Catalog No.
PMC27101
Species reactivity
Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Mouse PSAP (Asn438-Tyr519).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Prosaposin, Sulfated glycoprotein 1, SGP-1, Saposin-A, Saposin-B-Val, Saposin-B, Saposin-C, Saposin-D, Psap, Sgp1
Purification
Purified by antigen affinity column.
Accession
Q61207
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Prosaposin hyperglycosylation: a novel tumor immune escape mechanism and implications for cancer immunotherapy., PMID:38982080
Prosaposin is a novel coenzyme Q10-binding protein., PMID:38510690
Diagnostic Role and Prognostic Impact of PSAP Immunohistochemistry: A Tissue Microarray Study on 31,358 Cancer Tissues., PMID:37892063
Tracking of Prosaposin, a Saposin Precursor, in Rat Testis., PMID:37728096
Single-cell multiomics revealed the dynamics of antigen presentation, immune response and T cell activation in the COVID-19 positive and recovered individuals., PMID:36532041
The expression of prosaposin and its receptors, GRP37 and GPR37L1, are increased in the developing dorsal root ganglion., PMID:34379697
Prosaposin in the rat oviductal epithelial cells., PMID:33242172
The L-domains in M and G proteins of infectious hematopoietic necrosis virus (IHNV) affect viral budding and pathogenicity., PMID:31610290
Development of parallel reaction monitoring assays for cerebrospinal fluid proteins associated with Alzheimer's disease., PMID:30858094
Skewed Invariant Natural Killer T (iNKT) Cells, Impaired iNKT:B Cell Help and Decreased SAP Expression in Blood Lymphocytes from Patients with Common Variable Immunodeficiency., PMID:29083052
Performance of different prostate specific antibodies in the cytological diagnosis of metastatic prostate adenocarcinoma., PMID:28888085
Production of monoclonal antibodies against the ORF3 protein of rat hepatitis E virus (HEV) and demonstration of the incorporation of the ORF3 protein into enveloped rat HEV particles., PMID:27638774
Prosaposin overexpression following kainic acid-induced neurotoxicity., PMID:25461957
Mesotrypsin and caspase-14 participate in prosaposin processing: potential relevance to epidermal permeability barrier formation., PMID:24872419
Temporal changes in prosaposin expression in the rat dentate gyrus after birth., PMID:24871372
Distribution of prosaposin in rat lymphatic tissues., PMID:23420452
Prosaposin, a regulator of estrogen receptor alpha, promotes breast cancer growth., PMID:22738294
Severe vestibular dysfunction and altered vestibular innervation in mice lacking prosaposin., PMID:22326583
The human female prostate-immunohistochemical study with prostate-specific antigen, prostate-specific alkaline phosphatase, and androgen receptor and 3-D remodeling., PMID:21810187
Amelioration of lupus nephritis by serum amyloid P component gene therapy with distinct mechanisms varied from different stage of the disease., PMID:21799927
Chronological changes in prosaposin in the developing rat brain., PMID:21684311
NKX3.1 as a marker of prostatic origin in metastatic tumors., PMID:20588175
Utility of racemase and other immunomarkers in the detection of adenocarcinoma in prostatic tissue damaged by high intensity focused ultrasound therapy., PMID:20025473
Regional expression of prosaposin in the wild-type and saposin D-deficient mouse brain detected by an anti-mouse prosaposin-specific antibody., PMID:19907127
Atypical ductal adenocarcinoma of the prostate with endometrioid immunohistological features., PMID:19601472
Expression of prostatic acid phosphatase (PSAP) in transurethral resection specimens of the prostate is predictive of histopathologic tumor stage in subsequent radical prostatectomies., PMID:19301031
Both the N-terminal fragment and the protein-protein interaction domain (PDZ domain) are required for the pro-apoptotic activity of presenilin-associated protein PSAP., PMID:18291114
Molecular characterization of feline immunodeficiency virus budding., PMID:18094166
Distribution of prosaposin in the rat nervous system., PMID:17763872
SGP-1 increases dendritic and synaptic development dependent on synaptic activity., PMID:17050025
Prosaposin upregulates AR and PSA expression and activity in prostate cancer cells (LNCaP)., PMID:17044040
Immunohistochemistry in diagnostic surgical pathology of the prostate., PMID:16512601
Saposin C: neuronal effect and CNS delivery by liposomes., PMID:16179529
Amplification and overexpression of prosaposin in prostate cancer., PMID:16080200
A novel Fasciola hepatica saposinlike recombinant protein with immunoprophylactic potential., PMID:15357089
Technical variations in prostatic immunohistochemistry: need for standardisation and stringent quality assurance in PSA and PSAP immunostaining., PMID:15220358
The flotillins are integral membrane proteins in lipid rafts that contain TCR-associated signaling components: implications for T-cell activation., PMID:12921760
Candidate gene approach: potentional association of caspase-1, inhibitor of apoptosis protein-1, and prosaposin gene polymorphisms with response to Salmonella enteritidis challenge or vaccination in young chicks., PMID:12887180
Molecular cloning of a member of the Fasciola hepatica saposin-like protein family., PMID:12880256
Transcriptional regulation of the cytosolic chaperonin theta subunit gene, Cctq, by Ets domain transcription factors Elk-1, Sap-1a, and Net in the absence of serum response factor., PMID:12788937
Regulation of sulfated glycoprotein-1 and cathepsin D expression in adult rat epididymis., PMID:12721218
Prosaposin ablation inactivates the MAPK and Akt signaling pathways and interferes with the development of the prostate gland., PMID:12647005
Procathepsin D interacts with prosaposin in cancer cells but its internalization is not mediated by LDL receptor-related protein., PMID:12083803
Candidate genes for resistance to Salmonella enteritidis colonization in chickens as detected in a novel genetic cross., PMID:12072268
Morphological and immunohistochemical characteristics of the heterogeneous prostate-like glands (paraurethral gland) seen in female Brown-Norway rats., PMID:11421491
Prosaposin is immunolocalized to muscle and prosaptides promote myoblast fusion and attenuate loss of muscle mass after nerve injury., PMID:11360264
Biogenesis of lysosomes in marshall cells and in cells of the male reproductive system., PMID:11335947
Immunophenotype of high-grade prostatic adenocarcinoma and urothelial carcinoma., PMID:11106075
Pepstatin A-sensitive aspartic proteases in lysosome are involved in degradation of the invariant chain and antigen-processing in antigen presenting cells of mice infected with Leishmania major., PMID:11027533
Immunohistochemical localization of prostate-specific antigen in ductal epithelium of male breast. Potential diagnostic pitfall in patients with gynecomastia., PMID:10937064
For research use only. Not for human or drug use.
