitopes., PMID:36356676
Molecular Characterization of African Swine Fever Viruses Circulating in Can Tho City, Vietnam., PMID:36779206
African Swine Fever Virus HLJ/18 CD2v Suppresses Type I IFN Production and IFN-Stimulated Genes Expression through Negatively Regulating cGMP-AMP Synthase-STING and IFN Signaling Pathways., PMID:36971697
Subsequent Immunization of Pigs with African Swine Fever Virus (ASFV) Seroimmunotype IV Vaccine Strain FK-32/135 and by Recombinant Plasmid DNA Containing the CD2v Derived from MK-200 ASFV Seroimmunotype III Strain Does Not Protect from Challenge with ASFV Seroimmunotype III., PMID:37243111
Highly lethal genotype I and II recombinant African swine fever viruses detected in pigs., PMID:37248233
Deletion of the CD2 Gene in the Virulent ASFV Congo Strain Affects Viremia in Domestic Swine, but Not the Virulence., PMID:37370512
A new vaccination regimen using adenovirus-vectored vaccine confers effective protection against African swine fever virus in swine., PMID:37401832
A quadruple fluorescence quantitative PCR method for the identification of wild strains of african swine fever and gene-deficient strains., PMID:37452402
Mucosal and cellular immune responses elicited by nasal and intramuscular inoculation with ASFV candidate immunogens., PMID:37720232
Deletion of the EP402R Gene from the Genome of African Swine Fever Vaccine Strain ASFV-G-∆I177L Provides the Potential Capability of Differentiating between Infected and Vaccinated Animals., PMID:38543742
Nanobodies against African swine fever virus p72 and CD2v proteins as reagents for developing two cELISAs to detect viral antibodies., PMID:38588947
Saccharomyces cerevisiae oral immunization in mice using multi-antigen of the African swine fever virus elicits a robust immune response., PMID:38742108
From structure prediction to function: defining the domain on the African swine fever virus CD2v protein required for binding to erythrocytes., PMID:39688401
For research use only. Not for human or drug use.
