Catalog No.
PMG76001
Species reactivity
Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Mouse IL27B/EBI3 (Thr20-Pro228).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Interleukin-27 subunit beta, IL-27 subunit beta, IL-27B, Epstein-Barr virus-induced gene 3 protein homolog, Ebi3, Il27b
Purification
Purified by antigen affinity column.
Accession
O35228
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Multifaceted Analysis of IL-23A- and/or EBI3-Including Cytokines Produced by Psoriatic Keratinocytes., PMID:34884474
Mycobacterium tuberculosis (MTB) antigen-induced upregulation of interleukin-35 expression in patients with MTB infection: In vitro blockade of the effects of interleukin-35 on T lymphocyte subsets., PMID:34245560
Plasmacytoid dendritic cells protect against immune-mediated acute liver injury via IL-35., PMID:31264967
Increased expression of the immunosuppressive interleukin-35 in patients with non-small cell lung cancer., PMID:30956278
Aberrant IL-35 levels in patients with primary Sjogren's syndrome., PMID:30589451
Decreased Gene Expression of Epstein-Barr Virus-Induced Gene 3 (EBI-3) may Contribute to the Pathogenesis of Rheumatoid Arthritis., PMID:30513021
Interleukin 35 Expression Correlates With Microvessel Density in Pancreatic Ductal Adenocarcinoma, Recruits Monocytes, and Promotes Growth and Angiogenesis of Xenograft Tumors in Mice., PMID:28989066
Increased interleukin-27 cytokine expression in the central nervous system of multiple sclerosis patients., PMID:28738904
Soluble serum VCAM-1, whole blood mRNA expression and treatment response in natalizumab-treated multiple sclerosis., PMID:27919501
Elevated level of interleukin-35 in colorectal cancer induces conversion of T cells into iTr35 by activating STAT1/STAT3., PMID:27682874
Overexpression of Epstein-Barr virus-induced gene 3 protein (EBI3) in MRL/lpr mice suppresses their lupus nephritis by activating regulatory T cells., PMID:23845089
Distinct subunit pairing criteria within the heterodimeric IL-12 cytokine family., PMID:22487722
The calcineurin inhibitor tacrolimus allows the induction of functional CD4CD25 regulatory T cells by rabbit anti-thymocyte globulins., PMID:20528886
IL-35 is a novel cytokine with therapeutic effects against collagen-induced arthritis through the expansion of regulatory T cells and suppression of Th17 cells., PMID:17874423
Expression of IL-27 in human Th1-associated granulomatous diseases., PMID:14743498
Expression of Epstein-Barr virus-induced gene 3, an interleukin-12 p40-related molecule, throughout human pregnancy: involvement of syncytiotrophoblasts and extravillous trophoblasts., PMID:11696437
An interleukin 12-related cytokine is up-regulated in ulcerative colitis but not in Crohn's disease., PMID:9679036
For research use only. Not for human or drug use.
