Catalog No.
PMF71901
Species reactivity
Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Mouse HAMP/Hepcidin (Thr24-Thr83).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Hepcidin, Hamp, Hamp1, Hepc, Hepc1
Purification
Purified by antigen affinity column.
Accession
Q9EQ21
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Synthetic Antimicrobial Peptides Fail to Induce Leucocyte Innate Immune Functions but Elicit Opposing Transcriptomic Profiles in European Sea Bass and Gilthead Seabream., PMID:38393057
Bone marrow stromal cell-derived hepcidin has antimicrobial and immunomodulatory activities., PMID:38368463
Dupilumab-Associated Sezary Syndrome., PMID:37822402
Myeloid cell iron uptake pathways and paramagnetic rim formation in multiple sclerosis., PMID:37715818
Dupilumab-associated mycosis fungoides: a cross-sectional study., PMID:37270763
Epstein-Barr Virus Infection Is Associated with Elevated Hepcidin Levels., PMID:36675141
Selective CNS Targeting and Distribution with a Refined Region-Specific Intranasal Delivery Technique via the Olfactory Mucosa., PMID:34834319
From the Cochrane Library: Systemic Treatments for Metastatic Cutaneous Melanoma., PMID:37632820
Immunoadsorption for heart failure is associated with normalization of iron metabolism., PMID:33843393
Atypical juvenile hereditary hemochromatosis onset with positive pancreatic islet autoantibodies diabetes caused by novel mutations in HAMP and overall clinical management., PMID:33016646
Novel Insights Into the Effects of Interleukin 6 Antagonism in Non-ST-Segment-Elevation Myocardial Infarction Employing the SOMAscan Proteomics Platform., PMID:32515246
Evidence for dimerization of ferroportin in a human hepatic cell line using proximity ligation assays., PMID:32301493
Targeting the hepcidin-ferroportin pathway in anaemia of chronic kidney disease., PMID:30677788
Hepcidin mediated iron homoeostasis as immune regulator in visceral leishmaniasis patients., PMID:30402883
The Hepcidin/Ferroportin axis modulates proliferation of pulmonary artery smooth muscle cells., PMID:30154413
β-Defensin 1 Is Prominent in the Liver and Induced During Cholestasis by Bilirubin and Bile Acids via Farnesoid X Receptor and Constitutive Androstane Receptor., PMID:30100908
The dynamics of hepcidin-ferroportin internalization and consequences of a novel ferroportin disease mutation., PMID:28681497
Erythropoietin administration increases splenic erythroferrone protein content and liver TMPRSS6 protein content in rats., PMID:28282554
Two routes of infection with Photobacterium damselae subsp. piscicida are effective in the modulation of the transcription of immune related genes in Solea senegalensis., PMID:27590420
Disruption of Iron Regulation after Radiation and Donor Cell Infusion., PMID:27060441
Increased hepcidin in transferrin-treated thalassemic mice correlates with increased liver BMP2 expression and decreased hepatocyte ERK activation., PMID:26635037
Expression and cellular localization of hepcidin mRNA and protein in normal rat brain., PMID:25896789
RAP-011, an activin receptor ligand trap, increases hemoglobin concentration in hepcidin transgenic mice., PMID:25236856
Apoptosis induced by Fas signaling does not alter hepatic hepcidin expression., PMID:25225605
Quercetin prevents ethanol-induced iron overload by regulating hepcidin through the BMP6/SMAD4 signaling pathway., PMID:24746831
Hepcidin plays a negative role in liver regeneration., PMID:24123375
[Hemochromatosis: one form of iron-overload diseases]., PMID:23853349
IL-22 regulates iron availability in vivo through the induction of hepcidin., PMID:23836059
Allogeneic transplantation, Fas signaling, and dysregulation of hepcidin., PMID:23707854
Effects of subcutaneous and intravenous golimumab on inflammatory biomarkers in patients with rheumatoid arthritis: results of a phase 1, randomized, open-label trial., PMID:23418046
Increased hepcidin expression in multibacillary leprosy., PMID:23283470
Inflammation-induced hepcidin is associated with the development of anemia and coronary artery lesions in Kawasaki disease., PMID:22392047
Targeting the hepcidin-ferroportin axis to develop new treatment strategies for anemia of chronic disease and anemia of inflammation., PMID:22290531
[The effects and mechanisms of erythropoietin on hepcidin of human monocytes]., PMID:22213867
Hepatic hypoxia-inducible factor-2 down-regulates hepcidin expression in mice through an erythropoietin-mediated increase in erythropoiesis., PMID:22207682
Recombinant medaka (Oryzias melastigmus) pro-hepcidin: Multifunctional characterization., PMID:22051539
Effects of a single dose of oral iron on hepcidin concentrations in human urine and serum analyzed by a robust LC-MS/MS method., PMID:21867695
Hepcidin is localised in gastric parietal cells, regulates acid secretion and is induced by Helicobacter pylori infection., PMID:21757452
Insights into the antibacterial and immunomodulatory functions of tilapia hepcidin (TH)2-3 against Vibrio vulnificus infection in mice., PMID:21756935
Pharmacologic inhibition of hepcidin expression reverses anemia of chronic inflammation in rats., PMID:21730356
Modulation of the immune-related gene responses to protect mice against Japanese encephalitis virus using the antimicrobial peptide, tilapia hepcidin 1-5., PMID:21726898
Nuclear factor-κB mediated lipopolysaccharide-induced mRNA expression of hepcidin in human peripheral blood leukocytes., PMID:21685415
Regulation of TMPRSS6 by BMP6 and iron in human cells and mice., PMID:21622652
[Effect of recombinant human erythropoietin on hepcidin mRNA expression in patients with multiple myeloma]., PMID:21518494
Case report: branch retinal vein occlusion and primary antiphospholipid syndrome., PMID:21511536
The bone morphogenetic protein-hepcidin axis as a therapeutic target in inflammatory bowel disease., PMID:21351217
Hepcidin and iron species distribution inside the first-trimester human gestational sac., PMID:21177636
A novel monoclonal antibody immunoassay for the detection of human serum hepcidin., PMID:21136275
Iron overload induces BMP6 expression in the liver but not in the duodenum., PMID:20952515
Hepcidin in human iron disorders: therapeutic implications., PMID:20932599