Catalog No.
PMF16401
Species reactivity
Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Mouse TCL1A (Met1-Glu116).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
T-cell leukemia/lymphoma protein 1A, Oncogene TCL-1, Oncogene TCL1, Protein p14 TCL1, Tcl1a, Tcl1
Purification
Purified by antigen affinity column.
Accession
P56280
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Single-cell transcriptomics reveals the immune mechanisms by which tonsillectomy improves clinical outcomes of recurrent Immuoglobulin A nephropathy after kidney transplant., PMID:39985963
Evaluation of non-invasive biomarkers of kidney allograft rejection in a prospective multicenter unselected cohort study (EU-TRAIN)., PMID:39197587
Zanubrutinib is effective in non-germinal-center B-cell-like diffuse large B-cell lymphoma with mutated CD79B, high TCL1A expression, or over- expressed MYC/BCL-2., PMID:38775302
[Durable remission of T-cell prolymphocytic leukemia with CLEC16A::IL2 after allogeneic hematopoietic stem cell transplantation]., PMID:38311387
T-Cell Prolymphocytic Leukemia: Diagnosis, Pathogenesis, and Treatment., PMID:37569479
Subclinical rejection-free diagnostic after kidney transplantation using blood gene expression., PMID:36990211
BAFFR activates PI3K/AKT signaling in human naive but not in switched memory B cells through direct interactions with B cell antigen receptors., PMID:35767961
Deregulation and epigenetic modification of BCL2-family genes cause resistance to venetoclax in hematologic malignancies., PMID:35704690
[Analysis of the phenotypic heterogeneity of CD123-positive cells in Kikuchi-Fujimoto disease using a sequential immunoperoxidase labeling and erasing method]., PMID:34278759
Exploiting B-cell Receptor Stereotypy to Design Tailored Immunotherapy in Chronic Lymphocytic Leukemia., PMID:33051305
SLAMF6 as a Regulator of Exhausted CD8+ T Cells in Cancer., PMID:31315913
Pathogen-specific B-cell receptors drive chronic lymphocytic leukemia by light-chain-dependent cross-reaction with autoantigens., PMID:28899929
Whole-genome sequencing of chronic lymphocytic leukaemia reveals distinct differences in the mutational landscape between IgHVmut and IgHVunmut subgroups., PMID:28584254
TCL-1-positive hematogones in a patient with T-cell prolymphocytic leukemia after therapy., PMID:28232160
High-level ROR1 associates with accelerated disease progression in chronic lymphocytic leukemia., PMID:27815263
Primary testicular diffuse large B-cell lymphoma displays distinct clinical and biological features for treatment failure in rituximab era: a report from the International PTL Consortium., PMID:26308769
NANOG signaling promotes metastatic capability of immunoedited tumor cells., PMID:25899063
Primary mediastinal seminomas: a comprehensive immunohistochemical study with a focus on novel markers., PMID:25576290
Two types of BCR interactions are positively selected during leukemia development in the Eμ-TCL1 transgenic mouse model of CLL., PMID:25564405
Sequential chemoimmunotherapy of fludarabine, mitoxantrone, and cyclophosphamide induction followed by alemtuzumab consolidation is effective in T-cell prolymphocytic leukemia., PMID:23512246
Genome-wide detection of genes targeted by non-Ig somatic hypermutation in lymphoma., PMID:22808135
Chronic lymphocytic leukemia and regulatory B cells share IL-10 competence and immunosuppressive function., PMID:22713648
LPL is the strongest prognostic factor in a comparative analysis of RNA-based markers in early chronic lymphocytic leukemia., PMID:21508119
Aberrant microRNA expression in Chinese patients with chronic lymphocytic leukemia., PMID:21130495
AID-induced genotoxic stress promotes B cell differentiation in the germinal center via ATM and LKB1 signaling., PMID:20864035
Pluripotent reprogramming of fibroblasts by lentiviral mediated insertion of SOX2, C-MYC, and TCL-1A., PMID:20504151
[Immunohistochemical study using T-cell lymphoma antibody 1 and CD44 in diagnosis of Burkitt's lymphoma]., PMID:20079013
IGHV3-21 gene usage is associated with high TCL1 expression in chronic lymphocytic leukemia., PMID:19889012
High TCL1 levels are a marker of B-cell receptor pathway responsiveness and adverse outcome in chronic lymphocytic leukemia., PMID:19770358
Epstein-Barr virus infection leads to partial phenotypic reversion of terminally differentiated malignant B cells., PMID:19481340
T cell leukemia/lymphoma 1 and galectin-1 regulate survival/cell death pathways in human naive and IgM+ memory B cells through altering balances in Bcl-2 family proteins., PMID:19155496
Expression of TCL-1 as a potential prognostic factor for treatment outcome in B-cell chronic lymphocytic leukemia., PMID:17659340
EBNA2 interferes with the germinal center phenotype by downregulating BCL6 and TCL1 in non-Hodgkin's lymphoma cells., PMID:17151114
TCL1 shows a regulated expression pattern in chronic lymphocytic leukemia that correlates with molecular subtypes and proliferative state., PMID:16341048
Fluorescent-labeled DNA probes applied to novel biological aspects of B-cell chronic lymphocytic leukemia., PMID:15661260
T-cell prolymphocytic leukemia: update and focus on alemtuzumab (Campath-1H)., PMID:12623420
Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression., PMID:12011454
TCL1 oncogene expression in B cell subsets from lymphoid hyperplasia and distinct classes of B cell lymphoma., PMID:11304575
Regulation of TCL1 expression in B- and T-cell lymphomas and reactive lymphoid tissues., PMID:10786666
Purification and characterization of recombinant forms of murine Tcl1 proteins., PMID:10733880
Characterization and localization of the TCL-1 oncogene product., PMID:7987816
For research use only. Not for human or drug use.
