Catalog No.
PMF70301
Species reactivity
Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Mouse CCL8/MCP-2 (Gly24-Pro97).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
C-C motif chemokine 8, Monocyte chemoattractant protein 2, Monocyte chemotactic protein 2, MCP-2, Small-inducible cytokine A8, Ccl8, Mcp2, Scya8
Purification
Purified by antigen affinity column.
Accession
Q9Z121
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
A biomathematical model of SARS-CoV-2 in Syrian hamsters., PMID:39695178
Multiarray screening identifies plasma proteins associated with Th17 cell differentiation and viral defense in coincident asthma and obesity., PMID:38967090
Spatial characterization of interface dermatitis in cutaneous lupus reveals novel chemokine ligand-receptor pairs that drive disease., PMID:38260617
Analysis of Changes in Plasma Cytokine Levels in Response to IL12 Therapy in Three Clinical Trials., PMID:38108458
Serum profiling identifies CCL8, CXCL13, and IL-1RA as markers of active disease in patients with systemic lupus erythematosus., PMID:38098483
Identification of small compounds that inhibit multiple myeloma proliferation by targeting c-Maf transcriptional activity., PMID:37879249
Different mechanisms of CD200-CD200R induce diverse outcomes in cancer treatment., PMID:37734537
Mesenchymal stem cells enhance CCL8 expression by podocytes in lupus-prone MRL.Faslpr mice., PMID:37567910
Effects of leptin on the viability of human ovarian cancer cells and changes in cytokine expression levels., PMID:37155466
Alteration of the tumor microenvironment by pharmacological inhibition of EZH2 in hepatocellular carcinoma., PMID:37001386
Inflammatory chemokine (C-C motif) ligand 8 inhibition ameliorates peritoneal fibrosis., PMID:36468785
Beneficial effects of CCL8 inhibition at lipopolysaccharide-induced lung injury., PMID:36404927
Analysis of gene expression profiles to study malaria vaccine dose efficacy and immune response modulation., PMID:36239109
Circulating inflammatory proteins associate with response to immune checkpoint inhibition therapy in patients with advanced melanoma., PMID:36007304
Chemokine (C-C Motif) Ligand 8 and Tubulo-Interstitial Injury in Chronic Kidney Disease., PMID:35203308
Combined adjuvant effects of ambient vapor-phase organic components and particulate matter potently promote allergic sensitization and Th2-skewing cytokine and chemokine milieux in mice: The importance of mechanistic multi-pollutant research., PMID:34863859
Pathogenic roles and therapeutic potential of the CCL8-CCR8 axis in a murine model of IgG4-related sialadenitis., PMID:34391459
CCL8 mediates crosstalk between endothelial colony forming cells and triple-negative breast cancer cells through IL-8, aggravating invasion and tumorigenicity., PMID:33833397
C-C motif ligand 8 promotes atherosclerosis via NADPH oxidase 2/reactive oxygen species-induced endothelial permeability increase., PMID:33741452
Airway macrophage-intrinsic TGF-β1 regulates pulmonary immunity during early-life allergen exposure., PMID:33571538
Nuclear IL-33 restrains the early conversion of fibroblasts to an extracellular matrix-secreting phenotype., PMID:33420328
Cytokines/Chemokines: Potential Biomarkers for Non-paraneoplastic Anti-N-Methyl-D-Aspartate Receptor Encephalitis., PMID:33408682
Longitudinal proteomic profiling reveals increased early inflammation and sustained apoptosis proteins in severe COVID-19., PMID:33239683
Asymptomatic Infection of Marburg Virus Reservoir Bats Is Explained by a Strategy of Immunoprotective Disease Tolerance., PMID:33157026
IL6/sIL6R regulates TNFα-inflammatory response in synovial fibroblasts through modulation of transcriptional and post-transcriptional mechanisms., PMID:33126846
Targeting Chemokines and Chemokine Receptors in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis., PMID:33061527
CCL8 Promotes Postpartum Breast Cancer by Recruiting M2 Macrophages., PMID:32535027
CaSR Antagonist (Calcilytic) NPS 2143 Hinders the Release of Neuroinflammatory IL-6, Soluble ICAM-1, RANTES, and MCP-2 from Aβ-Exposed Human Cortical Astrocytes., PMID:32498476
CCL8 secreted by tumor-associated macrophages promotes invasion and stemness of glioblastoma cells via ERK1/2 signaling., PMID:31748682
Hypoxia-induced ZEB1 promotes cervical cancer progression via CCL8-dependent tumour-associated macrophage recruitment., PMID:31263103
Monitoring of Protein Biomarkers of Inflammation in Human Traumatic Brain Injury Using Microdialysis and Proximity Extension Assay Technology in Neurointensive Care., PMID:31017044
Cytokines and chemokines expression in serum of patients with neuromyelitis optica., PMID:30718956
Pleurotus citrinopileatus polysaccharide stimulates anti-inflammatory properties during monocyte-to-macrophage differentiation., PMID:30392853
MicroRNA-146a-5p attenuates visceral hypersensitivity through targeting chemokine CCL8 in the spinal cord in a mouse model of colitis., PMID:29550454
Murine chronic graft-versus-host disease proteome profiling discovers CCL15 as a novel biomarker in patients., PMID:29348127
Direct biological effects of fractional ultrapulsed CO2 laser irradiation on keratinocytes and fibroblasts in human organotypic full-thickness 3D skin models., PMID:29218493
Transcriptome analysis of plasmid-induced genes sheds light on the role of type I IFN as adjuvant in DNA vaccine against infectious salmon anemia virus., PMID:29161315
Chemokine CCL8 and its receptor CCR5 in the spinal cord are involved in visceral pain induced by experimental colitis in mice., PMID:29037608
CXCL9, a promising biomarker in the diagnosis of chronic Q fever., PMID:28793883
Pleurotus citrinopileatus polysaccharide induces activation of human dendritic cells through multiple pathways., PMID:27592080
Therapeutic implication of genetic variants of IL13 and STAT4 in airway remodelling with bronchial asthma., PMID:26765219
Intestinal CD169(+) macrophages initiate mucosal inflammation by secreting CCL8 that recruits inflammatory monocytes., PMID:26193821
The prognostic significance of PD-L1 in bladder cancer., PMID:25963805
Blockade of vascular endothelial growth factor receptor 1 prevents inflammation and vascular leakage in diabetic retinopathy., PMID:25821590
CC Chemokine Ligand 18 in ANCA-Associated Crescentic GN., PMID:25762060
Inflammatory molecular signature associated with infectious agents in psychosis., PMID:24743863
Peripheral blood mononuclear cells derived from grand multigravidae display a distinct cytokine profile in response to P. falciparum infected erythrocytes., PMID:24465935
Dectin-2 regulates the effector phase of house dust mite-elicited pulmonary inflammation independently from its role in sensitization., PMID:24453247
Characterization of regulatory dendritic cells differentiated from the bone marrow of UV-irradiated mice., PMID:23826713
Chemokine expression in retinal pigment epithelial ARPE-19 cells in response to coculture with activated T cells., PMID:23150618
For research use only. Not for human or drug use.
